Saratov JOURNAL of Medical and Scientific Research

Original article

Age-Specific and Sexual Variability of Morphological and Biomechanical Parameters of the Basilar Artery of Adult People

Year: 2009, volume 5 Issue: №2 Pages: 159-163
Heading: Macro- and Micromorphology Article type: Original article
Authors: O.A. Fomkina, V.N. Nicolenko
Organization: Saratov State Medical University
Summary:

For the purpose of studying of morphological and biomechanical parameters of the basilar artery in an experiment on monoaxonic distension by tensile-testing machine Tira Test 28005 (Germany) with a loading cell — 100 N we determined general solidity, breaking point, maximum and relative deformation of the artery. Preliminary under a microscope on cross-section cuts we measured the external diameter of the artery, its wall thickness and calculated the diameter of the lumen. In total, 114 basilar arteries (66 — from corpses of men, 48 — from corpses of women) have been investigated. They were received not later than 16 hours after autopsy of adult people, whose cause of death has not been connected with a sharp vascular cerebral pathology. The statistically authentic prevalence of the size of wall thickness and general solidity of the men’s artery wall was revealed. In age aspect the external diameter, the lumen diameter and the wall thickness of the basilar artery increase. At the same time the solidity of the wall decreases and its ability to prolongation increases.

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Structure Of Muscular Parts of Interventricular Septum of the Heart Human Fetal

Year: 2009, volume 5 Issue: №2 Pages: 155-159
Heading: Macro- and Micromorphology Article type: Original article
Authors: A.A. Yakimov
Organization: Uralsk State Medical Academy
Summary:

Interventricular septum (IS) has been studied in ordinary formed human fetal hearts (20–28 weeks) by means of the anatomo-metrical method. VS breadth appears to be less than its length, but is more than the breadth of the medial walls of both ventricles. The outlet length surpasses the inlet one more on the right than on the left septal side. On transversal sections the angle between IS departments is 122 — 139°. The angle degree increases from the basis to the apex of the heart. The angle between the longest axes of the right surface divisions is 38 — 42°. The length proportions of the IS departments become constant to the middle fetal period. The sinus part of the IS is square or multiangular (often four- or five-angular) and along the bloodstream. The development of the sinus part is coordinated with formation of the inlet trabecular part. The conal part is the smallest one. The conal development in the middle fetal period has not been completed yet. Size proportions of the IS parts and departments seem to be much the same in the normal fetal and newborn hearts.

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Hepatic Vessels Condition in Experimental Pulmonary Trunk Stenosis With Different Level of Blood Circulation Compensation

Year: 2009, volume 5 Issue: №2 Pages: 151-155
Heading: Macro- and Micromorphology Article type: Original article
Authors: S.V. Kulikov
Organization: Yaroslavl State Medical Academy
Summary:

Hepatic changes have been studied in 25 pupies with modeled stenosis with compensation and 8 animals with decompensated stenosis of pulmonary trunk. For controlling we have used liver of 10 dogs of the same age. Material has been tested by hystological, morfometric and stereometric mesurements. We have figured that after pulmanory trunk stenosis and the decrease in circulation of hepatic venous blood tonus of arteries increases, reflectory and resistance to circulation grows. Except venous-arterial reactions in incoming vessels small boundles of oblique intimal muscular system, muscular-elastic sfincters, polipsimillar pillows have been formed and in outcoming vessels muscular structures hypertrophy.has been indicated In case decompensated stenosis with hypoxia relaxation of outcoming and outgoing vessels happens, the quantity of arteries with adapting structures decreases, and muscular formations of hepatic veins atrophy.

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Pathological Anatomy and Quantitative Analysis of morphologic dimensions of 1-Year Old Children Hearts in Case of Sudden Death at Home

Year: 2009, volume 5 Issue: №2 Pages: 148-150
Heading: Macro- and Micromorphology Article type: Original article
Authors: Yu. R. Yunusova
Organization: Samara State Medical University
Summary:

One hundred twenty-three babies died at home at the age of 1–12 months have been examined from 2004 till 2008. 39 babies died from sudden infant death syndrome (SIDS). The comparison group has been composed of 58 babies of the same age died at home from various diseases. Investigations have been performed in DGCB N1, Samara. About 95 % of babies died from SIDS at home during the first six months of their life, with top mortality between 1 till 3 months. There was sexual difference — 67 % of boys. The majority of home death cases have happened in summer — 49 babies (30%). Morphological investigations have been made including different heart weighting, histological and histometric examination of cardiomyocites. It has been revealed that in the group of babies died from SIDS the most constant symptoms have included: right heart hypertrophy, great heart weight variability, ventricular index.

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Expression of Retinaldehyde Dehydrogenases (Raldh) – Enzymes that Catalyzate Retinoid Acid Synthesis in Mammalian Tissues During Early Embryonic Eye Development

Year: 2009, volume 5 Issue: №2 Pages: 145-147
Heading: Macro- and Micromorphology Article type: Original article
Authors: S.L. Kuznetsov, A.O. Molotkov
Organization: First Moscow State Medical University n.a. I.M. Sechenov
Summary:

Retinoid acid (RA) plays an important role in the regulation of early embryonic development and in particularly in eye development. To reveal possible influence of RALDH — enzymes on RA synthesis in mamalian tissues, in supplying RA for the eye development we have studied expression of these enzymes during early eye formation. The investigations enabled to find out that all three RALDH (RALDH 1, 2 and 3) are expressed during eye development in unique non-overlapping patterns, which correlate with RA activity in the same tissues. Thus it presents important role of these enzymes for providing RA in the eye development.

