Saratov JOURNAL of Medical and Scientific Research

Kovalenko Yu.V.

Saratov State Medical University n.a. V.I. Razumovsky Surgery and Oncology Institute of Additional Professional Education, Assistant

Sergey Ivanovich Spasokukotsky as a founder of Department of Hospital Surgery of Saratov State Medical University named after V.I. Razumovsky (to the 150th birth anniversary)

Year: 2020, volume 16 Issue: №2 Pages: 538-541
Heading: Scientific schools and memorable dates Article type:
Authors: Tsarev О.А., Kovalenko Yu.V., Zavyalov A.I., Titova D.A.
Organization: Saratov State Medical University
Summary:

The article presents the bibliographic data about academician S. I. Spasokukotsky. It demonstrates his contribution to the development of surgery, healthcare management and training of academic and teaching staff at Department of Hospital Surgery of Saratov Medical University.

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Legal aspects of medical services in the professional activity of a doctor

Year: 2020, volume 16 Issue: №1 Pages: 83-87
Heading: public health Article type: Author's opinion
Authors: Kovalenko Yu.V., Fomicheva R.V., Tolstokorov A.S., Kravchenya A.R., Titova D.A.
Organization: Saratov State Law Academy, Saratov State Medical University
Summary:

The substantiation of the need to improve the legal model of ensuring the safety of interaction between the patient and medical personnel in the provision of medical services is given. The study conducted a comparative legal analysis of the sources of legal regulation of individual components of the quality of medical services. The material for the assessment were articles of the Federal law "On the basis of health protection of citizens in the Russian Federation", as well as orders approved by the Ministry of Health of the Russian Federation. Proposals have been developed to improve the current legislation aimed at ensuring legal protection of medical personnel. On the basis of the conducted research it is established that there is no legal definition of quality of medical services. Existing laws protect the rights of patients, but the professional activities of medical personnel do not have a system of insurance of risks that create increased danger in the provision of medical care to the population.

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Efficacy of surgical treatment of renal form of hyperparathyroidism

Year: 2018, volume 14 Issue: №2 Pages: 265-267
Heading: Surgery Article type: Original article
Authors: Kovalenko Yu.V., Tolstokorov A.S., Rossolovsky A.N., Kravchenya A.R., Manakhov G.A.
Organization: Saratov State Medical University
Summary:

Objective: to study the efficacy of surgical treatment of primary hyperparathyroidism in risk of uronephrolithiasis progression. Material and Methods. The research involved 55 patients, the biochemical and clinical parameters before and after treatment with retrospective-prospective method of analysis were studied and analyzed. Results. It is established that the surgical treatment of patients with uronephrolithiasis is proved to be effective in 96,4% of the cases, as it allows to eliminate the classic symptoms of primary hyperparathyroidism, and urolithiasis. Improvement of laboratory hormonal and biochemical indices of mineral metabolism, and, consequently, reducing the severity of risk factors of urolithiasis is marked. Conclusion. Surgical treatment of renal forms of primary hyperparathyroidism is a pathogeneti-cally reasonable method. Parathyroidectomy performed in an adequate amount prevents relapses and progression of diseases that are the consequence of primary hyperparathyroidism.

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Primary hyperpara-thyroidism: current state of the problem

Year: 2017, volume 13 Issue: №4 Pages: 849-853
Heading: Surgery Article type: Review
Authors: Kovalenko Yu.V., Tolstokorov A.S., Rossolovsky A.N., Kravchenya A.R., Manakhov G.A., Velikanova M.G.
Organization: Saratov State Medical University
Summary:

 The review is devoted to current state of the problem of primary hyperparathyroidism. One of the important steps in the study of pathology of parathyroid glands and their decision value in development of primary hyperparathyroidism was introduction of automated screening of the ionized calcium of plasma of blood to all patients asking for medical care. Understanding of the nature of this process allowed the doctors of many specialities to unite the efforts in the analysis of results of the already accumulated experience and extend possibilities of early preclinical exposure of this disease.

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Clinical and morphological features of diagnosis and treatment of various forms of primary hyperparathyorosis

Year: 2017, volume 13 Issue: №3 Pages: 541-543
Heading: Surgery Article type: Original article
Authors: Kovalenko Yu.V., Tolstokorov A.S., Kravchenya A.R., Khubolov A.M., Manakhov G.A.
Organization: Scientific Research Institute of Traumatology Orthopedics and Neurosurgery of Saratov State Medical University n.a. V.I. Razumovsky
Summary:

Objective: optimization of the diagnostic algorithm and treatment methods for different clinical forms of the primary hyperparathyroidism. Material and Methods. The article presents the results of examination and operative treatment of 59 patients diagnosed with the primary hyperparathyroidism, such patients having symptoms specific for the disease or having no symptoms of the same. Results. We have not revealed intraoperative complications after surgical interference; laboratory findings have been normalized in 96.6% of cases. The patients having undergone the surgery have been followed up for 12 months with no relapse. 11.9% of the patients have been diagnosed with the asymptomatic primary hyperparathyroidism. Conclusions. Parathyroidectomy is the only radical and effective treatment for the primary hyperparathyroidism. Parathyroidectomy performed surgically to the proper extent, prevents the relapse as well as development of diseases resulting from the primary hyperparathyroidism.

