Epidemiological monitoring the of Parkinson's disease morbidity
Year: 2013, volume 9 Issue: №4 Pages: 873-877
Heading: Neurology Article type: Original article
Authors: Krivonos О.V., Smolentseva I.G., Amosova N.A.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Heading: Neurology Article type: Original article
Authors: Krivonos О.V., Smolentseva I.G., Amosova N.A.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:
Aim: the analysis of epidemiological monitoring of Parkinson's disease. Material and Methods. We conducted the full-design population study in the six closed administrative-territorial unit (Seversk, Zarechniy, Ozersk, Lesnoy, Sarov and Zheleznogorsk) with an adult's population about 450000 in the period from 2009 to 2012. For collecting information was developed the register of PD. Results. 588 patients with PD were revealed and enrolled, including 302 patients, who were revealed in the first. Primary morbidity was 11.0 per 100000 population in 2009, and in 2010 and 2011 it was 25.7 and 22.7 per 100000 population respectively. By the beginning of 2012 was so-called "dredging" of patients from population (revealing of all patients, who were not revealed earlier) and was 8.5 per 100000. Total morbidity for 4 years of observation increased: so in 2009 it was 33.1 per 100000, in 2010-92.5 per 100000, in 2011-114,2 per 100000, and in 2013-118,7 per 100000, the same like international data. The Evolution of sex and age structure according to the Register's data showed: 1) peak of morbidity at age 70-74 years, with the decay over 85 years; 2) morbidity was higher in men aged 70-74 years and older. Conclusion. Implementation of the Register of PD's patients annually allowed to monitoring of the morbidity and statistically significant show the basic epidemiological evidence and undertake federal and sampling comparative studies, it is necessary for evaluation of the changes of Parkinson's disease status, which can't be done on the basis of the state statistical dates.
Bibliography:
1. Lonneke M.L. de Lau, Monique M.B. Breteler. Epidemiology of Parkinson's disease // Lancet Neurol. 2006, Jun. № 5 (6). P. 525-535;
2. The influence of age and gender on motor and non-motor features of early Parkinson's disease: Initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort / K. Szewczyk-Krolikowski, P. Tomlinson, K. Nithi [et al.] // Par-kinsonism Relat Disord. 2013, Oct. 12. pii: S1353-8020 (13) 00356-8. doi: 10.1016;
3. Shtok V. N., Levin O.S., Ivanova-Smolenskaja I.A. Jek-strapiramidnye rasstrojstva. M., 2002;
4. Epidemiology and etiology of Parkinson's disease: a review of the evidence / K. Wirdefeldt, H.O. Adami, P. Cole [et al.] // Eur.J. Epidemiol. 2011, Jun. №26. Suppl. 1: S1-58. doi: 10.1007;
5. Freire O, Koifman S. Pesticide exposure and Parkinson's disease: epidemiological evidence of association // Neurotoxicol-ogy. 2012, Oct. №33(5). P. 947-971. doi: 10.1016;
6. Levin O. S, Fedorova N. V. Bolezn' Parkinsona. 3-е izd. M.: MEDpress-inform, 2012. 352 s.;
7. Jepidemiologija parkinsonizma/E.A. Katunina, G.N.Avak-jan, Ju.N. Bezdol'nyj [i dr.] //Zhurnal nevrologii i psihiatrii. 2009. №11. S. 76-80;
8. Parkinson's disease in China: prevalence in Beijing, Xian, and Shanghai /Z.X. Zhang, G.C. Roman, Z. Hong [et al.] // Lancet. 2005. № 365. P. 595-597;
9. Driver J.A., Logroscino G., Gaziano J.M., Kurth T. Incidence and remaining lifetime risk of Parkinson disease in advanced age // Neurology. 2009. № 72. P. 432-438;
10. Levin O.S., Dokadina L.V. Jepidemiologija parkin-sonizma i bolezni Parkinsona // Nevrol. zhurn. 2005. № 5. P. 41-48;
11. Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity / S. K. Van Den Eeden, С. M. Tanner, A.L. Bernstein [et al.] // Am. J. Epidemiol. 2003. №157. P. 1015-1022;
12. Diem-Zangerl A., Seppi K., Oberaigner W., Poewe W. Mortality in Parkinson's disease, a 20-year follow-up study // Mov. Disord. 2010. № 25. P. 661-662;
13. Pohabov D.V., Abramov V. G., Nesterova Ju.V. Jepidemiologija parkinsonizma (po materialam registra v Krasnojar-skom krae): ruk-vo dlja vrachej po materialam 1-go Nacional'no-go kongressa. M., 2008. S. 20-27;
14. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030 / E. R. Dorsey R. Constantinescu, J.P. Thompson [et al.] // Neurology. 2007. № 68. P. 384-386;
15. Katunina E.A., Bezdol'nyj Ju.N. Jepidemiologicheskie issledovanija parkinsonizma: metod. rekomendacii RGMU. M., 2010. S. 3-43.
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