CROHN’S DISEASE DIAGNOSTICS IN ACUTE STAGE WITH THE USE OF HIGHLY EFFECTIVE LIQUID CHROMATOGRAPHY BLOOD SERUM
Year: 2008, volume 4 Issue: №2 Pages: 82-85
Heading: Internal Diseases Article type: Original article
Authors: N.N. Mironov, S.V. Nasonov, O.P. Alekseeva, S.V. Krishtopenko
Organization: Gastroenterological Centre of Volga Region Federal District of the Russian Federation, Nizhni Novgorod, Nizhni Novgorod Regional Clinical Hospital named after N.A.Semashko, «Medical Diagnostics» Ltd, Nizhni Novgorod
Heading: Internal Diseases Article type: Original article
Authors: N.N. Mironov, S.V. Nasonov, O.P. Alekseeva, S.V. Krishtopenko
Organization: Gastroenterological Centre of Volga Region Federal District of the Russian Federation, Nizhni Novgorod, Nizhni Novgorod Regional Clinical Hospital named after N.A.Semashko, «Medical Diagnostics» Ltd, Nizhni Novgorod
Summary:
15 patients with the endoscopically and morphologically verified diagnosis of the Crohn’s disease and 14 healthy humans at the age of 23- 24 years have been examined. The Crohn’s disease index activity was 235 - 310 units. The possibility highly effective liquid chromatography blood serum use for diagnosis of the disease has been studied. A blood serum dried extract has been investigated on the "Milichrome A 02" chromatograph (Novosibirsk, "Econova "joint-stock company). The chromatograms have been treated with the use of a multilevel cluster analysis with a pathologic three-measured state form, differing from a healthy human. A diagnostic sensitivity and accuracy of the method has achieved 100%.
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