Saratov JOURNAL of Medical and Scientific Research

Psoriasis as system pathology

Year: 2008, том 4 Issue: №1 Pages:
Heading: Reviews Article type: Original article
Authors: Bakulev A.L., Shagova Yu.V., Kozlova I.V.
Organization: Saratov State Medical University
Summary:

Psoriasis is one of the most widespread chronic dermatoses which 1 -5 % of the population of the planet suffers. They consider psoriasis as a systemic disease with not only lesions of skin, but also joints and visceral involvement, as «psoriasis disease». In the review there are discussed pathogenesis of psoriasis, submitted infectious-immunological, genetic, metabolic and neuroendocrine concepts. Changes of digestive, cardiovascular, nervous, hepatobiliary, urinary systems and suppoting-motive apparatus of patients with psoriasis are examined. Methods of treatment of psoriasis are presented. Immunosuppressive and anticytokine therapy is dscussed.

Psoriasis is one of the most widespread chronic dermatoses which 1 -5 % of the population of the planet suffers.
They consider psoriasis as a systemic disease with not only lesions of skin, but also joints and visceral involvement, as «psoriasis disease». In the review there are discussed pathogenesis of psoriasis, submitted infectious-immunological, genetic, metabolic and neuroendocrine concepts.
Changes of digestive, cardiovascular, nervous, hepatobiliary, urinary systems and suppoting-motive apparatus of patients with psoriasis are examined. Methods of treatment of psoriasis are presented. Immunosuppressive and anticytokine therapy is dscussed.

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