Saratov JOURNAL of Medical and Scientific Research

Original article

Some Peculiarities of Bone Tissue Remodelling at Hip Joint Inflammatory and Degenerative Diseases

Year: 2009, volume 5 Issue: №2 Pages: 227-230
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: E.V. Karyakina, E.A. Persova
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

During the assessment of peculiarities of bone tissue remodelling in inflammatory and non inflammatory lesions of hip joint, according to the levels of biochemical indices in the blood serum, some unilateral changes of bone tissue metabolism have been revealed in advanced rheumatoid arthritis and osteoarthrosis. More severe disturbances of bone remodelling in case of rheumatoid arthritis are obviously connected with peculiarities of the rheumatoid inflammation pathogenesis.

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Epstein-Barr Viral Infection in Children: Cytokine Response Peculiarities and Immunopathological Reactions

Year: 2009, volume 5 Issue: №2 Pages: 222-226
Heading: Infectious Diseases Article type: Original article
Authors: S.A. Khmilevskaya, I.A. Zaytseva, E.V. Mikhaylova
Organization: Saratov State Medical University
Summary:

The research results are presented in the work. 100 patients aged 1–18 with different Epstein-Barr viral infection course variations have been observed. Clinical features of infectious mononucleosis in case of primary infection and its revivification have been revealed. The evaluation of intensity of autosensibilization processes has been performed. The interrelation of autoimmune and cytokine reactions and their participation in formation of organopathology in case of Epstein-Barr viral infection are demonstrated.

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The Influence of Retinalamine on the Myopic Process in Schoolchildren

Year: 2009, volume 5 Issue: №2 Pages: 218-221
Heading: Ophtalmology Article type: Original article
Authors: K.Yu. Yeremenko, L.E. Fedorischeva, N.N. Aleksandrova
Organization: Saratov State Medical University
Summary:

The paper presents results of complex treatment of 422 children with myopia of various degrees aged from 7 to 17 years. The main group included 265 children: 124 patients with myopia, 141 — with myopia and Computer Visual Syndrome (CVS) and 78 children with anisometropia. The control group consisted of 157 patients. 1% Emoxipine and 4% Taufone were used in children of the control group.
Modern methods of examination showed more effective influence of Retinalamine on the visual functions. The incorrective and corrective visual acuity and the volume of accommodation were increased. At the same time the therapy helped to decrease the angle of deviation. Tiredness and asthenopia disappeared in children with CVS. The positive treatment effect was stable during 10–16 months.

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The Organism Functional Status of Navy Helicopter Pilots and the Ways of its Optimization

Year: 2009, volume 5 Issue: №2 Pages: 212-217
Heading: Military medicine and disaster medicine Article type: Original article
Authors: D.L. Kotliar, A.N. Onishchenko
Organization: Saratov Military Medical Institute
Summary:

The results of the study of the organism functional status of navy helicopter pilots and navigators in different situations and working conditions of the professional activity (i.e. marine trip, during the preparation and realization of flights at the base airfield) have been analyzed in the process of military professional adaptation. The high physiological “value” of the specific pilots’ labor has been estimated. The technology of organism functional status optimization for helicopter pilots that takes into account psycho-physiological specifity of the professional activity as well as a revealed regularity in organism functional status changes and military professional adaptation has been worked out. That constitutes the sum total of physiologically proved structural and functional components, that is adaptation improvements, correction of the functional state restoration at the base airfield, working out recommendations for ship doctors on flying staff functional status individual correction during marine trip.

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Functional Diagnostics Methods Comparative Assessment In Determination Of Different Diastolic Dysfunction Types

Year: 2009, volume 5 Issue: №2 Pages: 207-211
Heading: Internal Diseases Article type: Original article
Authors: S.A. Mironov
Organization: Ministry of Defense of the RF, State Institute for Advanced Training of Physicians
Summary:

Analysis of transmitral flow criteria has been used to underestimate diastolic dysfunction degree. The study goal was to compare the evaluation of different echocardiographic methods to determine diastolic dysfunction types. There were 120 patients with chronic cardiac insufficiency under the study; control group included 30 healthy individuals. Pulmonary venous flow, transmitral flow at rest in carrying out Valsalva test and tests with isometric exercise have been examined for verification of diastolic dysfunction type by Impulse Doppler Echocardiographic Method. The findings have been compared with the results of Tissue Doppler Echocardiography.
Among patients with diastolic dysfunction type I according to the transmitral flow examination there were 22 (34%) with diastolic dysfunction type II using Tissue Doppler Echocardiographic method. Besides, 6 persons with diastolic dysfunction type III demonstrated no diastolic dysfunction signs according to the transmitral flow data. The Valsalva test enabled differentiation of diastolic dysfunction type II in only 39% of all cases while test standardization increased the method’s value up to 55%. The isometric exercise test for diastolic reserve indication may be compared by its effectiveness with Tissue Doppler Echocardiographic method used for detection the diastolic dysfunction restrictive types.

