Saratov JOURNAL of Medical and Scientific Research

Saratov State Medical University

www.sgmu.ru

Transfollicular drug delivery: current status of the problem

Year: 2018, volume 14 Issue: №4 Pages: 735-737
Heading: Dermatovenerology Article type: Review
Authors: Talnikova Е.Е., Svenskaya Yu.l., Dobdina A.Yu., Morrison A.V., /UtzS.R./
Organization: Saratov State Medical University
Summary:

The review is dedicated to one of the promising areas in medicine —transfollicular drug delivery. The article presents
literature data on working principles of this route of administration, main practical aspects and future prospects for its
use.

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Regional peculiarities of the morbidity of psoriasis and psoriatic arthritis

Year: 2018, volume 14 Issue: №4 Pages: 724-727
Heading: Dermatovenerology Article type: Original article
Authors: Nelyubova O.I., Sazanova G.Yu., Razdevilova O.P.
Organization: Saratov State Medical University
Summary:

Objective: to analyze the incidence of various forms of psoriasis in the population of the Saratov region for the period from 2009 to 2016 Material and Methods. We studied the indicators of the total and primary incidence of psoriasis in the adult population in the Saratov region for the period from 2009 to 2016 in comparison with similar indicators for the Russian Federation (RF), according to the Ministry of Health of the RF Results. It is revealed that for the period 2009-2016 the overall incidence of adult psoriasis in the Saratov region increased by 5.8%, in the RF by 13.8%; the overall incidence of adult psoriatic arthritis in the Saratov region increased by 8.1 %, in the RF by 2.2%; Primary morbidity of the adult population of psoriatic arthritis in the Saratov region increased by 11.4%, in the RF by 2.3%. Primary incidence of psoriasis for the period 2009-2016 among the adult population in the Saratov region decreased by 18.5%, in the RF by 45%, which also reflects the dynamics in the RF. Conclusion. The steady increase in the overall incidence of psoriasis and psoriatic arthritis in the adult population, the level of primary morbidity in psoriatic arthritis directly affects the costs and level of the state budget and requires ways to find ways to improve the organization of medical care of a dermatovenerological profile.

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Some epidemiological aspects of syphilis infection in the Saratov region (2007-2017)

Year: 2018, volume 14 Issue: №4 Pages: 715-719
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A., Bakulev A.L., Sherstobitova L.A., Martynova V.V.
Organization: Saratov State Medical University
Summary:

Aims: to study the epidemiological aspects of syphilitic infection and neurosyphilis in the Saratov region for the period 2007-2017. Material and Methods. On the basis of statistical materials of the state statistical observation for 2007-2017 the indicators of syphilis incidence are analyzed. Results. The analysis of the data obtained from the state statistical supervision forms during 2007-2017 has shown the decreasing tendency of number of newly reported cases of syphilitic infection. The indicators of morbidity caused by late syphilis and neurosyphilis have increased. The number of regional cases of syphilitic infection with involvement in the pathological process of the nervous system exceeds similar indicators in Russia, and late asymptomatic neurosyphilis prevails among clinical forms. Conclusion. In the Saratov region for the period 2007-2017 there is a decrease in the incidence of syphilis, which is accompanied by an increase in hidden forms of infection and neurosyphilis.

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Professor N. E. Kushev as a country doctor, a scientist, a teacher and a public figure (to the 160-th anniversary)

Year: 2018, volume 14 Issue: №4 Pages: 699-703
Heading: Scientific schools and memorable dates Article type: Case report
Authors: Zavyalov A.l., Petrov V.V., Kustodov S.V., Kravtsov O.A.
Organization: Saratov State Medical University
Summary:

The article presents biographical information about Professor N. E. Kushev. It describes his scientific and practical contribution to the development of native medicine at the turn of the XIX-XX centuries including the organization of malaria control, training of scientific and pedagogical staff at the medical faculty of the Saratov University and public activities.

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The 40th anniversary of Department of Clinical Laboratory Diagnostics of Saratov State Medical University

Year: 2018, volume 14 Issue: №4 Pages: 696-699
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Gladilin G.P., Zakharova N.B., Nikitina V.V., Ivanenko I.L.
Organization: Saratov State Medical University
Summary:

The article describes a brief history of the development of laboratory services and gives a modern idea of the importance of laboratory diagnostics in the clinic. The pedagogical, scientific activities and future prospects for the development of clinical laboratory diagnostics of the Saratov State Medical University are presented.

