Saratov JOURNAL of Medical and Scientific Research

stress

Influence of drinking behavior on the content of alpha-amylase of oral fluid in students with and without predictor of inflammation on the background of educational stress

Year: 2019, volume 15 Issue: №1 Pages: 9-13
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Baisheva GM, Melnik KN.
Organization: Togliatti Clinical Hospital №5, Samara State Medical University
Summary:

 The aim: to study the content of a-amylase in oral fluid in healthy young people (mean age 18 years), depending on the presence of a predictor of inflammatory diseases of the oral cavity in physiologically adjusted drinking behavior against the background of educational stress. Material and Methods. For three months, we studied three groups: the main group (30 people, consumed water 30-35 ml per 1 kg of body weight treated with the electromagnetic device), a placebo group (30 people used water 30-35 ml per 1 kg of body weight, but consumed water with a placebo device that does not have an electromagnetic base) and a control one (25 people who do not change their water drinking behavior). To identify the features of sAA oscillations, all groups were divided into subpopulations with predictors of inflammatory diseases of the oral cavity (IL-1(3>212 pg/ml) and without such status (IL-1(3<212 pg/ml). The level of a-amylase activity was determined by a colorimetric method on Cobas C111 automated equipment (Roche), the concentration of IL-1J3 was detected by ELISA on an Infinity F50 photometer (Tecan). Results. Secretory alpha-amylase activity by the end of the study decreased in the main group; in the placebo and control groups, baseline values were exceeded. In the subpopulations with predictors of inflammatory dental diseases (IL-1(3<212 pg/ml) of the main group, the sAA activity decreased by 2.5 times; in the subpopulations without predicates of inflammatory changes (IL-1(3 <212 pg/ml), a significant decrease in enzyme activity in the main group was observed and an increase in the control. The percentage of sympathotonics at the end of the experiment in the main group was lower than in the placebo and control groups. Conclusion. A relation was found between a decrease in the level of a-amylase activity in the oral fluid and corrected water drinking behavior in a subgroup of people without predictors of inflammatory diseases of the oral cavity, using water in an amount of at least 30-35 ml/kg body weight that was purified by an electromagnetic method.

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Psoriasis onset risk assessment in persons with hereditary predisposition with age, stress level and eating behavior taken into account

Year: 2018, volume 14 Issue: №4 Pages: 751-754
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A.
Organization: Saratov State Medical University
Summary:

Purpose: to analyze the significance of stress levels and psychology of eating behavior in people with hereditary predisposition for psoriasis for assessment of psoriasis manifestation risk in the next three years. Material and Methods. Two hundred eighty seven people aged 21-63 years with newly diagnosed psoriasis were investigated. All patients were surveyed using Holmes — Rahe Stress Inventory to assess their stress levels and Dutch Eating Behavior Questionnaire to determine the type of their eating behavior. Results. It has been established that external and emotional eating behavior in people with hereditary predisposition to psoriasis is an unfavorable prognostic factor for manifestation of dermatosis at an earlier age. Conclusion. In persons with hereditary burden index over 0.6 units psoriasis can manifest with stress level below 150 points, as determined by Holmes — Rahe questionnaire, while in persons with a hereditary burden index below 0.2 units disease manifestation is largely associated with a stress level over 300 points.

Antistress activation therapy for cardiovascular diseases

Year: 2016, volume 12 Issue: №4 Pages: 696-701
Heading: Cardiology Article type:
Authors: Miroshnik E.V., Yeliseyeva N.A.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The cohort pilot study had been done. Aim: to study the effectiveness of an antistress activation therapy on the functional state of human with the purpose of formation of adaptive reactions of activation and training high levels of reactivity among the two groups of patients with cardiovascular problems, ranks first among causes of death population: arterial hypertension (AH) and coronary heart disease (CHD). Material and methods. From the sub-sample of the Moscow population (396) were allocated to 2 groups of patients of 30 people in each (a control group and a group for anti-stress therapy for persons with hypertension and coronary artery disease that within 1 month took adaptogens (tincture of ginseng, Eleutherococcus, etc.) is minimized by a specially developed algorithm. For stress diagnosis international integrated questionnaire Perceived Stress (PSS); as well as Hospital Anxiety and Depression Scale (HADS) were used. Blood pressure, heart rate, body mass index, waist circumference were measured. In addition we used new methods "Antistress activation health improvement". Results. The average age in the intervention group was 59.4 years, and in the control group was 58.3 years, p>0.05. In compliance with results of the study has been marked that persons who were treated by methods "Antistress activation health improvement" sensed general and "internal" dumping, improving of duration and quality of sleeping. Irritability, level of stress, depression, and fatigability became rather less. Dynamics of emotions locked in psychometric scales showed distinct improvement of mood, decrease of fear, sorrow, anxiety, anger, emotional instability, increase of self-reliance, activity. Conclusion. The treatment of stress, anxiety, and depression must be complexes based on biological and psychological approaches.

