Saratov JOURNAL of Medical and Scientific Research

diabetic retinopathy

Retrospective analysis of retinal laser coagulation outcomes in diabetic retinopathy

Year: 2020, volume 16 Issue: №4 Pages: 895-899
Heading: Ophtalmology Article type: Original article
Authors: Goydin А.Р., Fabrikantov O.L., Shutova S.V., Lev I.V., Manaenkova G.E.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution, Tambov State University n. a. G.R. Derzhavin
Summary:

Purpose: to analyze clinical and functional results of panretinal laser coagulation (PRLC) in patients with Diabetic retinopathy (DR) and diabetes mellitus type II. Material and Methods. We performed a retrospective 4-year analysis of the results of pattern PRLC in diabetic retinopathy in 1326 patients (1646 eyes) with diabetes mellitus type II. All patients were divided into groups: group I with PRLC only, group II —with additional PRLC, group III with vitreoretinal surgery, distributing by the groups with best-corrected visual acuity (BCVA). Results. The distribution of the observed cases in three groups depended on the initial visual acuity, approximately uniform distribution by groups with BCVA with a decrease above 0.8 was noted in group I, in group II on the contrary — the greater number of cases in the group above 0.8, and in group III — in groups under 0.4. The analysis of BCVA within the follow-up showed that in group I visual acuity stayed the same within two years, in group II — within 12 months, in group III — up to 6 months with a subsequent significant decrease. By difference in losses of BCVA in group I and II losses did not exceed 1 line in 60%, and in group III only in 44%. Conclusion. PRLC in diabetic retinopathy in patients with diabetes mellitus type II allowed preserving high visual acuity with a loss of not more than 0.2 line within 4-year follow-up in 72% of cases, and in cases of timely treatment by a single PRLC — in 79%. PRLC allowed stabilizing DR within 4 years in 69% of cases, preserving high visual acuity in 72%. In DR progression 22% required additional PRLC and 9% —vitreoretinal surgery that was associated with the late treatment.

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Estimation of diagnostic value of optical coherence tomography angiography parameters in patients with diabetic retinopathy

Year: 2020, volume 16 Issue: №1 Pages: 210-215
Heading: Ophtalmology Article type: Original article
Authors: Goydin А.Р., Fabrikantov O.L., Pronichkina M.M., Misyurev D.M.
Organization: Tambov State University n.a. G.R. Derzhavin, S. Fedorov Eye Microsurgery Federal State Institution
Summary:

The purpose of the study is to estimate diagnostic value of optical coherence tomography angiography (OCT-angiography) parameters in patients with diabetic retinopathy. Material and Methods. The investigation included 102 patients with diabetes mellitustype II and different stages of diabetic retinopathy and 48 clinically healthy people. Apart from routine ophthalmological examination all patients underwent optical coherence tomography of the macular area. To estimate diagnostic value of OCT-angiography, we performed ROC-analysis of the most informative parameters. Results. The most significant differences in OCT-angiography data between patients with different stages diabetic retinopathy (groups I and II) and healthy people (control group) were noted for general vascular density in all sectors (Whole image) and parafoveal zone (Parafovea) of the superficial vascular plexus. The ROC-analysis showed high sensitivity and specificity of the same zones for control group and group I, as well as for groups I and II. Conclusion. The capillary network density for Parafovea in patients with diabetes mellitus is less than 52% and for Whole image it is less than 48.5%, which indicates the presence of non-proliferative and pre-proliferative retinopathy, while the reduction of Parafovea parameters lower than 43.6% and Whole image lower than 47.5% indicates proliferative diabetic retinopathy.

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Medical and social aspects of diabetes and diabetic retinopathy.

Year: 2017, volume 13 Issue: №3 Pages: 453-457
Heading: Health Service Organization Article type: Original article
Authors: Velichko Р.В., Osmanov Е.М., Manyakov R.R.
Organization: "Eye Microsurgery" n.a. academician S. N. Fedorov, Volgograd branch, Tambov State University n. a. G.R. Derzhavin
Summary:

The aim of the article: to study the medical and social aspects of diabetes mellitus and diabetic retinopathy at the regional level. Material and Methods. The prevalence, structure and dynamics of diabetes and diabetic retinopathy (DR) were analyzed among the population of the Tambov region for a seven-year period from 2010 to 2016 based on statistical compendiums on the main indicators of health facilities and the health of the population of the Tambov region (2010-2016) Russian statistical yearbooks (2010-2016), data from the regional State register of patients with diabetes. Results. In 2016 in the Tambov region, the prevalence of DR in type 1 diabetes is 53.2%, with type 2 diabetes 31.2%, significantly higher than all-Russian indicators, which were registered at 27.2% in patients with type 1 diabetes and 13.0% of patients with type 2 diabetes. Conclusion. The results of the comparative analysis of the level and structure of diabetes and DR indicate a negative trend among the population of the Tambov region, which dictates the need to develop effective and inexpensive methods for preventing the development and progression of DRs and making management decisions based on them.

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Erythropoietin in patients with type 1 diabetes (review)

Year: 2012, volume 8 Issue: №1 Pages: 159-163
Heading: Endocrinology Article type: Review
Authors: Khantakova Е.А., Khamnueva L.Yu.
Organization: Irkutsk State Medical University
Summary:

The article analyzes the literature on the issue of regulation of erythropoietin in patients with type 1 diabetes. The connection between the secretion of erythropoietin disturbance with the development and progression of diabetes complications has been observed. Various pleiotropic effects of erythropoietin have been considered

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