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Chronic Biliary Pancreatitis Clinical Course Interrelation with Quality of Life and Patients Dependance on Supporting Therapy Indices

Year: 2009, volume 5 Issue: №2 Pages: 203-207
Heading: Internal Diseases Article type: Original article
Authors: E.I. Khashkina, J.V. Listishenkova
Organization: Saratov State Medical University
Summary:

The analysis of clinical course influence on life quality and patients dependance on supporting therapy of chronic biliary dependent pancreatitis is represented. It has been determined that increase of life quality is in close correlation with exacerbation frequency, dyspepsia syndrome evidence and manifestations of exocrinous insufficiency of pancreas. Patients with chronic biliary dependent pancreatitis do not carry out doctor’s recommendations in appropriate manner.

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New Routs In Optimization Therapy of Helicobacter Pylori Eradication in Patients with Chronic Duodenal Ulcer

Year: 2009, volume 5 Issue: №2 Pages: 200-203
Heading: Internal Diseases Article type: Original article
Authors: V.V. Dugina, N.S. Khruleva
Organization: N. Novgorod State Medical Academy
Summary:

Pharmacological effects of immunomodulators produce normalization of immunochemical function of homeostasis. This phenomenon determines optimization of Helicobacter pylori eradication. The combination of immunomodulators with antibiotics has a double effect. Antibiotics destress the functional activity of microorganisms and increase it’s sensitivity to the effect of phagocytes. On the other hand immunomodulators increase functional activity of phagocytes to eliminate microorganizms Оptimization of Helicobacter pylori eradication by using of immunomodulators is necessary for clinical practice. It includes prophylaxis of recurrences and complications caused by drugs action on immune system in patients with chronic diseases.

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Gender And Age Peculiarities Of Tobacco Addiction Among The Urban Population Of The Middle Volga Region

Year: 2009, volume 5 Issue: №2 Pages: 197-200
Heading: Internal Diseases Article type: Original article
Authors: S.A. Babanov, I.A. Agarkova
Organization: Samara Polyclinic №1, Samara State Medical University
Summary:

On the basis of the conducted research, prevalence of tobacco smoking and its intensity according to the gender and age descriptions among the urban population in the Middle Volga region (Samara as an example city) is described in the article. It is proved, that among men and women under study 49,37% and 14,17% smoke accordingly, 22,80% and 8,86% smoked before, 27,83% and 76,97% never smoke. The education level and family status have considerably contributed to the epidemiology of tobacco smoking addiction. Authors consider, that the development of public and medical measures directed to the fight against smoking must be realized taking into account the gender, age, social and mental points, that is difficult, but necessary process.

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Medication and Plasmapheresis Efficacy in Bronchial Asthma Combined with Arterial Hypertension

Year: 2009, volume 5 Issue: №2 Pages: 194-197
Heading: Internal Diseases Article type: Original article
Authors: T.G. Shapovalova, T.V. Stepanova, S.B. Smolyak
Organization: Saratov Clinical Hospital N 8, Saratov State Medical University
Summary:

Expiration function, cardiohemodynamics and blood viscosity indices have been investigated in 178 patients in order to evaluate the efficacy of plasmapheresis application in complex therapy of acute bronchial asthma combined with arterial hypertension. Complex therapy proved to be advantageous.

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Data Of Daily Blood Pressure Monitoring In Patients With Rheumatoid Arthritis

Year: 2009, volume 5 Issue: №2 Pages: 190-164
Heading: Internal Diseases Article type: Original article
Authors: N.M. Nikitina, O.S. Lobanova, A.P. Rebrov
Organization: Saratov State Medical University
Summary:

The aim of present work is to study the frequency of hypertension and the peculiarity of 24-hour blood pressure monitoring in patients with rheumatoid arthritis. We studied 584 patients with rheumatoid arthritis. Daily blood pressure monitoring was carried out in 46 patients with arthritis and 18 patients with essential hypertension. Frequency of hypertension was higher in patients with arthritis then in general population. Elevation of systolic blood pressure, heart rate and arterial blood pressure adequate decrease at night were developed to associate with advance of the disease.

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