Saratov JOURNAL of Medical and Scientific Research

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A standardized approach to the choice of basic surgical treatment for large macular holes

Year: 2020, volume 16 Issue: №2 Pages: 687-690
Heading: Ophtalmology Article type: Short message
Authors: Chuprov A.D., Kazennov A.N., Mambetova Е.М.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

The purpose of the study is to optimize the choice of tactics for surgical treatment of large macular holes. Material and Methods. Analysis of the surgical treatment of macular holes in 18 patients (18 eyes) was performed. Patients were divided into 3 groups. Group 1 (8 eyes) included patients with a hole diameter of up to 500±22 urn, group 2 (6 eyes) — with a diameter of up to 800±20 urn, and group 3 (4 eyes) — over 800 urn. In group 1 vitrectomy was performed with peeling of the inner border membrane (IBM), application of platelet rich plasma (PRP) mass and tamponade with air; in the group 2 vitrectomy was performed with IBM peeling, application of PRP mass or closed with a free inverted IBM flap and tamponade with SF6 gas; in group 3 vitrectomy was performed with IBM peeling and closing of the macular holes was performed using a free inverted IBM flap with silicone oil tamponade. Results. There was complete closure of the macular holes with the formation of a normal fovea profile and improvement of visual acuity in all cases of group 1. In group 2 (PRP application) in 2 cases of 6, a second intervention was required with the"plasty" of the macular hole using an inverted IBM flap. In group 3, in 1 case, the gap did not close and in 1 more case it closed with a defect at the level of the ellipsoid zone of the photoreceptors. Conclusion. The preliminary results' analysis showed the effectiveness of the developed algorithm for surgical treatment of macular holes, depending on their diameter, which is optimal and allows obtaining the required anatomical and functional result.

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The use of autologous conditioned plasma in the surgery of cicatricial stage of choroidal neovascular membrane

Year: 2020, volume 16 Issue: №2 Pages: 569-572
Heading: Ophtalmology Article type: Short message
Authors: Arsyutov D.G.
Organization: Republican Clinical Ophthalmologic Hospital, Сhuvashia
Summary:

The purpose of the study is to estimate the effectiveness of the cicatricial stage of choroidal neovascular membrane surgery with retina fixation after retinotomy of paracentral areas with the use of autologous conditioned platelet rich plasma (ACP), without performing endolaser photocoagulation and silicone oil tamponade. Material and Methods. The surgery technique involved performing the 25,27-gauge vitrectomy, removing the posterior hyaloid membrane, the inner limiting membrane in the presence of an epiretinal membrane, paracentral retinotomy, removing the choroidal neovascular membrane during retinotomy, pneumoretinopexy, ACP instillation in the retinotomy area in 2-3 layers without endolaser photocoagulation and silicone oil tamponade. Seamless closure of sclero and conjunctivotomy with a layer of autologous conditioned plasma. 17 patients with visual acuity from 0.02 to 0.08 were treated. Results. A full retinal reattachment and closure of the retinotomy opening in the late postoperative period was noted in all patients. Not a single recurrent retinal detachment was recorded. Complete closure of sclero and conjunctivotomy without the use of additional suture fixation in all cases was achieved. Visual acuity after removal of the cicatricial choroidal membrane in the long-term period was 0.03-0.2. Conclusion. Surgical treatment of the cicatricial stage of choroidal neovascular membranes using autologous conditioned plasma to close the retinotomy defect after removal of cicatricial choroidal neovascular membrane without endolaser coagulation of the retina and silicone tamponade, followed by seamless blocking of the sclero and conjunctivotomy with autologous conditioned plasma is a modern technique that allows to achieve high anatomical and functional results, minimizing the risk of postoperative complications.

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EEG indicators of the central nervous system in individuals with different levels of psychophysiological adaptation

Year: 2019, volume 15 Issue: №4 Pages: 965-967
Heading: Brief Reviews Article type: Short message
Authors: Torubarov F.S., Zvereva Z.F., Lukyanova S.N.
Organization: State Research Center— Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The purpose of the study is to assess functional activity of the brain, individual structural and functional formations of the central nervous system at different levels of psychophysiological adaptation (PFA) and to identify their contribution to the formation of low PFA level. Material and Methods. Using psychological and visual-motor tests, methods of heart rate variability, functional state of structural and functional formations of the central nervous system: "cortex", "cortical-subcortical interaction", "central regulation of the cardiovascular system" was evaluated; the integral PFA level was determined using the evaluation results. EEG was used to evaluate brain functional activity and the listed CNS formations. Results. As the level of PFA in the EEG decreased, indicators regarded as the anomalous ones increased: type IV EEG; unstable EEG dynamics; high index of (31 activity; flashes of bilateral synchronous waves. The maximum number of abnormal EEG parameters was revealed at low FS of structural and functional formation "central regulation of the cardiovascular system" in persons with low PFA level. Conclusion. Identification of the maximum number of abnormal EEG indicators at low FS of structural and functional formation of the central nervous system "central regulation of the cardiovascular system" in persons with low PFA level testified to its main contribution to the formation of a low integral level of PFA.

