Saratov JOURNAL of Medical and Scientific Research

№4, 2010, volume 6

Academic Aleksandr Nikolaevich Bakulev (Dedicated to the 120-th Anniversary of His Birth)

Year: 2010, volume 6 Issue: №4 Pages: 870-874
Heading: Scientific schools Article type:
Authors: Popkov V.M., Zavyalov A.I.
Organization: Saratov State Medical University

The article presents biographic information about academician A.N. Bakulev, his scientific and practical contribution to the development of cardiovascular and thoracic surgery, neurosurgery and creation of scientific surgery school in the USSR

Keywords: surgery, biography, academician A.N. Bakulev

The 20th anniversary of orthopaedic stomatology of Saratov State Medical University n.a. V.I. Razumovsky

Year: 2010, volume 6 Issue: №4 Pages: 867-869
Heading: Scientific schools Article type:
Authors: Kirichuk V.F., Googe LA., Rosalieva Yu.Yu.
Organization: Saratov State Medical University

Development of stomatology as speciality in the second half of the XXth century determined the necessity of organization of stomatological faculty in Saratov State Medical Institute. For the period of 20 years department of orthopaedic stomatology has formed the teaching staff of prospective young professionals graduated from Saratov State Medical University

Keywords: stomatological faculty, research work, practical work, orthopaedic stomatology, department

Insulinotherapy as a medico-social phenomenon and quality of life of patients with type 1 diabetes mellitus

Year: 2010, volume 6 Issue: №4 Pages: 863-866
Heading: Endocrinology Article type: Review
Authors: Kargina L.V., Dorogoykin D.L., Rodionova T.I., Utts I.A.
Organization: Saratov State Medical University

The article examines the factors influencing availability of insulinotherapy, modern insulin types, methods of insulin administration, and insulin pump as one of its number. The authors explicate some challenges connected with availability of insulin therapy for patients with type 1 diabetes mellitus belonging to various social groups

Keywords: type 1 diabetes mellitus, insulinotherapy, insulin pumps, availability

The interaction of public-school teachers with student users of psychoactive substances

Year: 2010, volume 6 Issue: №4 Pages: 857-862
Heading: Pedagogics and Education Article type: Original article
Authors: De Castro Rossi L.C., Dalben I., Mangini Bocchi S.C.
Organization: Brazil, Botucatu

The increasing and early use of psychoactive substances by children and adolescents represents a challenge to public-health practice. To understand teachers' interactions with student users of drugs and develop a representative theoretical model of such experience this study was conducted. Qualitative study conducted in Sro Paulo, Brazil, with 32 teachers from public schools by means of focal groups and based on the Grounded Theory as its methodological framework. Progressively comprehensive categories converged to three phenomena: Identifying student's users; Feeling powerless in face the challenges of drugs use; Silencing to preserve oneself from a threatening scenario. These phenomena constructed the core category of the experience: Silencing to preserve oneself from a threatening scenario in face of the fragility of rescuing student's users of drugs. The clash between inducing and protective factors in the concrete situations of drugs use was revealed, thus pointing out that the lack of State and social support associated with the user's relation with drug trafficking and violence leads teachers to silence as they feel unprotected in face of a situation surrounded by stigma and prejudice. Coping strategies should include the educators, relatives, health care professionals and government institutions, thus providing ways to prevent and treat use, orientate and reconstruct lives in a process of active participation for all students

Keywords: schoolchildren's health, qualitative research, grounded theory, disorders related to substance use, adolescent

New approach to surgery in obliterating atherosclerosis of lower limb arteries

Year: 2010, volume 6 Issue: №4 Pages: 850-856
Heading: Surgery Article type: Original article
Authors: Kazantsev A.M., Korymasov E.A.
Organization: Samara State Medical University

Complex examination of 296 patients with obliterating atherosclerosis of lower extremities was carried out. Prog-nostically significant clinical, hemodynamic, hemostatic, immunological characteristics, markers of endothelial dysfunction and changes in lipid profile in patients were studied. Pathogenetic system of disease prognosis was worked out as a result of multifactor analysis where the index of course of disease was accounted. When the index was lower than + 13, obliterating atherosclerosis was not considered as progressive. Progressive atherosclerosis was determined with the index over the point +13

Keywords: prognosis, low limb atherosclerosis, index of disease course

Application of automated morphometric method of estimation of expression of immunohistochemical markers in diagnostics of prostate and bladder cancer

