Saratov JOURNAL of Medical and Scientific Research

Voskresenskaya O.N.

Saratov State Medical University, Head of Department of Neurology, Professor, Doctor of Medical Science

Parkinson's disease in Russia: prevalence and incidence

Year: 2016, volume 12 Issue: №3 Pages: 379-384
Heading: Neurology Article type: Review
Authors: Razdorskaya V.V., Voskresenskaya O.N., Yudina G.K.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The results of the regional studies on the frequency of Parkinson's disease (PD) and the incidence of it in Russia have been generalized, the main factors that determine the quality of the estimates of this disease epidemiological indicators have been identifyd. The article summarizes data from 19 original studies on the epidemiology of parkinsonism and Parkinson's disease in Russia published between 2005-2015. Due to the statistical heterogeneity of the primary results computational analytics was not applied to the data; however, data consolidation allowed to perform a trend analysis of epidemiological indicators. The methodological basis of the majority of studies was medical aid appealabil-ity; two of the studies used door-to-door surveys. One of the studies returned questionably low epidemiological indicators obtained from the medical records, and the rest showed the standardized prevalence of 30.0-139.9/100,000 and incidence of 7.63-21.8/100,000 per year. Contribution of Parkinson's disease to the nosological structure of parkinsonism was >61.3%. Estimate of the number of patients with PD in Russia is approximately 210,000 people. Conclusions are made regarding the prevalence of PD in Russia according to the cross-cutting research on the level of indicators in the Western countries. The prevalence of PD by appealability is 2-3 times less than the prevalence in continuous research, both national and foreign. The incidence of PD, demonstrated in half of the studies, is stable from region to region and is comparable with the universally recognized values.

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The diagnostic reliability of outpatient neurological care to patients with Parkinson’s disease

Year: 2012, volume 8 Issue: №2 Pages: 513-517
Heading: Neurology Article type: Original article
Authors: Razdorskaya V.V., Voskresenskaya O.N., Yudina G.K.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Goal: discussion of the revealing aspects of Parkinson’s disease (PD) by ambulatory neurologists. Techniques: a longitudinal epidemiological survey on applications to a specialized clinic. Results. 603 patients with Parkinsonism suspicions were examined for a four-year period. The syndromal diagnosis of Parkinsonism/extra pyramidal syndrome was correctly recognized by ambulatory neurologists in ca. ¾ of the whole contingent of patients. Hypodiagnostics of PD was the most frequent mistake (71 of 146 corrected diagnoses). Hyperdiagnostics of PD followed by frequency (57 of 146 corrected diagnoses). Every ffth patient applied for consultation caused diffculties in the ambulatory chain. Conclusion. The diagnostic mistakes, no provisional diagnosis for every tenth PD patient cause justifed anxiety in the patients regarding the quality of guaranteed medical aid and force them to apply for specialized consulting reception individually.

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Clinical aspects and characteristics of the course of Parkinson’s disease with chronic cerebral ischemia

Year: 2012, volume 8 Issue: №2 Pages: 491-494
Heading: Neurology Article type: Original article
Authors: Makarov N.S., Spiridonova S.V., Voskresenskaya O.N.
Organization: Clinical hospital n.a. S. R. Mirotvortsev SSMU, First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The article is devoted characteristics current of Parkinson’s disease with chronic cerebral ischemia. Objective: to study the clinical presentation and features of PD against cerebral ischemia. Methods. A total of 44 patients with a diagnosis of “Parkinson’s disease”, 20 of which were determined by accurate clinical and instrumental signs of chronic cerebral ischemia. Comparative characteristics of the neurological status, cognitive functions, some laboratory and instrumental data in the two groups of patients: Parkinson’s disease with a background of chronic ischemia of the brain and without it. Results. Statistically signifcant differences between groups are observed on the following variables: duration of illness, severity of depression, the concentration of glucose in the blood. Formed groups of signifcant difference in the severity of atherosclerosis of cerebral vessels. Conclusion. The data of the acceleration of the progression of Parkinson’s disease with chronic cerebral ischemia, as well as the more frequent occurrence of depression in this patient group.

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Road one hundred years long: history of neurology development in Saratov

Year: 2012, volume 8 Issue: №2 Pages: 357-364
Heading: Neurology Article type: Review
Authors: Popkov V.M., Protopopov A.A., Alenkina E.V., Sholomov 1.1., Voskresenskaya O.N., Kolokolov О.V.
Organization: Saratov State Medical University, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

The article presents information about the history of neurology in Saratov.

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Diagnostics and treatment of vascular parkinsonism

Year: 2010, volume 6 Issue: №1 Pages: 120-123
Heading: Neurology Article type: Review
Authors: V.V. Yudina, O.N. Voskresenskaya, G.K. Yudina
Organization: Saratov State Medical University
Summary:

The article presents clinical syndromic classification of parkinsonism in relation to etiological factors. It also studies epidemiologic and historical aspects of vascular parkinsonism. the research work demonstrates clinical patterns, clinical pathologico-morphological criteria and clinical neurovisualizing correlations of postinsult and noninsult variants of vascular parkinsonism. the principles of basic and symptomatic treatment of vascular parkinsonism are considered. the observation of patients suffering from postinsult and noninsult variants of vascular parkinsonism have been carried out

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INFLAMMATION IN DEVELOPMENT OF CHRONIC CEREBROVASCULAR INSUFFICIENCY ATHEROSCLTROTIC DENESIS

Year: 2006, volume 2 Issue: №3 Pages: 29-33
Heading: Neurology Article type: Original article
Authors: PARSAMYAN R.R., ZACHAROVA N.B., VOSKRESENSKAY O.N.
Organization: Saratov State Medical University
Summary:

In this the changes of the level interleuikin-4, g interferon, tumor necrosis factor-a and C-reactive protein (CRP) of the patients chronic cerebrovascular insufficiency. The study included 67 patients aged 44 – 78 years. The dislipidemia and cytokines features of different stage of the disease were analyzed.

Ninetieth Anniversary of Parkinson’s Disease «Substantia Nigra» Theory

Year: 2009, volume 5 Issue: №2 Pages: 279-282
Heading: History of Medicine. Anniversary Dates Article type: Review
Authors: V.V. Yudina, N.S. Makarov, G.K. Yudina, L.A. Kabanova, O.N. Voskresenskaya
Organization: Saratov State Medical University
Summary:

Article is devoted to the Ninetieth Anniversary of Creation of the «substantia nigra» theory of Parkinson’s disease by famous Saratov scientist K. N. Tretjakov.

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REHABILITATION POTENTIAL AND ITS EVALUATION AT NERVOUS SYSTEM DISEASES

Year: 2009, volume 5 Issue: №1 Pages: 120-123
Heading: Neurology Article type: Review
Authors: J.N. Klemesheva, O.N. Voskresenskaya
Organization: Saratov State Medical University
Summary:

The article presents a review of literature, dealing with evaluation and usage of rehabilitation potential in neurologists’ clinical practice. Rehabilitation potential is a basis of invalids’ rehabilitation programs. The authors emphasize the importance of evaluation of rehabilitation potential in medical and social examination, taking into consideration its high prognostic value in the process of invalids’ biopsychosocial status of possible rehabilitation and his/her return to the social life.

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