Saratov JOURNAL of Medical and Scientific Research

Vagapova D.R.

Bashkir Republic Clinical Hospital n.a. G.G. Kuvatov, Head of Immunological Laboratory, Candidate of Medical Science

Proinflammatory cytokine expression in patients with chronic obstructive pulmonary disease

Year: 2010, volume 6 Issue: №2 Pages: 314-317
Heading: Internal Diseases Article type: Original article
Authors: I.S. Abdurakhmanova, V.I. Nikulicheva, D.R. Vagapova, O.A. Enikeyev
Organization: Bashkir State Medical University of the Russian Health Care, Bashkir Republican Clinical Hospital

The research goal was to investigate cytokine profile (IL-1p, 11_-1ра, IL-4, IL-6, IL-8, TNF-a and INF-у) in patients with chronic obstructive pulmonary disease (OOPD). The data of decreasing of anti-inflammatory IL-4 and increasing of proinflammatory cytokines in patients with OOPD were worked out. Inclusion of domestic immunomodulator of immunovenin in standard therapy of OOPD permitted to decrease concentration of proinflammatory cytokines and to increase the level of anti-inflammatory IL-4

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