Saratov JOURNAL of Medical and Scientific Research

Moissev A.A.

Saratov State Medical University n.a. V.I. Razumovsky Assistant of the Department of Dermatology and Vene-reology and Cosmetology

Clinical case of a very rare form of keratodermia in a child

Year: 2018, volume 14 Issue: №4 Pages: 763-765
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenko V.M., Moiseev A.A., Ulanova A.M., Dobdina A.Yu.
Organization: Saratov State Medical University
Summary:

 Cases of keratoderma are the most common among genodermatoses and take the second place after a group of ichthyosis. The frequency of occurrence of keratodermia in the world, including Russia, is from 1:300 to 1:15000. There is a very rare form of diffuse keratoderma: Olmsted Syndrome, which in 2009 is described in 10 sources of scientific literature. The defeat not only affects the palms and soles, and skin around the orifices, forms a flexion deformity and con-tracture fingers, until spontaneous amputation. Some observations noted the presence of follicular keratosis of the extremities, leukokeratosis on the face and language, pererastayut joints, alopecia, absence of premolars. We present a clinical case of a patient with this pathology.

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Neurofibromatosis in the practice of dermatology

Year: 2018, volume 14 Issue: №4 Pages: 760-763
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenko V.M., Moiseev A.A., Sherstobitova K.Yu., Ishmukhametova R.A.
Organization: Saratov State Medical University
Summary:

Neurofibromatosis belongs to the group of systemic hereditary diseases from the group of phakomatosis, characterized by developmental defects of ectodermal and mesodermal structures, mainly of the skin, nervous and bone systems, with an increased risk of developing malignant tumors. There are 7 types of the disease include a wide range of clinical manifestations even within the same family: a progressive course, the involvement of almost all organs and systems in the process, a high risk of complications, including many serious and fatal (cardiovascular) pulmonary insufficiency due to severe skeletal abnormalities, malignant degeneration by neurofibromas, etc.). An analysis of 5 clinical cases with neurofibromatosis is presented.

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Resonance radio wave diagnosis of localized sclerodermia: pilot study

Year: 2017, volume 13 Issue: №3 Pages: 585-590
Heading: Dermatovenerology Article type: Original article
Authors: Moiseev A.A., Utz SR.
Organization: Saratov State Medical University
Summary:

The purpose of the research was to study the diagnostic possibilities of the use of the active radiometry method for localized scleroderma (LS), both for monitoring the results of therapy, and for a comprehensive assessment of the functional state of body tissues in the study area, as well as the possibility of determining new foci of the disease. Material and Methods. In a pilot study, patients were presented with different forms of lesions and their different localization, as well as with different disease activity. The method of resonance wave diagnostics is implemented in the diagnostic complex "Aquafon". Results. The primary registration of wave activity in different types of foci may differ. The activity of the foci and the possibility of the appearance of new foci can be said not so much by the data of the initial measurements as by the integral data on their difference before and after the illumination procedure, which requires further study. Conclusion. It is necessary to improve the measurement technique, avoid places where the sensor is not well attached to the skin or minimize this effect. The research also aimed to conduct studies with simultaneous use of other methods.

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Modern methods of a localized scleroderma diagnostics

Year: 2016, volume 12 Issue: №3 Pages: 481-484
Heading: Dermatovenerology Article type: Review
Authors: Moiseyev А.А., Utz S.R.
Organization: Saratov State Medical University
Summary:

Localized scleroderma (LS) is a disease that is characterized by the appearance of inflammatory, sclerotic and/or atrophic changes in the affected areas of the skin and underlying tissues. In ICD-10, the disease is considered under category L94 "Other localized connective tissue changes". This paper presents the classification of the disease developed for federal guideline 2015, for management of patients with localized scleroderma. Also, a brief description of the various methods of diagnosis of the disease, including laboratory tests, instrumental methods and disease severity scale are presented.
Keywords: scleroderma, diagnostics, dermatology.

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Fatal cerebrospi-nal meningitis due to Treponema pallidum infection

Year: 2012, volume 8 Issue: №2 Pages: 494-499
Heading: Neurology Article type:
Authors: Maslyakova G.N., Kolokolov O.V., Lukina, E.V., Kolokolova A.M., Abramova T.P., Moiseev A.A.
Organization: Saratov State Medical University
Summary:

We report the case of young patient, whose cause of death was generalized syphilitic cerebrospinal meningitis. The results of autopsy and histological examination are presented. The possibility of using magnetic resonance imaging to verify the form of neurosyphilis is discussed.

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