Saratov JOURNAL of Medical and Scientific Research

spectroscopy

Comparative evaluation of clarifying agents to improve the quality of the far long-wave ultraviolet therapy chronic dermatosis

Year: 2016, volume 12 Issue: №3 Pages: 453-458
Heading: Dermatovenerology Article type: Original article
Authors: Artemina Е.М., Utz S.R., Yuvchenko S.A., Zimnyakov D.A., Alonova M.V.
Organization: Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University
Summary:

Objective; to choose the optical clearing agent with the best illuminating ability in the long-wave UV spectrum used in phototherapy. Material and methods. Ex vivo skin samples were used as objects of study. Measurement of the total transmission spectra of the skin sections was carried out on a multi-channel spectrometer Ocean Optics QE 65000 (Ocean Optics, USA) using 4 optical clearing agents (40% glucose solution, glycerol, propylene glycol, oleic acid).
Results. Having conducted a comparative analysis of ex vivo data collected from spectroscopy of these optical clearing agents at a wavelength of 370 nm, it was found that the maximum optical clearing was achieved using propylene glycol at 44 minutes, which was 11.56%. Conclusion. The use of optical clearing agents is possible not only to improve the visualization of the skin structure, but also to explore the dynamics of light transmission in long-wave UV A-1 therapy of patients.

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General methods of identification of narcotic substances in cadaveric urine and biochemical indices in blood at positive identification of drug substances

Year: 2011, volume 7 Issue: №3 Pages: 642-646
Heading: Narcology Article type: Original article
Authors: Bychkov E.N., Serkova S.A., Arsentieva L.A., Frantsuzova T.S., Bluvshtein G.A., Borodulin V.B.
Organization: Saratov State Medical University, Saratov Bureau of Forensic Medical Examination
Summary:

The goal of the present paper was to find effective biochemical markers of chronic narcotization. Materials and methods. The results of biochemical research of biological liquids in human organism and chromatographic methods of drug substances identification in cadaveric urine were analyzed. Research of 197 samples of different biologic liquids of 10 persons was carried out. Control was fulfilled on the basis of 135 samples of biological liquids took of 12 persons. Methods of identification of drug substances are presented, chromatographic and spectral characteristics of drug substances are described. Interrelations of biochemical indices at positive study of drug substances identification were conducted. The increased urea metabolic concentration in cadaveric blood of drug addicts was revealed in comparison with control specimens. Results. (Numeral results are given in Table 3). Correct correlation of biochemical markers was not established. Conclusion. The present results suppose continued study of informative reliable biochemical markers of chronic drug intoxication

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