Saratov JOURNAL of Medical and Scientific Research

Pregnancy associated plasma protein-A in acute coronary pathology.

Year: 2014, volume 10 Issue: №1 Pages: 92-95
Heading: Сardiology Article type: Original article
Authors: Sapozhnikov A.N., Razin V.A., Chernysheva E.M., Gimaev R.Kh., Kajumova G.Kh., Mazurova O.V., Akhmetshina D.I.
Organization: Ulyanovsk State University

The aim: to study pregnancy associated plasma protein A as a potential marker of myocardial necrosis with acute coronary syndrome. Material and methods. The rates of PPPP-A and insulin-like growth factor 1 were determined in 24 patients with acute myocardial infarction, in 18 patients with unstable angina and in the control group as well. Results. The rates of PPPP-A and ILGF-1 are accurately higher in the groups with acute coronary pathology in comparison to the patients with no ischemia. Conclusions. PPPP-A proves to be a marker of ischemia and/ or injury and could be used as a diagnostic predictor of an unstable atherosclerotic plaque in acute coronary development.

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