Saratov JOURNAL of Medical and Scientific Research

Magdeeva N.A.

Saratov State Medical University n.a. V. I. Razumovsky, Department of Hospital Therapy of Medical Faculty, Assistant, Candidate of Medical Science

Amiodarone-induced skin damage: clinical observation

Year: 2019, volume 15 Issue: №3 Pages: 741-744
Heading: Cardiology Article type: Case report
Authors: Kosheleva N.A., Magdeeva N.A., Frontaseva V.V., Alekseeva I.L., Fedoritova M.O.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

Nowadays one of the most often used antiarrhytmic drugs is amiodarone. Amiodarone is the most effective drug for sinoatrial rate preservation at fibrillation of auricles, the only agent with the proved ability to reduce mortality in patients with cardial pathology and ventricular arrhythmias. On the other hand, amiodarone is the "reserve" drug due to its side effects. In this observation the patient was on amiodarone in the course of 5 years due to paroxysms of auricles fibrillation. After 4 years of drug therapy grayish-blue local areas appeared on open body parts (i. e. face, hands). After drug with drawal the intensity of skin staining decreased. In this clinical case skin hyperpigmentation was amiodarone side effect and did not require any special treatment.

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Rituximab treatment efficacy in a patient with systemic lupus erythematosus with severe thrombocytopenia

Year: 2018, volume 14 Issue: №3 Pages: 417-419
Heading: rheumatology Article type: Case report
Authors: Alexandrova O.L., Nikitina N.M., Magdeeva N.A., Shmelkova M.Yu., Grigoryeva S.N.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

The article presents a clinical case of systemic lupus erythematosus with severe thrombocytopenia in a 55 year old patient. The standard therapy of usage of high doses of glucocorticoids, cyclophosphamide and intravenous im-munoglobulin was not effective. Application of Rituximab improved the course of disease, decreased the severity of thrombocytopenia, led to disappearance of leucopenia and anemia.

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A clinical case of fast progression of amyloidosis of kidneys in rheumatoid arthritis

Year: 2017, volume 13 Issue: №4 Pages: 821-823
Heading: Internal Diseases Article type: Case report
Authors: Romanova I.A., Magdeeva N.A., Nikitina N.M.
Organization: Saratov State Medical University
Summary:

The article presents clinical case of unfavorable outcome of amyloidosis of kidneys in a patient with rheumatoid arthritis. The absence of basic treatment and persistent activity of disease leads to fast progression of nephrotic stage of secondary amyloidosis in a young woman.

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Systemic Lupus Erythromatosis or Hiv Infection «Mask»?

Year: 2009, volume 5 Issue: №3 Pages: 444-446
Heading: Practice physician Article type: Short message
Authors: Е.Н. Скрябина, Н.А. Магдеева, И.Ф. Нам
Organization: Saratov State Medical University, Saratov Regional Clinical Hospital
Summary:

The difficulties while conducting the differential diagnosis between systemic lupus erythromatosis (SLE) and HIV infection due to their clinical resemblance are reflected in this article

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PECULIARITIES OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH GOUT AND ITS CHANGES DURING THE TREATMENT

Year: 2008, volume 4 Issue: №3 Pages: 59-62
Heading: Internal Diseases Article type: Original article
Authors: A.P. Rebrov, N.A. Magdeeva
Organization: Saratov State Medical University
Summary:

The purpose of the present work was to study questions connected with peculiarities of endothelial dysfunction in patients with gout Anticoagulant and fibrinolytic activities and activityofVillebrand factor were investigated. We have revealled endothelial dysfunction, which expressiveness decreased after 3-months treatmentin patients with gout

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AMLODIPINI IN THE MANAGEMENT OF HYPERTENSIVE PATIENTS WITH GOUT

Year: 2008, volume 4 Issue: №1 Pages: 72-75
Heading: Internal Diseases Article type: Original article
Authors: A.P. Rebrov, N.A. Magdeeva
Organization: Saratov State Medical University
Summary:

The aim of the present work was a detailed study of questions connected with the peculiarities ofcircadian blood pressure profile, efficiency of amlodipine in patients with goutand arterial hypertension. We used 24-hour blood pressure monitoring before and after 3-months treatment. Patients with gout showed the disturbances of circadian blood pressure profile (Non-dipper). Prolonged calcium antagonists are the best drugs for the hypertensive patients with gout.

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