Saratov JOURNAL of Medical and Scientific Research

Morozova O.L.

Saratov State Medical University n.a. V.I. Razumovsky, Department of Pathological Physiology, Scientific Research Institute of Fundamental and Clinical Uronephrology, Department of Clinical Pharmacology and Pathological Physiology, Chief Research Assistant, Assistant Professor, Candidate of Medical Science

Modern conceptions about mechanisms of progression process of hip dysplasia in children (review)

Year: 2011, volume 7 Issue: №3 Pages: 704-710
Heading: Traumatology and Orthopedics Article type: Review
Authors: Sertakova А.V., Morozova O.L., Norkin I.A., Anisimov D.I.
Organization: Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

In the literature review of modern data concerning mechanisms of formation and progression process of hip dysplasia in children is represented. The questions concerning classification, processes of morphological and functional (biochemical) change of osteocartilaginous components of hip in children with connective tissue dysplasia, changes of content of remodeling and skeletal system degradation markers, angiogenesis in the process of progression of pathological changes in joint are taken up

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Pathogenic basis and modern prospects in early diagnostics of nephrosclerosis in children with vesicoureteral reflux

Year: 2011, volume 7 Issue: №1 Pages: 151-157
Heading: Urology Article type: Review
Authors: Morozov D.A., Morrison V.V., Morozova O.L., Lakomova D.Y.
Organization: Saratov State Medical University
Summary:

The present article summarizes modern conceptions of tubulointerstitial fibrosis development mechanisms in children with vesicoureteral reflux. The review deals with the questions of extracellular matrix components accumulation and disintegration, tissue hypoxia, remodeling of blood flow, concentration changes in inflammation, sclerosis and angiogenesis biomarkers in the progress of nephrosclerosis

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Causative agents of urinary tracts infection in children with obstructive uropathy

Year: 2010, volume 6 Issue: №2 Pages: 442-446
Heading: Urology Article type: Original article
Authors: P.V.Glybochko, A.A. Svistunov, O.L. Morozova, D.A. Morozov, S.A. Scherbakova, E.S. Kazakova, I.A. Kasjan
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Russian Research Anti-Plague Institute «Microbe», Saratov State Medical University
Summary:

167 children with different variants of congenital obstructions of urinary tracts were examined; the causative agents of urinary tracts infections were analyzed in all the cases. The changes of the cytokines levels were determined in those patients which had the more often found causative agents in the analyses. It was mentioned that of the total patients with obstructive uropathy (OU) the fifth part in the absence of bacteriuria had a pathogen in biopsy material (BM) of urinary tracts. In fourth part of cases microorganisms that were detected in BM and urine did not matched. The changes of cytokines levels in urine did not have any species-specific dependence on causative agent

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Comparative analysis of perioperative period in children with different corrections of vesicoureteral reflux

Year: 2010, volume 6 Issue: №1 Pages: 182-188
Heading: Urology Article type: Original article
Authors: P.V. Glybochko, A.A. Svistunov, O.L. Morozova, D.A. Morozov, B.V. Dolgov, F.K. Napolnikov
Organization: Saratov State Medical University
Summary:

The article presents the analysis of perioperative period of 52 children with different variants of correction of vesicoureteral reflux. It was based on acute-phase proteins amount, cytokines level and adhesion molecules content in blood and urine. the study revealed that if the correction is performed during the latent phase of chronic obstructive pyelonephritis the preference should be given to the endoscopic operations as they do not lead to acute inflammatory process in the urinary tract

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