Saratov JOURNAL of Medical and Scientific Research

Ulcerative colitis: criteria and methods of prognosis of exacerbation

Year: 2014, volume 10 Issue: №3 Pages: 404-407
Heading: Internal Diseases Article type: Original article
Authors: Kashkina E.l., Fedosova M.A.
Organization: Saratov State Medical University
Summary:

Objective: research is devoted to the development of criteria and methods for prognosis of the next recurrence of exacerbation of ulcerative colitis (UC) after the patient discharged from hospital. Material and Methods: During a period of a year 38 patients with UC were supervised. The criteria used in the prognosis of recurrence included results of the evaluation of quality of life (SF-36 questionnaire), the analysis of the autonomic nervous system (coefficient Hildebrant and Kerdo index) and the level of stressful load procedure Holmes-Rage. Results. It has been established that the risk factors for recurrence include low quality of life on the scale of RP, SF and MH SF-36, the coefficient Hildebrant >5.6 units, Kerdo index 314 points. Conclusion: The obtained data have been processed by multivariate mathematical statistics and the obtained analytical expression allows to prognose the time of recurrence of ulcerative colitis.

Bibliography:
1. Kozlova HY. Psychosomatic features and quality of life of patients with peccurent non specific ulcerative colitis with differential pharmacological treatment of disease: PhD abstract. St. Petersburg, 2003; 19 p.; 2. Monstad I, Hovde О, Solberg 1С, Mourn В. Clinical course and prognosis in ulcerative colitis: results from population-based and observational studies. Ann Gastroenterol 2014; 27 (2): 95-104; 3. Graff LA, Walker JR, Clara I, Lix L, et al. Stress coping, distress, and health perceptions in inflammatory bowel disease and community controls. Am.J. Gastroenterol 2009; 104 (12): 2959-2969; 4. Adler G. Crohn's disease and non-specific ulcerative colitis. Moscow, 2001; 527 p. Russian (Адлер Г. Болезнь Крона и язвенный колит. М., 2001; 527 с.; 5. Maunder RG, Nolan RP, Hunter JJ, et al. Relationship between social support and autonomic function during a stress protocol in ulcerative colitis patients in remission. Inflamm Bowel Dis2012; 18 (4): 737-742; 6. Golisheva SV, Grigoreva GA. Quality of life as criteria effective methods of treatment of patients with ulcerative colitis and Crohn's disease. Doctor 2005; (7): 15-17; 7. Fedorova VL. Psichological mechanism of internal state of disease and relationship with stress situations of patients with inflamatine disease of intestine: PhD diss. (Psycological scienses). St. Petersburg, 2009; 190 p.; 8. Pica R, Cassieri С, Pronio AM et al. Quality of life in ulcerative colitis patients treated medically versus patients undergoing surgery. Eur Rev Med Pharmacol Sci 2014; 18 (5): 693-698.

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