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CHANGE CHARACTERISTICS BLOOD FLOW UTERINE BEFORE LABOR

Year: 2008, volume 4 Issue: №2 Pages: 67-70
Heading: Obstetrics and Gynecology Article type: Original article
Authors: M.L. Chekhonatskay, I.E. Rogozhina, N.E. Yannaeva
Organization: Engels Perinatal Centre, Saratov State Medical University
Summary:

The article deals with research findings of uterus and uterus cervix blood flow in 120 healthy pregnant women in 37-42 weeks gestation period by transabdominal and transvaginal ultrasonic determination. The researches carried out have revealed marked interrelation between characteristics of uterus blood flow changes and the date of labor. In the last two weeks of gestation there is an intensification of uterus cervix blood supply and before labor there is a filling of uterus cervix with blood due to the increasing of venous vessels number and volume

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PROTEIN C ROLE IN MICROCIRCULATION DISTURBANCE IN PATIENTS WITH GINGIVITIS

Year: 2008, volume 4 Issue: №2 Pages: 61-63
Heading: Physiology and Pathophysiology Article type: Original article
Authors: V.F. Kirichuk, T.V. Simonyan
Organization: Saratov State Medical University
Summary:

The research purpose is focused on studying the role of protein С system in coagulation component disturbance of hemostasis and fibrinolysis system in patients with different forms of gingivitis.
The decrease of protein С and antithrombin inactivity, the decrease ofplasminogen reserve in blood, thrombin time shortening and the resistance of factor Va Via to protein Care watched in patients with different forms of gingivitis. The most marked changes in protein С system may be observed in exacerbation phase of acute and chronic ulcerative generalized gingivitis and chronic catarrhal generalized gingivitis. The reduction of indices of protein С system doesn’t occur in remission phase except in patients with chronic catarrhal ulcera five generalized gingivitis

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THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS

Year: 2008, volume 4 Issue: №2 Pages: 56-60
Heading: Microbiology Article type: Original article
Authors: N.G. Khodakova, G.M.Shub, I.G.Shvidenko
Organization: Saratov State Medical University
Summary:

Staphylococci playa great role in the emergence of various human illnesses. The most actual are infections caused by methicillin-resistant staphylococci.
The study of methicillin susceptibility as a polyresistance marker includes the definition of the minimum inhibitory concentration (MIC) of antibiotic which in vitro fully suppresses the visible growth of microorganisms in the standard experiment conditions and is expressed in absolute figures (mg/l or mkg/ml).
The aim of the research is the measure of MIC methicillin (oxacillin) for the clinical strains of staphylococci isolated from different clinical specimens and comparative analysis antibiotic’s MIC for Staphylococcus aureus and coagulase-negative staphylococci (CNS).
The resultofthe research is the determination of the oxacillin concentration preventing growth of the methicillin-resistant clinical strains ofS.aureus and CNSwhich were detected from different profile hospitals of Saratov- general hospital №2, maternity hospital №6, children’s regional hospital and centre ofcombustiology.
The methicillin-resistant of the staphylococci clinical strains in the Saratov region has not been investigated before.

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LOW-INVASIVE SURGICAL TREATMENT OF ACUTE CHOLECYSTOPANCREATITIS IN PATIENTS OVER 60

Year: 2008, volume 4 Issue: №3 Pages: 118-120
Heading: Surgery Article type: Original article
Authors: A.L. Charyshkin, O.V. Midlenko, I.I. Midlenko, E.G. Evtushenko, V.Yu. Schyogolev, A.V. Smolkina
Organization: Ulianovsk City Clinical Emergency Hospital, Ulianovsk Ministry of Health, Ulianovsk Regional Hospital № 2, Ulyanovsk State University
Summary:

Since 1998 to 2007 in the clinic of hospital surgery (based on surgical wards) of Ulianovsk State University the following types of surgical treatmentofpatients with cholelithic disease were carried out: more than 2000 laparoscopic cholecystectomies, 154 mini-laparotomies and 173 traditional laparatomies. Low-invasive surgical treatment of acute cholecystopancreatitis of patients over 60 years due to miniacess is advisable for persons with high degree of operationally anesthetic risk.

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FEATURES OF SURGICAL TACTICS AND TREATMENT OF ACUTE APPENDICITIS AT PRESENT STAGE

Year: 2008, volume 4 Issue: №3 Pages: 111-118
Heading: Surgery Article type: Original article
Authors: S.S. Slesarenko, A.Yu. Lisunov
Organization: Saratov State Medical University
Summary:

This research is dedicated to the problem of choosing treatment tactics in catarrhal form of acute appendicitis. The results of investigation and treatment of 1468 patients with acute appendicitis of our region were analyzed. Large specific gravity (26%) of patients who had been operated with regard to acute appendicitis was exposed. With the purpose of improvement of surgical treatment results of patients with acute appendicitis we have worked out and instilled a diagnostic system, which is a totality of invasive and uninvasive methods of investigation that allows to divide clinical material into two categories: one of them is with existence of inflamed process and the other is without it.

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