Saratov JOURNAL of Medical and Scientific Research

differential diagnosis

The peculiarities of morphological differential diagnostics of intradural tumor localized at the level of medullary cone and cauda equina roots

Year: 2018, volume 14 Issue: №3 Pages: 567-570
Heading: Traumatology and Orthopedics Article type: Case report
Authors: Matveeva O.V., Bazhanov S.P., Ponomareva Е.Е., Tolkachev V.S.
Organization: Penza Regional Oncology Centre
Summary:

Aim: to demonstrate the necessity of modern methods of morphological verification in the differential diagnostics of primary and secondary neoplastic lesion of spinal cord. It is shown that histogenesis of tumor cells should be regarded from the viewpoint of comparative assessment of traditional and complementary methods of morphological verification that outlines the necessity of complex differential morphological diagnostics with apparent priority of immunohisto-chemical methods for the verification of final diagnosis of metastatic lesion in a rarely seen localization.

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Biomarkers content in blood serum of patients with osseous neoformations

Year: 2016, volume 12 Issue: №3 Pages: 358-361
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Korshunov G.V., Pavlenko А.А., Puchinyan D.M., Shakhmartova S.G.
Organization:
Summary:

The aim of the study was the estimation of several biomarkers in differentiation diagnostics of tumour diseases in osseous system. Material and methods. 160 patients with benign (115) and malignant (45) osseous neoformations were investigated. Neopterine, tumour necrosis factor (TNF-а), interleukin-6, adhesion molecules of vessel endothe-lium (sVCAM-1) and vascular endothelial growth factor (VEGF) levels were identified by ELISA solid-phase test and compared with the levels of 20 apparently healthy individuals. Tumor verification was fulfilled by X-ray, CT, MRI and histomorphological essay. Results. Both benign and malignant osseous tumour patients showed increased levels of neopterine, TNF-а and interleukin-6 being more significant with malignant processes. The level of sVCAM was decreased in patients of both groups and VEGF level corresponded to the control, these indexes did not show any differences between the groups. The assessment of diagnostic value of these cytokines indicates that positive results for TNF and neopterine give the ground for the final diagnostic decision while the same results for interleukin-6 give moderate basement for diagnostic decision. Conclusion. Increased TNF-а and neopterine levels allow substantiating the difference between benign and malignant osseous tumours and improving diagnostic quality.

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Bloch — Sulzberger syndrome

Year: 2015, volume 11 Issue: №3 Pages: 457-462
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Utz S.R., Grashkina I.G., Eremina M.G., Akimova I.S.
Organization: Saratov State Medical University
Summary:

Five clinical observations in pediatric patients with Bloch — Sulzberger syndrome are presented. The observation had been performed for six months. The differential diagnosis depending on the stage of the disease was done. The article contains variants of treating patients of this category.

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Difficult diagnosis in a dermatologist's practice (description of a clinical case of late cutaneous porphyria)

Year: 2015, volume 11 Issue: №3 Pages: 450-453
Heading: Dermatovenerology Article type: Case report
Authors: Utz S.R., Bakulev A.L., Slesarenko N.A., Eremina M.G., Muratova D.S.
Organization: Saratov State Medical University
Summary:

The article presents a case report of clinical observations of late cutaneous porphyria in a 50-years old patient. The data of the etiology, pathogenesis and clinical picture are summarized. A differential diagnosis with vulgar disease, acquired epidermolysis bullosa and pseudoporphyria. The results of a successful comprehensive treatment of disease by drugs quinoline series, systemic glucocorticosteroids, phlebotomy.

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2015_03-01_450-453.pdf1.13 MB

Infant acropustulosis

Year: 2015, volume 11 Issue: №3 Pages: 445-447
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Utz S.R., Eremina М.G., Akimova I.S.
Organization: Saratov State Medical University
Summary:

A rare clinical case of an infant acropustulosis at a newborn child is presented in the article clinical signs, histology treatment are described.

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Identification of acute lower respiratory tract infections by transresonant functional topography in medical military post

Year: 2011, volume 7 Issue: №1 Pages: 073-076
Heading: Internal Diseases Article type: Original article
Authors: Lebedeva M.N., Streltsova E.V., Terehov I.V., Khatskevich V.L.
Organization: Saratov Military Medical Institute, Medical Unit 21222
Summary:

Community-acquired pneumonia (CAP) is usually characterized by absence of clinical signs. Rapid diagnostic tests with high sensitivity for lower respiratory tract infections (LRTI) could lead to improved patient care. 97 servicemen with LRTI were analyzed to compare radiological, clinical and transresonant functional topography (TRFT) findings in the differential diagnosis of CAP The research data revealed that TRFT findings improve the assessment of pneumonia based on carefully taken case history and physical examination. TRFT data contributed to development of treatment course algorithm in case of acute respiratory tract infection

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Systemic Lupus Erythromatosis or Hiv Infection «Mask»?

Year: 2009, volume 5 Issue: №3 Pages: 444-446
Heading: Practice physician Article type: Short message
Authors: Е.Н. Скрябина, Н.А. Магдеева, И.Ф. Нам
Organization: Saratov State Medical University, Saratov Regional Clinical Hospital
Summary:

The difficulties while conducting the differential diagnosis between systemic lupus erythromatosis (SLE) and HIV infection due to their clinical resemblance are reflected in this article

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