Saratov JOURNAL of Medical and Scientific Research

persistence

The microecological and immunological problems of persistention of Helicobacter pylori

Year: 2016, volume 12 Issue: №1 Pages: 19-26
Heading: Microbiology Article type: Review
Authors: Belova O.L., Schelekhova T.V., Belova I.M.
Organization: Saratov State Medical University
Summary:

The interrelation of persistence of Helicobacter pylori in stomach with innate and adaptive immunity of human has been discussed. The analysis of the mechanisms of immunological recognition of the antigens of this microorganism and response to them has been performed. It has been considered, that the development and course of gastritis and ulcer in human with Helicobacter pylori stipulate for inadequate reactions of immune system and common reactivity by the individual organism in presence of Helicobacter pylori in mucus of stomach.

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2016_01_019-026.pdf1.23 MB

Detection of Chlamydia trachomatis in blood samples as a diagnostic method for complicated and persistent forms of urogenital chlamydia infections

Summary:

Goal: the study of the effectiveness of the method for laboratory diagnostics of urogenital chlamydial infection in patients with chronic form of the disease. Material and methods. The presence of DNAof C. trachomatis was detected by PCR in either genital or extragenital (blood) sites in eighth patients (four men and four women). Results. It is established that in biological material taken from extragenital (blood) sites, C. trachomatis was detected in all patients examined (in 100% of cases), while in clinical samples obtained from genital sites, in seven patients only (87.5%). Conclusion. We found that specific chlamydial DNAcan be detected in extragenital (blood) site, despite the negative reaction in the clinical material from the genital tract of patients with genital chlamydial infection.

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2015_03-01_381-385.pdf321.91 KB

Rotavirus infection in children: clinical and laboratory features and catamnesis

Year: 2013, volume 9 Issue: №3 Pages: 504-508
Heading: Infectious Diseases Article type: Original article
Authors: Mikhailova E.V., Levin D.U., Danilov A.N., Koshkin A.P., Lavrentiev G.P.
Organization: Saratov State Medical University
Summary:

Purpose is to study the clinical, laboratory and instrumental characteristics of the course of rotavirus infection in children up to 3 years in the acute phase and during the convalescence period. Material and methods. A clinical, laboratory and instrumental examination of 320 children up to 3 years with moderate to severe rotavirus infection. Results. The presence of long-term persistence of rotavirus recovering from rotavirus infection. Identified functional disorders of the digestive system in the acute period and the period of convalescence in children up to 3 years with rotavirus infection. Conclusion. For a long period (up to 3 months), almost half of patients may experience intestinal dysfunction, possibly related to the long-term persistence of rotavirus.

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2013-03_504-508.pdf276.45 KB