Saratov JOURNAL of Medical and Scientific Research

Dudaeva N.G.

Saratov State Medical University n.a. V.I. Razumovsky, Department of Therapy of Raising^ Skills Faculty,, Assistant, Candidate of Medical Science

Geroprotective nutritional options (review)

Year: 2020, volume 16 Issue: №1 Pages: 168-171
Heading: Тhematic supplement Article type: Review
Authors: Lukyanov V.F., Dudaeva N.G., Satarova T.G.
Organization: Regional Hospital for War Veterans, Saratov, Saratov State Medical University

A literature review analyzes published data on geroprotective nutritional options. Nutrition is one of the fundamental factors that determine longevity and quality of life. Intestinal microbiota and its changes in the elderly and long-livers are being actively studied. The food selection and the calorie intake are directly related to the formation of microbiota.

2020-01-1_168-171.pdf291.85 KB

Cardiovascular risk factors and arterial stiffness in patients with ulcerative colitis

Year: 2019, volume 15 Issue: №3 Pages: 753-757
Heading: Cardiology Article type: Original article
Authors: Lipatova Т.Е., Mihailova Е.А., Dudaeva N.G.
Organization: Saratov State Medical University

Purpose: to assess cardiovascular risk factors and arterial stiffness in patients with ulcerative colitis (UC) without clinical manifestations of cardiovascular diseases. Material and Methods. 76 patients with remission of UC, 40 patients with irritable bowel syndrome and 25 healthy volunteers of comparable age and gender were examined. The 10-year risk of fatal cardiovascular events (SCORE) was calculated. Daily monitoring of arterial stiffness, endothelium function together with its vasodilative, vasoconstrictive and adhesive functions were evaluated in all examinees. Results. Traditional cardiovascular risk factors such as hypercholesterolemia, obesity or hypertension were not typical for patients with UC. Risk SCORE was low in the majority of UC patients. Patients with UC were characterized by the increase of intima-media complex thickness, C-reactive protein level, and by the decrease of HDL cholesterol. UC patients demonstrated the increase of arterial rigidity and endothelial dysfunction which reflected in statistically significant decrease of endothelium-dependent vasodilation to 11.48%, and increase of plasma levels of endothelin-1, vascular adhesion molecules VCAM-1 and ICAM-1. Conclusion. UC patients need multidisciplinary approach to study their arterial rigidity and markers of endothelial dysfunction.

2019_03-1_753-757.pdf320.85 KB

Science-based healthcare organization for Great Patriotic War veterans

Year: 2015, volume 11 Issue: №1 Pages: 015-019
Heading: 70 Years of Victory in the Great Patriotic War Article type: Original article
Authors: Lipatova Т.Е., Denisova Т.Р., Shuldyakov V.A., Yuanov А.А., Dudaeva N.G.
Organization: Regional Hospital, Regional Hospital for War Veterans, Saratov, Saratov State Medical University

The article summarizes the results of healthcare management of Great Patriotic War veterans for the last 20 years. This period included approbation and improvement of high-technology science-based and efficient healthcare system for war veterans. Healthcare managerial, medical and diagnostical activities are based on original analytical development including population system approach, biophysical approach to human organism, ageing, and senile and stress-induced disorders.

2015_01_015-019.pdf513.45 KB

Immunological and morphological aspects of diagnostics of Helicobacter pylori infection and Herpesviridae viruses

Year: 2010, volume 6 Issue: №2 Pages: 360-364
Heading: Infectious Diseases Article type: Original article
Authors: N.G. Dudaeva, V.B. Grechushnikov, I.O. Bugaeva, G.N. Tarasova, T.V. Golovacheva
Organization: Saratov State Medical University, Rostov State Medical University, Moscow Central Hospital № 6, Head of Endoscopic Ward

100 patients with inflammatory diseases of gastrointestinal tract were examined. Microbial component of inflammation process was detected by means of polymerase chain reaction (PCR). By means of PCR etiological microbial factor of mononuclear cells in peripheral blood (MCPB) was investigated. Mixtinfication of mucosa membrane of gastrointestinal tract with H. pylori and Herpesviridae in pathology of gastroduodenal area and presence of fragments of microorganisms DNA in PBMC were revealed. This phenomenon may be important in pathogenesis of pathology of gastrointestinal tract and forms the basis for its further investigation

201002_360_364.pdf407.9 KB