Saratov JOURNAL of Medical and Scientific Research

bone defect

Treatment of bone defects of tibia edge during external anchorage of fragments

Year: 2017, volume 13 Issue: №3 Pages: 727-731
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Grazhdanov К.А., Barabash А.Р., Barabash Yu.A., Rusanov A.G., Kauts O.A.
Organization:
Summary:

The aim: to identify the efficiency of the improved technology of treatment of tibia marginal defects with the use of granular composite osteoplastic materials during external fixation of fragments. Material and Methods. The observation group was made up of 12 patients with the consequences of lower extremity traumas who had undergone osteosyn-thesis of fractures by an external fixation device with defect alloplasty We used clinical and ray-tracing testing methods and also standardized system of assessment of outcomes of bone fractures and their consequences to control the processes of restoration of bone structure integrity. Results. According to the standardized system of assessment of outcomes in 12-18 months in the course of the rehabilitation measures degree of restoration of anatomic functional indices was 92±5%. Bone density made up 91,3±0,54 HU (p<0,05) before surgery according to the Hounsfield scale, increase in the given parameter was observed in a month and a half after surgery up to 153,1 ±0,97 HU and in 3 months up to 162,7±0,78 HU. Conclusion. Application of granular composite osteoplastic materials for plastic surgery of tibia marginal defects during external fixation of fragments allow us to carry out anatomic reconstruction of the bone reducing surgery injury rate based on the absence of necessity of taking autogenous tissues from the other zones.

AttachmentSize
2017_03-2_727-731.pdf1.03 MB

Evaluation of the effectiveness of a resorbable membrane «Bio-Gidein» in combination with chitosan for the treatment of bone defects

Year: 2014, volume 10 Issue: №2 Pages: 239-245
Heading: Macro- and Micromorphology Article type: Original article
Authors: Kalmin O.V., Nikishin D.V., Volodina Yu.M.
Organization: Penza State University
Summary:

Objective: to evaluate the efficiency of a resorbable membrane «Bio-Gide» in combination with chitosan for guided bone regeneration during the degradation under the experimental conditions. Material and Methods. The histological methods provide the study of tissue samples from 6 adult rabbits from artificial mandible through 14, 28 and 42 days after surgery. In group 1 the treatment was carried out without the use of additional materials, by a blood clot. In group 2 closing of the damaged area was produced by xenopericardial plate «Bio-Gide» in combination with chitosan. Results. It has been established that the conduct of bone wound under a blood clot causes inflammatory response on the 14th day after the operation, to the 28th day inflammation disappears and it practically does not appear on the 42nd day. Closure of the bone defect using xenopericardial plate «Bio-Gide» with chitosan causes lesser inflammatory response. In the long-term period after the surgery inflammatory changes in the implantation can not be detected. Conclusion. Xenopericardial plate «Bio-Gide» in combination with chitosan has a positive impact on the recovery process of the bone defect. Neoplasm of bone occurs, the stage of development of cartilage is shortened. At the end of the experiment period xenopericardial plate is not detected indicating the high rate of its biodegradation.

AttachmentSize
2014_02_239-245.pdf2 MB

Combined osteoplasty of metaepiphysial defects in total knee arthroplasty with osteoplastic biomaterial

Year: 2012, volume 8 Issue: №4 Pages: 971-974
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Girkalo М.V., Gavrilov М.А., Kozlov V.V.
Organization:
Summary:

The research goal is to study the results of osteoplastic biomaterials application to reach the improvement of primary and long-term secondary stability of fixation. Materials and methods: 62 patients with bone defect of metaepiphy-sis of type 2 according to AORI have been included into the research. Total knee arthroplasty with osteoplasty of the defect has been carried out in all the patients. In the basic group (n=32) combined osteoplasty has been used, and in comparison group (n=30) cement osteoplasty has been applied. In cases with total arthroplasty in the basic group modifying standard resections, structural autograft of laminar form has been received simultaneously. After preparing the floor of the defect its plasty has been carried out: in the basic group the defect has been filled with osteoconductive biomaterial, and in the comparison group — with polymethylmethacrylate to restore the anatomical configuration of condyles. Besides, before cement fixation of the prosthesis in the basic group the received autograft has been put on the restored implant plateau. Results: Assessing the results during the period from 2 to 4 years objective criteria have included the data of X-ray imaging, biomechanical research and WOMAC test. In the postoperative period significant differences have not been revealed. In the follow-up period in the group with application of the combined osteoplasty joint remodulation of autograft and osteoplastic biomaterial with regenerative restoration of bone tissue of the implant plateau has been observed. Conclusion: The described technique may reduce the relative risk of revision arthroplasty.

AttachmentSize
201204-971-974.pdf509.14 KB