Saratov JOURNAL of Medical and Scientific Research

Kudin M.V.

Saratov Ministry for Public Health, First Deputy Minister, Candidate of Medical Science

Enzymuria at children with nephropathy from developed cement industry region

Year: 2012, volume 8 Issue: №4 Pages: 965-970
Heading: Pediatrics Article type: Original article
Authors: Kudin M.V., Tzimbal D.E.
Organization: Volsk Central Hospital

For the purpose of enzyme morphological syndromes study enzymuria has been revealed in 58 children with nephropathy who live in the zones of cement industry and in 30 children with nephropathy from pure zones. Criteria of enzyme morphological characteristics have been estimated by enzymuria of enzymes: alkaline phosphatase, г-glutamyltransferase, leucine aminopeptidase, lactate dehydrogenase, cholinesterases. Research method of the enzymuria is kinetic by means of analyzers of reaction rate. In urine of children with nephropathy living in region with the cement industry, higher activity of enzymes, in comparison with group of conditionally pure zone, containing in a brush border — GGT in 1,9 times, LAP in 1,6 times, cytoplasmatic enzyme LDG — in 2,3 times has been established authentically. Results. Activity of AP and CE in urine of children of studied groups does not differ authentically. The revealed indicators of enzymuria can be served as markers of damage of proximal tubule of a nephron in children with nephropathy as a result of influence of echopathogen. Direct correlation has been determined between toxic microelements content in urine and biosphere and indicators of enzymuria in children.

201204-965-970.pdf792.71 KB

Ecogeochemical characteristics of region with advanced cement industry

Year: 2011, volume 7 Issue: №1 Pages: 026-030
Heading: Health Service Organization Article type: Original article
Authors: Kudin M.V.
Organization: Saratov Ministry for Public Health

Problems of biosphere pollution by toxicants and toxic chemical elements are considered to be actual issues. The research goal is to examine ecogeochemical condition in the cement industry. Quantitative chemical content of I -IV danger classes of chemical elements in soil has been determined by means of atomic-emission spectrometry method with specters excitation in inductive high-frequency discharge. The same research has been held in the conditionally clear zone. In advanced cement industry as compared with conditionally clear area toxic chemical element index has been found to be increased. The research results have proved environmental problems in this sphere

Keywords: ecotoxicants, cement
201101_026-030.pdf316.12 KB