№1, 2008, volume 4

Changes of rheological blood properties of were studied in 91 women with physiological course of pregnancy. The control group was formed of 21 nonpregnant women. During physiological course of gestation the following dynamical changes of haemorheologic data were observed: phase changes of blood viscosity and plasma viscosity, increase of
serum blood viscosity. These changes have adaptive character and promote formation of optimal conditions for fetus growth and development.

In modern stomatology the problem ofatypicalforms ofinflammatoryperiodontaldiseases origination, namely of rapidly progressive periodontitis (RPP), has got special importance due to its widespread. The article presents one of the impotant parts of the pathogenesis- the disturbance of microcirculation processes caused by the decrease of blood clot resistencyofa vascularwall in pathogenesis ofmicrocirculatori disorders in patients with RPP. These disturbances are predetermined by endothelial dysfunction with the subsequent degradation of the clinical presentation of disease, the stomatologic status and quality of patients life.

The present research is focused on defining the role of protein С system in the process of blood coagulation and fibrinolysis in patients suffering from different forms ofperiodontitis.
The beginning of specific course of treatment in patients with chronic periodontitis there have been diagnosed disturbances in protein С system, the latter being the reason for blood coagulation disorders, such as: the decrease of protein С activity, the decrease of active factor Va resistance, the increase ofplasminogen reserve, the decrease of total antithrombin blood activity, antithrombin III activity including. The degree of changes in protein С system depends on the severity degree of chronic periodontitis: the more severe disease is the more severe disorders itcauses in protein С system. The most evident symptoms of depression of indices in protein С system were observed in patients with quick-progressive periodontitis. The decrease of protein С activity is caused by its consumption in the process of intravascular blood coagulation is characteristic periodontitis.

Individual and anatomical peculiarities of dimensions and shape of the orbitofadult peoples (n=102) were studied with different shape of the facial cranium. More expressed dimensions of the superior and lateral walls of the orbit in leptoprozopic and eurioprozopic shape of the cranium. Depth of the orbitdependon of shape of the facial cranium.

Investigated features of a body build of 309 young men and girls of the Penza region in the age of 16-21 years. B.A.Nikitjuk andA.I.Kozlov methodwas applied to definition of type of a body build. The Penza youth is characterized by prevalence among young men of faces brachymorphic normotrohpical type, with distribution of hypodermic Adeps mainly below a girdle and on a trunk. Among girls there are people mesomorphic body builds hypotrophical type, distribution of hypodermic Adeps mainly below a girdle and on extremities is more often. In both groups on the average there are no surpluses of mass of a body.

Morphometric measuring of ll-V finger’s phalanxes were held on 150 pasportized sets of right hands. Different variations of phalanxes in length, base height and head’s height, and also their main morphometric parameters were determined.

The parameters of a vascular bed (vascular volume in % andvasculardencityon 1 mm2 of tumor) were estimated on the operational-bioptic aspirate of the primary tumor of 83 patients with the ovary cancer (ОС). The immunohistochemical method with the use of mice monoclonal antibodies p53, clone DO-7, lgG2b(M7001 DakoCytomation) has been applied for the estimation of the level of p53 expression. Based on the estimated parameters we can conclude that there is no distinctive group of differences among the different clinical stages of the ОС. However, there is a weak positive correlation between the volume and density of vessels and the disease stages. At the same time, the quantity of the atypical epithelial cells of the primary tumor that express p53 is significantly increasing in each subsequent stage. The results of the research show the possible p53 inactivation in the tumor cells and the stimulatory role ofp53in the neoangiogenesis in the course of the tumor progression.

In this overview there is given the information about the diagnostic possibilities of ultrasound and magnetic-resonance tomography of cancer prostate both on early and developed stages of the pathological process.

Saratov State Medical University Research Institute for Fundamental and Clinical Urology Nephrology
Renal masses are widespread pathology with high mortality and morbidity rate. Early diagnostics is a possibility of nephron-spearing surgery. Ultrasonography is screening imaging modality for renal lesions, Doppler investigation provide possibility for vascularity of these masses evaluation. CT with and without contrast enhancement can be used as a marker of malignancy. Magnetic resonance imaging has been proposed for the evaluation of renal lesions, especially in cases in which ultrasonography (US) and/or CT results are not definitive.

Psoriasis is one of the most widespread chronic dermatoses which 1-5% of the population of the planet suffers. They consider psoriasis as a systemic disease with not only lesions of skin, but also joints and visceral involvement, as «psoriasis disease». In the review there are discussed pathogenesis of psoriasis, submitted infectious-immunological, genetic, metabolic and neuroendocrine concepts. Changes of digestive, cardiovascular, nervous, hepatobiliary, urinary systems and suppoting-motive apparatus of patients with psoriasis are examined. Methods of treatment of psoriasis are presented. Immunosuppressive and anticytokine therapy is discussed.