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Readiness to realize the skills of professional communication among senior students of a medical university

Year: 2018, volume 14 Issue: №4 Pages: 691-695
Heading: Sociology of Medicine Article type: Original article
Authors: Shemetova G.N., Sidorova N.V., Gubanova G.V.
Organization: Saratov State Medical University
Summary:

Aim: to assess the readiness for effective communication of senior students of medical university. Material and Methods. A survey of 158 students of the 5th and 6th courses of the medical faculty of SSMU was conducted in February 2017 according to the original questionnaire aimed at assessing the theoretical knowledge in the field of communication and readiness to communicate with patients in practice. Results. The study revealed a number of problematic issues related to the communicative competence of senior students of the medical University. Most respondents (88%) rated their training in communication technologies as high and sufficient, and knowledge of theoretical issues does not always meet the requirements of today. Despite the support of the majority of students for a paternalistic approach to the relationship between the doctor and the patient (44% in general, 94,7% among sixth- year students), many respondents (85%) agreed with the involvement of the patient in the process of discussing the planned diagnostic and therapeutic measures, more than half of the students (57,6%) expressed a desire to undergo additional training on the basics of communication. Conclusion. In accordance with the new challenges in the native health care training of graduates of medical universities should include the formation and improvement of communicative competence with the realization that in the modern system of relations the Central person is a patient with his problems and

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Medical and organizational issues of patients' preoperative fears management (analytical review)

Year: 2018, volume 14 Issue: №4 Pages: 686-690
Heading: Sociology of Medicine Article type: Review
Authors: Fedonnikov A.S., Katkova A.V., Andriyanova E.A.
Organization: Saratov State Medical University
Summary:

 The article deals with the problem of preoperative patient fears. Specific characteristics of preoperative fears and the mechanisms of their occurrence were described. According to the scientific literature analysis the typology of preoperative fears was performed. Within the framework of the author's approach the directions of the following theoretic understanding and practical solutions of indicated problem were presented. They included health managers focusing on interpersonal communication of patient and medical specialist; further analysis of factor influencing interpersonal communication of patient and medical specialist under disease condition requiring surgery; development of psychologically based medical care and postoperative rehabilitation quality indicators.

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Medical students representations on socially significant aspects of influenza prevention

Year: 2018, volume 14 Issue: №4 Pages: 680-682
Heading: Sociology of Medicine Article type: Original article
Authors: Mikhailova E.V., Malugina T.N., Levin D.Yu., Averianov А.Р., Serdyukov A.Yu., Zheleznikov P.A.
Organization: Saratov State Medical University
Summary:

The aim of the study is to assess the attitude to influenza prevention among medical students. Material and Methods. The survey of first-year students of Saratov State Medical University n.a. V. I. Razumovsky was conducted (n=110). Results included an analysis of the prevalence of different influenza prevention methods. We have identified the main causes of failures of specific influenza prevention and identified the most common ways of non-specific prevention. Conclusion. Despite the fact that the majority of students consider it necessary to carry out specific prevention of influenza, active immunization is used only by 15% of the surveyed students. Others prefer the methods of nonspecific prophylaxis of influenza.

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The value of tumor markers in prognos-ing the outcomes of treatment of patients with bladder cancer

Year: 2018, volume 14 Issue: №4 Pages: 661-666
Heading: Urology Article type: Review
Authors: Ponukalin A.N., Zakharova N.B., Skriptsova S.A., Fomkin R.N., Chekhonatskaya M.L.
Organization: Saratov State Medical University n.a. V I. Razumovsky, Scientific Research Institute of Fundamental and Clinical Uronephrology, Saratov State Medical University
Summary:

The review analyzes the recent publications of the results of the use of molecular genetic markers of bladder cancer (RMP) in clinical practice. The prospects of application of a series of molecules determined in tumor tissue, serum, urine in the diagnosis of RMP are presented. One ofthe most promising areas of finding a marker forthe diagnosis and control of treatment of RMP in recent years are the study ofthe proteomic composition of urine.

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Cortisol level as a marker of adaptation processes in children with acute respiratory viral infections

Year: 2018, volume 14 Issue: №4 Pages: 646-650
Heading: Infectious Diseases Article type: Original article
Authors: Malyugina T.N., Malinina N.V., Averianov А.Р.
Organization: Saratov State Medical University
Summary:

Aim: to study changes in the level of cortisol in children in the acute period of respiratory viral infection, depending on the etiology, severity of the disease and the presence and nature of the developed complications to establish an adaptation option. Material and Methods. 74 patients aged 1 to 10 years on day 1-3 from the beginning ofARVI (adeno-virus, parainfluenza, respiratory syncytial infection and mixed infection) and 15 healthy children were examined. The etiology ofARVI was established by PCR. Patients in the first three days from the beginning ofARVI were determined by the level of cortisol by the method, according to the indications, chest x-ray examination was performed. The type of adaptive response in children was determined by the value of the lymphocytic index and the level of cortisol in the blood serum. Results. The study showed that in children with ARVI there is a different reaction of the adrenal glands to the disease, which is characterized by both an increase and a decrease in their function. An increase in cortisol concentration characteristic of an adequate adaptation reaction was found in 59.2% of patients. In 12.3% of children noted a decrease in cortisol compared with the control group, in the remaining patients (28.5%) cortisol content did not differ from that in healthy children. Adaptation by the reaction type of "stress" alarm stage was observed in 37.1 % of children, the reaction of "stress" in the stage of resistance at 14.3% of patients, the reaction of "stress" with the development

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