Saratov JOURNAL of Medical and Scientific Research

Saratov State Medical University

www.sgmu.ru

Periodontal disease at cardiovascular pathology

Year: 2019, volume 15 Issue: №2 Pages: 246-251
Heading: Stomatology Article type: Review
Authors: Eremin A.V., Lepilin A.V., Lipatova T.E.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The purpose of the systematic literature review was to characterize existing problem of the relationship between cardiovascular diseases and periodontal diseases on the basis of information analysis of the Russian and English original studies and metanalyses published in open access bibliographical databases such as eLibrary and PubMed the past ten years as a methodological basis for future clinical and experimental studies

AttachmentSize
2019_02_246-251.pdf331.9 KB

Twin-to-twin transfusion syndrome: A clinical case

Year: 2019, volume 15 Issue: №2 Pages: 236-240
Heading: Pediatrics Article type: Case report
Authors: Nechaev V.N., Chernenkov Yu.V.
Organization: Saratov State Medical University
Summary:

At the heart of the development of twin-to-twin transfusion syndrome (TTTS) is the presence of pathological anastomoses in the placental vascular network. The article presents a clinical case of TTTS development in monochorionic twins with placental vessel abnormality with a diagnostic search and a plan of further management.

AttachmentSize
2019_02_236-240.pdf284.04 KB

Features of blood lipid profile in low birth weight infants with different types of feeding

Year: 2019, volume 15 Issue: №2 Pages: 232-236
Heading: Pediatrics Article type: Original article
Authors: Kadymova I.I., Bochkova L.G., Eiberman A.S., Gumeniuk O.I., Kirilochev O.K.
Organization: Astrakhan State Medical University, Saratov State Medical University
Summary:

The research goal is to study of blood lipid profile for different types of feeding in infants with low birth weight (LBW), very low birth weight (VLBW) and extremely low birth weight (ELBW) at birth, receiving breast milk or special mixes, to determine whether correction of their food. Material and Methods. The dynamic study of cholesterol (CS), triglycerides (TG), high-density lipoproteins (HDL) and low-density lipoproteins (LDL) was carried out depending on the type of feeding in low-weight infants of different weight categories. The concentration of these lipid components was determined using the test of Liquick Cor-CHOL; Liquick Cor-TG; CORMAY HDL DIRECT systems. Results. This study showed that newborns with extremely low birth weight with intrauterine growth retardation and newborns with very low birth weight had significantly lower levels of lipid profile than infants with low birth weight (CS — by 11-17%, TG — by 18-27%, HDL — by 33-47%, LDL— by 14%). Conclusion. Extremely low birth weight newborns with intrauterine growth retardation (IGR) and very low birth weight newborns need early correction of lipid metabolism throughout the neonatal period.

AttachmentSize
2019_02_232-236.pdf275.11 KB

Eradication therapy in children: the choice of the optimal treatment regimen

Year: 2019, volume 15 Issue: №2 Pages: 225-231
Heading: Pediatrics Article type: Review
Authors: Zryachkin N.I., Ananyeva O.V.
Organization: Saratov State Medical University
Summary:

The review is devoted to the choice of the optimal treatment regimen of eradication therapy in children. Main tasks in the treatment of children with gastroduodenal pathology associated with Helicobacter pylori are eradication of the pathogen, restoration of the damaged mucosa and prevention of recurrence of the infection. A particular importance in the composition of eradication schemes is the choice of antibacterial drugs. The main requirements for anti-Helico-bacter therapy regimens used in pediatric practice are: eradication rate of at least 80 %, economic accessibility, good tolerability with minimal severity of adverse reactions, optimal frequency of admission. An analysis of a number of domestic and foreign studies has shown that insufcient adherence of the patient to therapy, the presence of antibacterial resistance, pathogenicity factors in a number of strains of H. pylori have a negative efect on the efectiveness of treatment and should also be taken into account when choosing therapeutic tactics. Successful eradication of H. pylori in most cases depends on the optimal treatment regimen also has an impact on the result.

AttachmentSize
2019_02_225-231.pdf324.33 KB

Cardiac remodeling in patients with chronic kidney disease

Year: 2019, volume 15 Issue: №2 Pages: 217-221
Heading: Internal Diseases Article type: Review
Authors: Sedov D.S., Rebrov А.Р.
Organization: Saratov State Medical University
Summary:

The duration and quality of life of patients undergoing extracorporeal renal replacement therapy are largely dependent on concomitant diseases and conditions. Cardiovascular disease is a significant complication of chronic kidney disease and a major cause of death in patients undergoing hemodialysis. Cardiovascular remodeling is an independent predictor of the risk of cardiovascular events in patients with chronic kidney disease (CKD), including those in the dialysis stage. This paper analyzes the literature on left ventricular myocardial remodeling in the late predialysis stages of CKD and in patients receiving treatment with chronic hemodialysis.