Year: 2010, volume 6 Issue: №4 Pages: 845-849
Heading: Urology Article type: Original article
Authors: Popkov V.M., Ponukalin A.N., Maslyakova G.N., Tsmokalyuk E.N., Bucharskaya A.B., Shirokov A.A., Burov A.M.
Organization: Saratov State Medical University, Institute of Biochemistry and Physiology of Plants and Microorganisms of Russian Academy of Sciences

The diagnostic significance of molecular markers was evaluated by immunohistochemical research of surgical and biopsy material of 106 patients with diseases of bladder and 57 patients with diseases of prostate. They received treatment at Scientific Research Institute of Fundamental and Clinical Uronephrology with monoclonal antibodies: Ki-67, PCNA, p63 (markers of proliferative activity), p53 (suppressor of tumor growth), Bcl-2, Bax (markers of apoptosis), EGFR (receptor of epidermal growth factors), PSA, PSMA, AMACR (prostate-specific antigens) and cytokeratin profile. The morphometric research was conducted on the basis of automated analysis system of digital images Ariol SL50 (Genetix)

Keywords: prostate cancer, molecular markers, immunohistochemistry, diagnostic significance, bladder cancer

Dynamics of concentrations of immunoglobulins M, G, A classes in the blood serum in patients with bronchopulmonary complications in the acute and early periods of the cerebrospinal trauma

Year: 2010, volume 6 Issue: №4 Pages: 841-844
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Konjuchenko Е.А., Ulyanov V.Ju., Puchinyan D.M., Karjakina E.V.
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics

The article presents research data on immunoglobulin concentration of M, G, A classes in blood serum in 15 patients with bronchopulmonary complications during acute and early periods of trauma in cervical spine. Control group consisted of 15 healthy donors - volunteers. Concentration dynamics of levels of lg M, lg G, lg A in the blood serum on the 1st-4th, 7th, 14th, 21st and 30th days was studied. Hardphase method of immune analysis based on the «sandwich» principle was used. It was stated that hypogammoglobulinemia lasted during the whole acute period of spinal cord injury

Keywords: immunoglobulins of M, G, A classes, cerebrospinal trauma, broncho-pulmonary complications

Different approaches to total knee replacement: a comparative research

Year: 2010, volume 6 Issue: №4 Pages: 834-841
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Zelenyak К.В., Serebryakov A.B.
Organization: Moscow Center for Treatment and Rehabilitation, Moscow

Purpose: to compare traditional and miniinvasive approaches to total knee replacement.
145 patients were divided in four groups. In 1 group (50 pts) we used medial parapatellar approach, 2 group (30 pts) - lateral parapatellar approach, 3 group (34 pts) - midvastus approach, 4 group (31 pts) - Q-S approach. All replacements were done by one experienced surgeon. Intraoperative blood loss, duration of surgery, results of KSS and quality of positioning of implants were measured. Mininvasive approaches to knee replacement showed decreased blood loss, improved functional results and positioning was as much perfect, as with traditional approach. Mininvasive knee replacement is very effective, but it should be performed by experienced surgeon

Keywords: miniinvasive replacement, knee, approach

Treatment technique of diaphyseal fractures of shin bones according to biomechanical influence on reparative osteogenesis phases

Year: 2010, volume 6 Issue: №4 Pages: 829-834
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Barabash А.Р., Rusanov A.G., Barabash Yu.A., Alfimov R.A.
Organization: Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics, Central Municipal Hospital of Pyatigorsk

The article deals with new treatment technique in fractures of shin bones. It combines ideal reduction of damaged bone with reposition device without transition of transosseous elements through muscular masses, adequate fixation of bone fragments and change of biomechanical efforts in apparatus according to reparative osteogenesis phases. It is performed due to application of external fixation apparatus

Keywords: transosseous osteosynthesis, reparative phases, fractures of shin bones

Clinical way method in treatment of out-patients with ischemic heart disease after cardiosurgery

Year: 2010, volume 6 Issue: №4 Pages: 824-828
Heading: Sociology of Medicine Article type: Original article
Authors: Vardosanidze S.L., Galstyan A.S.
Organization: Stavropol State Medical University

158 patients with ischemic heart disease (IHD) have been understudy during the period of 12 months in out-patient conditions. After completion of the primary examination all the patients of basic group (118 patients) received clinical way method of treatment. Patients of the comparison group (40 patients) after provided treatment were cared by their local therapeutists (cardiologists). The findings proved the fact that treatment of patients after cardiosurgery by clinical way method in out-patient conditions enabled to raise patient motivation to treatment, thereby assisting them to feel better, promoting normalization of arterial pressure data. The research results stated that clinical way method of treatment may be considered as rational and effective

Keywords: stenting, ischemic heart disease, coronary artery bypass grafting, clinical way