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To live saving lives

Year: 2019, volume 15 Issue: №2 Pages: 392-395
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Lazarenko Ya.S., Nikitina V.V.
Organization: Saratov State Medical University
Summary:

The article provides the data on the activity of the Saratov doctors at the front and in the rear during the Great Patriotic War and their contribution to the development of medicine, devotion of a profession and the sense of responsibility for people»s lives.

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In memory of veterans of the Great Patriotic War who chaired the department of biology of Saratov State Medical University

Year: 2019, volume 15 Issue: №2 Pages: 389-392
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Durnova N.A., Andronova T.A., Gladilin Yu.A.
Organization: Saratov State Medical University
Summary:

The present work highlights the facts about two scientists who in diferent years worked as chairs of the department of general biology at the Saratov Medical Institute and who participated in the Great Patriotic War — professor Alexander Stepanovich Konstantinov, doctor of biological sciences, and associate professor Alexander Evgenievich Sholpo.

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2019_02_389-392.pdf1.51 MB

In memory of veterans of the Great Patriotic War who chaired the department of biology of Saratov State Medical University

Year: 2019, volume 15 Issue: №2 Pages: 389-392
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Durnova N.A., Andronova T.A., Gladilin Yu.A.
Organization: Saratov State Medical University
Summary:

The present work highlights the facts about two scientists who in diferent years worked as chairs of the department of general biology at the Saratov Medical Institute and who participated in the Great Patriotic War — professor Alexander Stepanovich Konstantinov, doctor of biological sciences, and associate professor Alexander Evgenievich Sholpo.

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Activity of the museum of history of Saratov State Medical University name after V. I. Razumovsky as an important factor of educational process and familiarization with cultural heritage

Year: 2019, volume 15 Issue: №2 Pages: 383-389
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Bugaeva I.O., Erugina M.V., Ishchenko Yu.V., Shumilova L.N.
Organization: Saratov State Medical University, Volga Region Cooperative Institute (Branch) of Russian University of Cooperation
Summary:

The diverse aspects of activity of the museum of history of Saratov State Medical University are considered. The value of the museum in educational and scientifc processes is shown. The integrating function of the museum and also the mechanism of impact of its activity on familiarizing of students with cultural heritage, formation of competences and moral and esthetic installations are analyzed. On the basis of practical activities of the museum necessity of its integration with various structural divisions of the university is revealed.

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Contribution of Saratov school of dermatology to the study of rare and chronic dermatoses in the 20-30s of the XX century

Year: 2019, volume 15 Issue: №1 Pages: 136-140
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Yakupov IA, Zavyalov Al, Utz SR, Morrison AV, Mizinov DS, Kryukov YuYu.
Organization: Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology of Moscow City Health Department, Saratov State Medical University
Summary:

The article is devoted to the scientific and practical contribution of the staff of the clinic of skin and venereal diseases of the Saratov Medical Institute in the study of etiology, pathogenesisand development of modern methods of diagnosis and treatment of rare and chronic skin diseases in the first half of the twentieth century.

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The activity of phthisiology service of the Saratov region during the Great Patriotic War and the first post-war years

Year: 2019, volume 15 Issue: №1 Pages: 132-136
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Chulochnikov А.А.
Organization: Saratov State Medical University
Summary:

The article presents a brief overview of the tuberculosis service's activities, of epidemiological situation in the Saratov region during the Great Patriotic war, and of contribution of advanced tuberculosis evacuation hospitals in reducing the number of tuberculosis cases among military personnel and civilian population in the Saratov region.

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2019_1_132-136.pdf1.84 MB

Department of Microbiology of Saratov State Medical University name after V. I. Razumovsky: the origins and the history of development (1918-2018)

Year: 2019, volume 15 Issue: №1 Pages: 127-131
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Mikerov A..N, Raykova S.V., Shvidenko I.G., Khodakova N.G., Soboleva E.F., Shapoval O.G., Allyanova M.S., Kutyrev V.V.
Organization: Saratov State Medical University
Summary:

Department of Microbiology, Virology and Immunology is one of the oldest departments of Saratov State Medical University n.a. V. I. Razumovsky. It has the rich historical experience in the organizing of studies and professional activities of students, which is an integral part in training and education of a modern doctor.

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