AttachmentSize
2019_02_217-221.pdf306.44 KB

Clinical case of the manifestation of Parkinson's disease in a patient with neuro-leptic-induced parkinsonism

Year: 2019, volume 15 Issue: №1 Pages: 199-202
Heading: Neurology Article type: Case report
Authors: Yudina V.V., Makarov N.S., Yudina G.K.
Organization: Saratov State Medical University
Summary:

The article presents data on the mechanisms of development of drug-induced parkinsonism in patients taking neu-roleptic drugs, as well as on specifics of the development of Parkinson's disease in these patients. A clinical case of Parkinson's disease development in a patient with drug-induced parkinsonism who has been taken antipsychotics for a long time is described.

AttachmentSize
2019_01-1_199-202.pdf232.52 KB

Carotid arteries ultrasound screening in asymptomatic patients

Year: 2019, volume 15 Issue: №1 Pages: 190-199
Heading: Neurology Article type: Original article
Authors: Shchanitsyn I.N., Shvarts E.Yu., Ishmukhametova R.A., Vozdeeva A.S.
Organization: Saratov State Medical University
Summary:

Objective: to reveal the most important predictors of carotid artery stenosis in ambulatory patients of Saratov and Saratov Region with the help of multivariate analysis and to define an ideal patient for ultrasound screening. Material and Methods. In 2014-2018 off-site consultations and ultrasound screening were performed for asymptomatic patients with suspected carotid artery disease in outpatient clinics of Saratov and Saratov Region. Those patients were referred for screening by neurologists and general practitioners. The study used 470 medical charts. The multivariate regression analysis was performed to identify independent predictors of carotid artery stenosis (>50%). Results. The >30% carotid artery stenosis was detected in 24.5% (115/470) of participants, >50% stenosis — in 10.2% (48/470) of participants, >70% stenosis — in 2.9% (14/470) of participants. The multivariate analysis revealed that the odds of finding >50% stenosis in patients chosen by neurologists and general physicians for screening was significantly higher in the presence of following factors: age older then 72, male sex, acute cerebrovascular event more than 6 months ago, atherosclerosis in arteries of lower extremities, episodes of speech disorder. The point scale for risk assessment has been created. In the absence of prognostic factors the absolute risk of >50% stenosis was only 3%. In the presence of 1 point it was 16% and more than 50% in the presence of 4 points. Conclusion. The analysis we conducted allowed to specify major predictors of atherosclerosis in patients followed in outpatient clinics of Saratov and Saratov Region and to create the patient model which allows to optimize selection for ultrasound screening.

AttachmentSize
2019_01-1_190-199.pdf839.17 KB

Types of cephalalgia syndrome observed in medical students of Saratov State Medical University

Year: 2019, volume 15 Issue: №1 Pages: 177-179
Heading: Neurology Article type: Original article
Authors: Salina Е.А., Parsamyan R.R., Kuznetsova Е.В., Sholomov I.I., Uzhakhov A.M., Shichanina E.K.
Organization: Saratov State Medical University
Summary:

Purpose: to study the prevalence and clinical features of headache among medical students. Material and Methods. 160 students from the medical faculty on their 3rd and 6th years of education were surveyed. The type of headache was determined according to the International Classification of Headache (version 3, 2018). Neuropsychological status of students with tension headaches was studied with use of Schulte test, digital character substitution test, hospital anxiety and depression scale (HADS), test for determining sleepiness and sleep quality, tests for semantic and phonetic activity and memory. Statistical analysis was performed using MS Excel 2010 Results. The most common type of headache among medical students was primary headache, namely tension headache (78.2%). Migraine without aura (20.5%) and cluster headache (1.3%) were less common. Changes in the neuropsychological status were revealed in students suffering from tension headache. Conclusion. A study conducted among medical students showed a high prevalence of primary headache with a predominance of tension headache combined with anxiety and sleep disorders.

AttachmentSize
2019_01-1_177-179_1.pdf238.66 KB

Contribution of Saratov school of dermatology to the study of rare and chronic dermatoses in the 20-30s of the XX century

Year: 2019, volume 15 Issue: №1 Pages: 136-140
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Yakupov IA, Zavyalov Al, Utz SR, Morrison AV, Mizinov DS, Kryukov YuYu.
Organization: Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology of Moscow City Health Department, Saratov State Medical University
Summary:

The article is devoted to the scientific and practical contribution of the staff of the clinic of skin and venereal diseases of the Saratov Medical Institute in the study of etiology, pathogenesisand development of modern methods of diagnosis and treatment of rare and chronic skin diseases in the first half of the twentieth century.

AttachmentSize
2019_1_136-140.pdf236.99 KB

The activity of phthisiology service of the Saratov region during the Great Patriotic War and the first post-war years

Year: 2019, volume 15 Issue: №1 Pages: 132-136
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Chulochnikov А.А.
Organization: Saratov State Medical University
Summary:

The article presents a brief overview of the tuberculosis service's activities, of epidemiological situation in the Saratov region during the Great Patriotic war, and of contribution of advanced tuberculosis evacuation hospitals in reducing the number of tuberculosis cases among military personnel and civilian population in the Saratov region.

AttachmentSize
2019_1_132-136.pdf1.84 MB