Saratov JOURNAL of Medical and Scientific Research

Procalcitonin as a diagnostic test for thermal injury

Year: 2014, volume 10 Issue: №1 Pages: 61-64
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Morrison V.V., Bozhedomov A.J.
Organization: Saratov State Medical University

Purpose: to determine the diagnostic value of procalcitonin in blood serum with probable development of multiple-organ-failure syndrome in thermal injury. Material and Methods. Procalcitonin test has been performed on the 1st, 3d, 7th, 15th and 30th days after the thermal injury. The expression of systemic inflammatory response syndrome (SIRS), leukocytic intoxication index (Lll) calculated according to Ya.Ya. Kalf-Kalif, levels of C-reactive protein, MCP-1, IL-6, VEGF, endothelin, and a number of circulating endothelial cells have been determined. Results. The increased level of procalcitonin (>0,5 ng/ml) in thermal injury has been observed in 42,7% of recovered patients and in 71,3% of dead patients. Conclusion. It has been found out that procalcitonin test in thermal injury may be used as an early marker for patients liable to develop polyorgan insufficiency syndrome.

Keywords: burns, procalcitonin, SIRS

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