Saratov JOURNAL of Medical and Scientific Research

Microelement content of bone tissue in transosseous osteosynthesis by II-izarov technique in high-altitude destinations (experimental research

Year: 2014, volume 10 Issue: №1 Pages: 119-123
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Erokhin A.N., Isakov B.D., Nakoskin A.N.
Organization: Bishkek State Medical Academy, Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics»

Aim: To study the redistribution of microelements in bone tissue in osteosynthesis in high-altitude destinations. Material and Methods. The study was performed on 72 mongrel dogs of both sexes aged 1-3 years, weighing 10—15 kg. 32 dogs have been experienced the extended leg in lowlands destinations, another group of 32 animals have been experienced elongation produced in high-altitude destinations. The control group consisted of 8 healthy dogs of low mountain areas. The standard technique of surgery has been used in the research. Microelement composition has been studied by atomic absorption spectrophotometer AAS-1 N (Germany) in the long bones and the distraction regenerate. Shapiro —Wilk test was applied to analyze the normality. The data evaluation has been done by Student's t-test for unpaired samples. Results. Calcium and microelement imbalance has been obtained during transosseous osteosynthesis in high-altitude destinations, which causes functional changes in the musculoskeletal system, with similar clinical picture of Kashin — Beck. In the conditions of high-altitude destinations elongation of bones causes changes in microelements in the distraction regenerate. Conclusion. During distraction osteosynthesis in high-altitude destinations phase changes of microelements have been formed in the bone regenerate, which prognoses physiologically the formation of a false joint.

1. Nagornaya NV, Bordyukova EV, Dubovaya AV, et al. The biological role of macro- and micronutrients in the body of the child, diagnosis, correction and prevention diselementozov: guidelines. Donetsk, 2010; 39 p.; 2. Skal'nyy AV, Rudakov IA. Bioelements in medicine. Moscow: Izdatel'skiy dom «ONIKS 21 vek» // Mir, 2004; 272 p.; 3. Gromova ОА, Kudrin AV. Neurochemistry of macro- and micronutrients: New approaches to pharmacotherapy. M.: Alev-V, 2001; 300 p.; 4. Spasov АА. Magnesium is in medical practice. Volgograd: Otrok, 2000; 272 p.; 5. Novikov Ml, Nakoskin AN. Dynamics of accumulation of trace elements in the tibia of dogs. Izvestiya Chelyabinskogo nauchnogo tsentra 2006; (3): 148-151; 6. Nakoskin АН, Novikov Ml. Content of macro- and micronutrients in ontogeny and in conditions of reparative bone regeneration in dogs. Travmatologiya i ortopediya Rossii 2008; (1): 38-43; 7. Leung KS, Cheung WH, Yeung HY. Effect of weightbearing on bone formation during distraction osteogenesis. Clin Orthop 2004;419:251-257; 8. Stogov MV, Kononovich NA, Nakoskin AN. Features osteoreparative processes in healing experimental fractures with varying degrees of bone marrow traumatization. Geniy ortopedii 2008; (2): 5-8; 9. Norms feed costs for laboratory animals in health care (Table 1 and 26). Appendix to Order of the USSR Ministry of the number 1179 Oct. 10, 1983; 10. Yerokhin AN, Isakov BD, Jumabekov SA. Peculiarities of homeostatic system in highland conditions using llizarov distraction transosseous osteosynthesis method. Saratov Journal of Medical Scientific Research 2012; 8 (2): 308-312; 11. Obukhov Al, Plekhanova Ю. Atomic absorption analysis in soil and biological research. Moscow: Izd-vo MGU, 1991; 184 p.; 12. Gromova ОА. Diagnosis and treatment of magnesium deficiency: teaching aid. Moscow, 2002; 13. Dedukh NV, Bengus LM, Basti A. Magnesium and bone. Osteoporoz i Osteopatii 2003; (1): 18-22; 14. Tikhonov VA. Kashin — Beck disease. Irkutsk: Vostochno-sibirskoe izdatel'stvo, 1976; 192 p.

2014_01_119-123.pdf388.02 KB

No votes yet