Correlation of cardiointervalometric and somatosensory evoked potential parameters in male and female patients with epilepsy
Year: 2017, volume 13 Issue: №1 Pages: 149-154
Heading: Neurology Article type: Original article
Authors: Lesik О.О., Zhadnov V.A.
Organization: Ryazan State Medical University n.a. I.L.Pavlov
Heading: Neurology Article type: Original article
Authors: Lesik О.О., Zhadnov V.A.
Organization: Ryazan State Medical University n.a. I.L.Pavlov
Summary:
Somatosensory evoked potentials and cardiointervalometry can be used as additional methods of examination of patients with epilepsy. Aim: determination of relationships between functional state of the brain and stress on regulatory systems, so as to assess the adaptive potential of male and female patients with epilepsy. Materials and methods. 46 male patients (group 1) and 34 female patients (group 2) diagnosed with epilepsy participated in the study. Analyzed parameters included maximum amplitude, total area of somatosensory evoked potentials and cardio-intervalometric parameters. Results. In patients with epilepsy, there is an increase in EAP indicators that suggestive of increased neu-ronal synchronization. However, with hyperventilation physiological probe, male patients demonstrated inhibition while female patients demonstrated stimulating effect of the brain. This tendency persisted in both groups of patients after hyperventilation. Cardiointervalometric findings in female patients were consistent with vagotony, indicative of normal activity of regulatory systems and the autonomous regulation of heart rhythm. Male patients with epilepsy require significant energy in order to adapt to the load, resulting to stress of regulatory systems. Conclusion. Additional methods of examination identify features of the functional state of the brain and stress on regulatory systems in male and female patients with epilepsy. Signs of disadaptation and unfavorable course ofthe disease allow timely diagnosis and improve the quality of life ofthe patient.
Bibliography:
1. Karlov VA. Epilepsy in children and adult females and males. M.: Meditsina Publishers, 2010; 720 p.
2. Zenkov LR. Clinical epileptology (with elements of neurophysiology). M.: LLC "Medical information Agency", 2002; 416 p.
3. Zenkov LR, Ronkin MA. Functional diagnosis of nervous diseases: guide for physicians. M.: Medpress-inform, 2011; 488 p.
4. Baevsky RM, Ivanov GG. Heart rate variability: theoretical aspects and clinical applications. Ultrasound functional diagnostics 2001; (3): 108-127
5. Algra A, Gates PC, Fox A. J, et al. Side of brain infarction and long-term risk of sudden death in patients with symptomatic carotid disease. Stroke 2003; 34 (12): 2871-2875
6. Carney RM, Blumenthal JA, Stein PK, et al. Depression, heart rate variability, and acute myocardial infarction. Circulation 2001; 104 (17): 2024-2028
7. Anokhin PK. Cybernetics of functional systems: selected works. M: Medicine, 1998; p. 397
8. Sudakov KV. System mechanisms of behavior. M.: Medicine, 1990; 240 p.
9. Zhadnov VA, Lapkin MM, Starikov AS. Physiological basis syndrome education in neurology at the example of epilepsy. Rossijskij medico-biologicheskij vestnik im. akademika I.P. Pavlova 2001; (3-4): 104-113
10. Kogan ВМ, DrozdovAZ, Dmitrieva ТВ. Mechanisms of development of somatic and psychiatric stress disorders (sexual and gender). Systemic psychology 2010. 1 (1): 52-60
11. Meller AM. Macmullen Stress in society and disorder, stress-related, in the aspect of gender differences. Social and clinical psychiatry 2004; (4): 5-11
12. Lightfoot JT. Sex Hormones Regulation of Rodent Physical Activity: A review. Int J Biol Sci 2008; 4 (3): 126-132
13. Wang J, Korczykowski M, Rao H, et al. Gender difference in neural response to psychological stress. Soc Cogn Affect Neurosci 2007; 2 (3): 227-239.
| Attachment | Size |
|---|---|
| 2017_01-1_149-154.pdf | 244.02 KB |
Русский
English