Saratov JOURNAL of Medical and Scientific Research

Shulaeva N.M.

Saratov Burn Centre, Head of Anesthesiology and Resuscitation Ward

Cytoprotective effect of cytoflavinum at treatment of thermal injury of various severity level

Year: 2012, volume 8 Issue: №1 Pages: 038-042
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Bozhedomov A.J., Morrison V.V., Shulaeva N.M., Nikitina V.V., Ivanenko I.L.
Organization: Saratov State Medical University, Saratov City Clinical Hospital №7
Summary:

The purpose of research was studying of cytoprotective effect of cytoflavinum at a thermal trauma of different severity level. Materials and methods. 169 patients with thermal burns with a favorable outcome and gravity of a thermal trauma from 30 to 170 points on Franc were under research. 28 patients took standard dosage of cytoflavinum while complex therapy. Results. Patients with thermal trauma more than 60 points on Franc took Cytoflavinumuse and demonstrated decrease in intensity of system inflammatory response syndrome (SIRS), reduction of band neutrophils portion, lowering of erythrocyte number, smaller activation ofthrombocytopoiesis, dicrease of concentration of vascular endothelial growth factor. Positive effect was not revealed in group of patients with thermal trauma less than 60 points who received cytoflavinum. Conclusion. Use of cytoflavinum was the most effective at thermal trauma gravity more than 60 points on Franc

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