Saratov JOURNAL of Medical and Scientific Research

Marchenko V.M.

Saratov State Medical University n.a. VI. Razumovsky, Clinic of Skin and Venereal Diseases, Head of the Hospital ER

Clinical case of a very rare form of keratodermia in a child

Year: 2018, volume 14 Issue: №4 Pages: 763-765
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenko V.M., Moiseev A.A., Ulanova A.M., Dobdina A.Yu.
Organization: Saratov State Medical University
Summary:

 Cases of keratoderma are the most common among genodermatoses and take the second place after a group of ichthyosis. The frequency of occurrence of keratodermia in the world, including Russia, is from 1:300 to 1:15000. There is a very rare form of diffuse keratoderma: Olmsted Syndrome, which in 2009 is described in 10 sources of scientific literature. The defeat not only affects the palms and soles, and skin around the orifices, forms a flexion deformity and con-tracture fingers, until spontaneous amputation. Some observations noted the presence of follicular keratosis of the extremities, leukokeratosis on the face and language, pererastayut joints, alopecia, absence of premolars. We present a clinical case of a patient with this pathology.

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Neurofibromatosis in the practice of dermatology

Year: 2018, volume 14 Issue: №4 Pages: 760-763
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenko V.M., Moiseev A.A., Sherstobitova K.Yu., Ishmukhametova R.A.
Organization: Saratov State Medical University
Summary:

Neurofibromatosis belongs to the group of systemic hereditary diseases from the group of phakomatosis, characterized by developmental defects of ectodermal and mesodermal structures, mainly of the skin, nervous and bone systems, with an increased risk of developing malignant tumors. There are 7 types of the disease include a wide range of clinical manifestations even within the same family: a progressive course, the involvement of almost all organs and systems in the process, a high risk of complications, including many serious and fatal (cardiovascular) pulmonary insufficiency due to severe skeletal abnormalities, malignant degeneration by neurofibromas, etc.). An analysis of 5 clinical cases with neurofibromatosis is presented.

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Epidemiological features of scabies and STI in the Saratov area from 1991 till 2010

Year: 2012, volume 8 Issue: №2 Pages: 657-659
Heading: Skin Diseases Article type: Original article
Authors: Utz S.R., Zavyalov A.I., Marchenko V.M., Reshetnikova E.M., Yepifanova A.U.
Organization: Saratov State Medical University
Summary:

The study presents the comparative analysis of scabies and STI incidence in different groups of population in Saratov region from 1991 till 2010. Principal causes and factors supporting epidemic process of infectious diseases in this region on an extent of 2 decades are revealed. It is established that if the basic group patients with scabies were children, teenagers and people at the age from 20 to 29 years, so, in the group with STI there were patients aged from 18 to 29 years. Besides, it was proved that over the last years early and late latent forms of syphilis and neurosyphilis prevail among patients in age group from 40 to 60 years. It leads to disability, and sometimes invalidism quite often.

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Clinical and epidemiological signs of scabies and modern methods of diagnostics and treatment (review)

Year: 2011, volume 7 Issue: №3 Pages: 636-641
Heading: Skin Diseases Article type: Review
Authors: Utz S.R., Zavialov A. I., Marchenko V.M.
Organization: Saratov State Medical University
Summary:

The research work provides summary on diagnostics and treatment of scabies. Russian and foreign medical literature has been analyzed. Modern situation of epidemiology, different clinical forms of scabies and some cases of non-effective treatment have been considered

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