Saratov JOURNAL of Medical and Scientific Research

atrial fibrillation

Clinical and echocardiographic features of heart failure in patients with obstructive sleep apnea and atrial fibrillation

Year: 2016, volume 12 Issue: №3 Pages: 349-353
Heading: Cardiology Article type:
Authors: Cherkasova S.A., Shvarts Yu.G.
Organization: Saratov State Medical University
Summary:

The combination of heart failure, obstructive sleep apnea syndrome and atrial fibrillation is a widespread case. Besides, the correlation between these pathologies has not been accurately determined yet. The aim of the research is to determine the specific features of heart failure in patients with atrial fibrillation. Material and Methods. 174 patients were involved in the research. There were people at the age of 75 and younger suffering with heart failure. 116 of them also experienced artrial fibrillation and 58 sinus rhythm. In addition, all the patients involved had hypertension. The patients underwent echocardiography and respiratory monitoring. Results. Statistical analysis showed that atrial fibrillation was a more powerful predictor of the occurrence of obstructive sleep apnea than heart failure. Furthermore, we have found significant peculiarities in relations between the features of heart failure, presence and severity of obstructive sleep apnea in the group of the patients with atrial fibrillation. Remodeling of the left heart cameras was more typical for the patients with atrial fibrillation. Conclusion. Heart failure has significant features in patients with atrial fibrillation and obstructive sleep apnea.

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Atrial fibrillation and obstructive sleep apnea syndrome

Year: 2016, volume 12 Issue: №2 Pages: 157-161
Heading: cardiac surgery Article type: Review
Authors: Cherkasova S.A.
Organization: Saratov State Medical University
Summary:

The literature review on the connection between atrial fibrillation and obstructive sleep apnea syndrome has been made. The etiology of sleep apnea, the mechanism of night breath pauses and possible consequences of this disorder have been described. The statistical data related to the frequency of atrial fibrillation among sleep apnea patients were presented in this article. The evidence regarding possible mechanisms of pathogenetic relation between atrial fibrillation onset and sleep breathing disorders was described. Nowadays it is assumed that night desaturations, the increase of sympathetic tonus, obesity, cardiac pathology, the increase of general inflammatory markers connected with sleep breathing disorders are the factors which contribute to the arrhythmia in patients with apnea. In the review the modern data concerning influence of apnea on the course of atrial fibrillation and recurrence of the arrhythmia relapse after cardioversion have been presented. The positive impact of sleep apnea treatment on the progress of atrial fibrillation was noted as well. The literature analysis has shown that pathogenetic mechanisms characterizing the connection between atrial fibrillation and sleep apnea have not been completely defined. The amount of published studies relating to the influence of apnea on the progress and long-term results of atrial fibrillation treatment is insufficient. There are not enough data about the frequency of different forms of atrial fibrillation in patients with apnea. There are other issues which require further investigations.

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Features of pharmacotherapy and clinical course of atrial fibrillation in patients with type 2 diabetes in real clinical practice. Saratov Journal of Medical Scientific

Year: 2014, volume 10 Issue: №1 Pages: 178-185
Heading: Parmacology Article type: Original article
Authors: Graifer l.V., Reshetko O.V., Furman N.V., Dolotovskaya P.V.
Organization: Saratov Institute of Cardiology, Russia, Saratov State Medical University
Summary:

The aim of the study was to investigate the clinical status of patients with atrial fibrillation (AF) and diabetes mellitus (DM) type 2 and to identify differences in the treatment of AF, conducted in the cardiology departments of multidisci-plinary teaching hospitals of the Saratov city. Materials and methods. A comparative retrospective analysis of 1041 pharmacoepidemiological solid history of patients with AF who were hospitalized in emergency, and in the planning department of cardiology of 2 multidisciplinary teaching hospitals of the Saratov city consecutively in a calendar year on the AF, recorded on an electrocardiogram. Results. Among all patients with AF, patients with DM accounted for 20.2%. Among them were women, they were younger, they developed fibrillation at a younger age, they differed more severe structural heart disease, among which was significantly greater with myocardial infarction, nearly all had symptoms of heart failure. Patients with DM performed less frequently cardioversion, and to monitor heart rate often preferred a combination of beta-blockers and digoxin. 100% of patients with DM had a higher risk of thromboembolic complications (91.9% without diabetes) in both groups, oral anticoagulants (OAC) prescribed often enough. Conclusion. DM was diagnosed in every fifth patient with AF, especially among women and patients with persistent AF and is associated with the presence of more severe organic heart disease compared with patients without DM. All patients on the background DM was a high risk of thromboembolic complications, i.e. OAC must be assigned in 100% of cases, but in the surveyed hospitals OAC were appointed only in 23% of cases.

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Early thyroid gland dysfunction and biorhythmic activity disturbance in patients with cardiovascular pathology and atrial fibrillation

Year: 2012, volume 8 Issue: №4 Pages: 926-933
Heading: Internal Diseases Article type: Review
Authors: Baurina Yu.O., Mayskova Е.А., Shvarts Yu.G.
Organization: Saratov State Medical University
Summary:

The review deals with the problem of combined pathology of the thyroid gland and cardiovascular system, the state of thyroid homeostasis in atrial fibrillation. The main mechanisms of action of thyroid hormones on the heart and blood vessels, particularly changes in the cardiovascular system with hypo-or hyperthyroidism; the possibility of substitution therapy in subclinical disease have been presented in the article. Characteristics of daily rhythmic activity of thyroid gland in normal and various pathological conditions with persistent and paroxysmal atrial fibrillation have been considered.

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Control of anticoagulant therapy and quality of life of patients with atrial fibrillation (review)

Year: 2012, volume 8 Issue: №2 Pages: 258-265
Heading: Internal Diseases Article type: Review
Authors: Artanova E.L., Shvarts Y.G.
Organization: Saratov State Medical University
Summary:

The review presents the published data on the relevance of the problem of thromboembolic complications in atrial fibrillation, the peculiarities of anticoagulant therapy for this disease. The relationship of clinical characteristics of patients with anticoagulant dose adjustment algorithms has been described. The problem of ethical issues of out of clinical trials patients and the dynamics of their quality of life against the background of long-term use of anticoagulant have been considered.

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PECULIARITIES OF CARDIAC SEPTUM MOVEMENT IN ATRIOVENTRICULAR JUNCTION AREA IN PATIENTS WITH PERSISTING ATRIAL FIBRILLATION

Year: 2007, volume 3 Issue: №4 Pages: 79-82
Heading: Internal Diseases Article type: Original article
Authors: N.S. Akimova, L.I. Kuznetsova, E.V. Parhonyuk. Yu.G. Shvartz
Organization: Saratov State Medical University
Summary:

The aim is to stuty specific features of myocardium movement in atrioventricular junction area in patients with associated persistent atrial fibrillation using the Doppler Tissue Imaging (DTI)-mode echocardiography. To our understanding, the results obtained validate fiber changes in atrioventricular junction area at the time of atrial fibrillation, revealed during morphologic studies, and prove DTI diagnostic technique efficiency.