Saratov JOURNAL of Medical and Scientific Research

biomechanics

Computer modeling of biomechanical systems «femoral bone — endoprosthesis / transplant — tibia» in different methods of anterior cruciate ligament plastics in knee joint

Year: 2017, volume 13 Issue: №3 Pages: 764-768
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Shormanov A.M., Ivanov D.V., Norkin A.l., Ulyanov V.Yu., Bakhteeva N.Kh., Klimov S.S., Chibrikova Yu.A.
Organization: Saratov State Medical University
Summary:

The aim: to specify the indices of dislocation (displacement) and effective stress in biomechanical systems «femoral bone — endoprosthesis / transplant — tibia» in different methods of anterior cruciate ligament by computer modeling of a knee joint geometrically, physically and mechanically similar to human. Material and Methods. Steady-state tasks of the stress given on a knee joint after anterior cruciate ligament plastics fulfilled by different methods were resolved numerically by the method of finite elements implemented in the system of finite element analysis. Results. Maximum dislocations comprised 3.45 mm. for the method of single-beam plastics of ACL, 0.35 mm. for two-beam plastics and 0.93 mm. for plastics with semi-tendinous and gracilis tendons. Maximum stress were 1190 MPa for single-beam plastics of ACL, 141 MPa for two-beam plastics and 150 MPa for plastics with semi-tendinous and gracilis tendons. Conclusion. Finite element modeling of different ways of ACL plastics indicates higher stability of synthetic endoprosthesis under rising stress in case of two-beam plastics and transplant of semi tendinous and gracilis tendons compared to the single-beam plastics.

AttachmentSize
2017_03-2_764-768.pdf2.11 MB

Computer modeling of the system "bone — hybrid anchor" for proximal humerus fracture and scientific numeral outcomes for basic loads

Year: 2017, volume 13 Issue: №3 Pages: 738-742
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Kauts О.A., Barabash А.Р., Barabash Ju.A., Grazhdanov К.А., Rusanov A.G., Ivanov D.V.
Organization:
Summary:

The aim: to study the indices of stress-deforming state of biomechanical system «bone — hybrid anchor» in proximal humerus fractures. Material and Methods. The study of anchorage stiffness in juxta-articular fracture (type 11A3 by AO/ASIF) through applying three load types: axial (200 N), transverse (30 N) and torsional (5 N*m) was conducted followed by CAD modeling in SolidWorks and the analysis of stress-deforming state of the system «bone — anchor». Results. While studying the stability of «bone — anchor» system it was found that a new device for proximal humerus fracture ostheosynthesis under the applied loads do not decompose with maximal translocations of bone fragments and maximums of equivalent stress being present under torsional load and comprise 1.6 mm. and 152 Mpa respectively. Conclusion. The application of hybrid devices for juxta-articular fractures of humerus allows carrying out minimally traumatic anchorage with the following early functionality of the injured segment.

AttachmentSize
2017_03-2_738-742.pdf1014.21 KB

Changes in internal architectonics of proximal femur in children with hip dysplasia development

Year: 2014, volume 10 Issue: №4 Pages: 635-638
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Dokhov M.M., Barabash A.P.
Organization:
Summary:

The aim of the research is to identify common patterns of compensatory changes in internal architectonics of the proximal femur with valgus and varus deformity. Material and Methods. The parameters of the proximal femur were determined on the basis of 78 roentgenograms of children with hip dysplasia (1-4 years, 4-7 years, 7-16 years) before and after surgical treatment (after 6 months). Results. The degree of change in internal architectonics of the bone substance has been determined after changing of the femoral neck-shaft angle achieved with the help of correcting osteotomy in different age groups. Conclusion. Maximum recovery of internal architectonics of the bone substance is observed in the groups aged 4-7 years.

AttachmentSize
2014_04_635-638.pdf982.6 KB

Studies of pathological changes in mitogenetic signal pathways in cells in cancer patients using OncoFinder software package

Year: 2013, volume 9 Issue: №4 Pages: 775-780
Heading: Genetics Article type: Original article
Authors: Korzinkin М.В., Smirnov Ph.Yu., Venkova L.S., Krupnov A.V., Kuzmina N.B., Zhestkov B.G., Ivanova E.N., Buzdin A.A., Borisov N.M.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency, RAS Institute of Bioorganic Chemistry
Summary:

Although the basic components of a plethora of mitogenic, pro- and antiapoptotic etc. signaling pathways had been thoroughly studied and summarized during a couple of past decades, the particular pattern of changes for a given cancer patient has not yet been at the focus of a special research until now. Here we suggest the possible method of
the examination of the different malignant processes influencing the intensity of pro- and anti-mitotic signaling. According to our approach, first the tumor sample (that is taken from an individual patient) is studied using mRNA microarray technique, when the expression levels (normalized by the averaged value for the same intact organ/tissue for the same population) for several thousands of genes in the malignant cells is measured. Second, these expression levels are used to calculate the summarized values of pathological changes in mitogenic signaling pathways.

AttachmentSize
2013_04-01_775-780.pdf587.19 KB

Biomechanical evaluation of fixation degree of fragments by periosteal osteosynthesis

Year: 2010, volume 6 Issue: №3 Pages: 683-687
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Barabash Yu.A., Skripkin S.P., Grazhdanov K.A.
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

Expansion of indications for surgery and plate osteosynthesis of long bones points to increased number of complications caused by instability of fragments, that can be associated in their turn with constructive features or iatrogenic factors. Insufficient rigidity of fragment fixation is due to incorrect technical treatment and wrong choice of fixator. Biomechanical parameters of periosteal fixation rigidity have been experimentally proved, depending on fixator lever

AttachmentSize
201003_683_687.pdf350.02 KB

Fixation of periarticular fractures of proximal femur on biomechanical basis

Year: 2010, volume 6 Issue: №2 Pages: 411-414
Heading: Traumatology and Orthopedics Article type: Original article
Authors: A.P. Barabash, O.A. Kauts, Yu.A. Barabash, A.G. Rusanov
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

In the work comparison of two methods of pertrochanteric fracture fixation has been carried out: external one, with the help of the transosseous device and immersed one, by the dynamic femoral system. The investigation of the process of dislocation of fragments has been done on biophantomes. The dynamic compression in the external fixation device increases stability of the biomechanical system «bone-fixator» in 3-4 times. The use of single-stage fracture compression with dynamic femoral system allows to create stable fixation of fragments, adequate for early mobilization of patients

AttachmentSize
201002_411_414.pdf505.49 KB