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State of cardiovascular system during exercise in sportsmen

Year: 2013, volume 9 Issue: №1 Pages: 64-68
Heading: Internal Diseases Article type: Original article
Authors: Usanov D.A., Protopopov А.А., SkripalA.V.,AveryanovA.P., Kashchavtsev Е.О.
Organization: Saratov State Medical University, Saratov state university
Summary:

The purpose of the article is to study the state of cardiovascular system of sportsmen involved in rowing and canoeing, both before and after training. Material et methods: The research has been performed by means of the developed mobile devices that allow non-invasive screening assessment of the potential risk of collapse complications. Results: The article outlines the results of the survey carried out to determine the presence of vagotonic tone with deficient activity supply and abnormal pulse wave that may lead to circulatory collapse in exercise. Conclusion: The technique of pulse wave and vegetative regulation assessment before and after training enables to prevent the circulatory collapse development in stressful physical exertion in sportsmen.

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Influence of personality characteristics on spectrum of catecholamines and course of ischemic heart disease in elderly patients

Year: 2012, volume 8 Issue: №4 Pages: 942-946
Heading: Internal Diseases Article type: Original article
Authors: Prokhorenko I.О., Zarubina Е.G.
Organization: Samara Medical Institute «Reaviz»
Summary:

Purpose: the study of interrelation between characteristics of psychological profile of elderly patients, level of stress hormones in blood serum and character of IHD course. Materials and Methods. The level of catecholamines and cortisol in blood was investigated in two groups of elderly patients (379 patients) formed according to their psychological profile with the help of Cattell questionnaire. Multispiral coronarography was conducted in patients suffering IHD. Results. The established differences of stress level correlated with the characteristics of the course of IHD at all the
examined patients. In spite of various levels and reactions of adaptive hormones on stress situations the prevalence of IHD appeared to be the same in both groups although manifestation and clinical severity of coronary insufficiency varied in patients of different groups. The number of patients suffered myocardial infarction, among them with Q-wave, occurred to be higher in one of the groups despite the fact that changes in their coronary arteries were less expressed. Conclusion. The character of psychological profile causes different stress resistance of patients and leads to various levels of stress hormones in blood serum. Depression can become a marker of severe course of cardiovascular pathology. The character of psychological profile influences the course of IHD.

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Role of personal psychological profiles in somatic pathology development

Year: 2011, volume 7 Issue: №2 Pages: 415-418
Heading: Internal Diseases Article type: Original article
Authors: Prokhorenko I.O., Zarubina E.G.
Organization: Samara Medical Institute «Reaviz»
Summary:

The research goal is to examine the correlation between psychological profile of patients of senior age groups, levels of stress hormones — adrenaline and noradrenaline — in blood serum and their pathology character. A psychological profile of 247 patients aged from 55 to 82 years has been established with the help of Kettle test, Tsung self-assessment scale and Spilberger-Khanin scale. The rate of adrenaline and noradrenaline in blood serum in the period of exacerbation of somatic pathology and in the period of relative well-being has been estimated by means of immune-enzyme analysis method. The survey has identified three psychological profiles. The first and third groups are less resistant to stress factors psychological types. They are more likely to develop somatic pathology and depression (37,8 and 53,2% respectively), in comparison with patients of the second group (12,5%). The significant increase of catecholamines has been established among patients of the third type of psychological profile both in the period of exacerbation of somatic pathology and in the period of relative well-being. The article concludes that correlations between psychological personality characteristics, rate of catecholamines and structure of somatic pathology have been worked out

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Topicality of ischemic heart disease prophylaxis in specialists of medical-social expertise

Year: 2011, volume 7 Issue: №2 Pages: 387-389
Heading: Physiology and Pathophysiology Article type: Author's opinion
Authors: Krovyakova Е.А., Kirichuk V.F., Kodochigova A.I.
Organization: Saratov State Medical University
Summary:

Realization of professional duties for specialist of medical-social expertise is accompanied with high intellectual and emotional obligations. Daily extreme and psychogenic situations lead to psychological and occupational maladjustment of physicians, development of anxiety and depression among them, which can be exacerbated by the presence of alexithymia. Negative psycho-emotional factors increase the risk of coronary heart disease. In order to prevent this pathology development in specialists of medical-social expertise, identification of changes in their psycho-emotional sphere and personified correction of revealed disorders are necessary

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Clinical, psychophysiological and psychological aspects of risk factors of periodontal disease development in clinically healthy persons

Year: 2009, volume 5 Issue: №4 Pages: 516-520
Heading: Physiology and Pathophysiology Article type: Original article
Authors: O.V. Medvedeva, V.F. Kirichuk, A.I. Kodochigova, M.G. Kucherov, I.N. Nikulina
Organization: St. Petersburg State University, Saratov State Medical University, Penza Regional Children's Clinical Hospital n.a. N.F.Filatov
Summary:

The research goal is to determine risk factors of periodontal disease development, psychophysiological personal types and their interrelations in clinically healthy persons. 47 first-year cadets of St.-Petersburg Military School of radio electronics have been examined. This group of respondents has been chosen by presence of such social stressor as change of place of living (97,9% cadets have arrived in St.-Petersburg from other cities and republics of the Russian Federation) and strict disciplinary conditions. The research has revealed a low level of oral hygiene, cases of mild gingivitis in most respondents. The general mental state of group under study is characterized by raised level of personal anxiety and low indices of reactive anxiety. The examined group has demonstrated anxiety, tension, indecision and lowered stress stability. Clinically healthy persons are more liable to develop inflammatory and inflammatory-destructive periodontal diseases. It was possible to determine psychophysiological features correlated with physiological parameters of risk degree of periodontal diseases. It may have a great significance in defining of periodontal disease etiology and pathogenesis

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Influence Of Terahertz Range Electromagnetic Radiation At Molecular Spectrum Frequency Of 150+0,75 Ghz Nitric Oxide On Microcirculation Morphofunctional Disturbances In White Rats In Condition Of Acute And Prolonged Stress

Year: 2009, volume 5 Issue: №4 Pages: 511-516
Heading: Physiology and Pathophysiology Article type: Original article
Authors: I.O. Bugaeva, V.F. Kirichuk, A.N. Ivanov, M.O. Kurtukova
Organization: Saratov State Medical University
Summary:

The effect of electromagnetic radiation of terahertz range at frequency of emission and absorption molecular spectrum of 150+0,75GHz nitric oxide on morphofunctional changes of microcirculation and tissue structure in animals in condition of acute and prolonged immobilization stress has been studied. It has shown that the influence of electromagnetic waves at these frequencies causes activity decrease of hypothalamic-pituitary-adrenal and tireoyd axis of stress reaction. It has been determined that terahertz range waves at frequency of nitric oxide are liable to restore disturbances of intravascular, vascular and extravascular components of microcirculation and also have histoprotective effect

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Morphological Features Of Lymphoid Structures Of Rat Inguinal Lymph Nodes In State Of Emotional Stress With Preliminary Injection Of Oligopeptides

Year: 2009, volume 5 Issue: №4 Pages: 493-497
Heading: Macro- and Micromorphology Article type: Original article
Authors: А.А. Bakhmet
Organization: First Moscow State Medical University n.a. I.M. Sechenov
Summary:

The lymphoid structures of inguinal lymph nodes and cells of the peripheral blood of 104 Vistar male rats of both experimental and control groups have been investigated by means of modern hystological and immunohystochemical methods. It has been revealed that the delta-sleep inducing peptide (DSIP) and Semax (synthetic analogue of ACTH 4-10) preliminary injection causes emotional stress influence on the increase of proliferative and destructive mac-rophage processes in the actively functional zones of inguinal lymph nodes. The relative quantity of small lymphocytes in the germinal centers of lymphoid nodules of inguinal lymph nodes has decreased in 1,3 per hour after the emotional stress in comparison with the indices of control groups. After the injection of DSIP the quantity of small lymphocytes resistant to stress in animals has decreased insignificantly, as for rats predisposed to stress it has increased in 1,2 in comparison with the data of control groups. It has been found out that the DSIP and Semax injection decreases stressinduced condition of lymphoid cells in peripheral blood as well as in lymphoid structures of inguinal lymph nodes

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