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Experience of antireflux surgery application for the treatment of gastroesophageal reflux disease

Year: 2015, volume 11 Issue: №4 Pages: 583-586
Heading: Surgery Article type: Original article
Authors: Tolstokorov A.S., Khubolov A.M., Kovalenko Yu.V.
Organization: Saratov State Medical University
Summary:

Purpose of the study: post-hoc analysis of mid-term and late results of various types of antireflux surgery performed to treat hiatal hernia. Material and methods. We have studied results of post-surgery examination of 118 patients diagnosed with hiatal hernia, the examination being performed at various time intervals after surgeries. Results. The only benefits of using laparoscopic treatment include cosmetic effect, shorter terms of hospital stay and recovery of person's capacity to work. Conclusion. Analysis of immediate and late results of surgical treatment of gastroesophageal reflux disease as well as frequency of postsurgical relapses provided no certain evidence of significant beneficial effect for choosing laparoscopic surgical methods over traditional open surgery.

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Genetic aspects of etiology and development of thyroid gland cancer

Year: 2012, volume 8 Issue: №3 Pages: 854-858
Heading: Surgery Article type: Review
Authors: Kovalenko Yu.V., Tolstokorov A.S.
Organization: Saratov State Medical University
Summary:

Recent studies on thyroid gland cancer development and progression have identified new classes of tumor markers, proto-oncogenes, tumor-suppressing genes, cell receptor genes, identified genetic tumor-predisposing polymorphism and some other significantly important segments of genome. The identification has been based mainly on revealing of DNA abnormal consequences, specific for occurrence of thyroid gland cancer and its progression.

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Postoperative recurrent goiter: disease or complication (review)

Year: 2012, volume 8 Issue: №1 Pages: 152-158
Heading: Surgery Article type: Review
Authors: Kovalenko Yu.V.
Organization: Saratov State Medical University
Summary:

The histotypic structure of nodular growths has been morphologically studied after the primary surgery and reinter-vention. The revealed difference may indicate either the new thyroid tissue formation or the initial diagnosis error and inadequate surgery. Histological changes of the thyroid gland are caused by both the external (surgery, anthropogenic influence) and internal (reparative processes, dystrophic changes, hormone biosynthesis disturbance) factors, including iodine metabolism. It results in postoperative goiter development

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Postoperative recurrent nontoxic nodular (multinodular) goiter

Year: 2011, volume 7 Issue: №4 Pages: 975-980
Heading: Endocrinology Article type: Original article
Authors: Kovalenko Yu.V., Tolstokorov A.S.
Organization: Saratov State Medical University
Summary:

The extensive use of modern methods of examination (ultrasound investigation with Doppler mapping, aspiration (needle) biopsy, radiodiagnostics) cannot resolve the problem of verification of nodular mass in case of multinodular goiter before operation. Operative intervention is the method of choice in this case, which gives rise to the problem of surgery extent. The present study is useful in improvement of remote results of surgical treatment of multinodular goiter through statistical estimation of recurrent goiter development. The study was retrospective and included 102 consecutively admitted and operated patients with recurrent goiter and 102 patients of control group with first diagnosed and operated goiter. Patients of both groups were in euthyroid state. Patients were admitted to the Clinic of Surgery and Oncology of Raising Skills Faculty of Saratov State Medical University n.a. V. I. Razumovsky from 2000 till 2004. Statistical analyses included calculation of average mean, standard deviation and mean error. Student's ratio was used as the test of validity of average mean. Chi-square test was used for assessment of qualitative characteristics.

Keywords: thyroid status
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Punction methods of diagnostics and treatment of thyroid diseases

Year: 2010, volume 6 Issue: №2 Pages: 464-467
Heading: Surgery Article type: Original article
Authors: A.S. Tolstokorov, G.I. Yershova, Yu.V. Kovalenko, S.A. Dergunova
Organization: Saratov State Medical University
Summary:

The object of this research is to study the punction methods role under diagnostics and treatment of different thyroid diseases. The authors of this article present treatment methods of 121 patients with different thyroid diseases. The received results allow to draw a conclusion, that punction methods of diagnostics and treatment of thyroid disease can be used as independent methods of treatment and in a complex with other medication remedies

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