Saratov JOURNAL of Medical and Scientific Research

Norkin I.A.

Saratov State Medical University n.a. V I. Razumovsky, Director of Scientific and Research Institute of Traumatology, Orthopedics and Neurosurgery, Head of Department of Traumatology and Orthopedics, Professor, Doctor of Medical Science

Morphometric justification of algorithm of the choice of method of surgical treatment of dysplastic coxarthrosis

Year: 2015, volume 11 Issue: №2 Pages: 182-186
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Norkin I.A., Anisimova Е.А., Voskresensky O.Yu., Yusupov K.S., Anisimov D.l., Letov A.S., Popryga D.V., Popov A.N.
Organization: Saratov State Medical University
Summary:

Purpose: to define regularities of variability of bone structures of a hip joint depending on type of dysplastic coxarthrosis and to develop tactics of total endoprosthesis replacement. Objects of research. 106 patients with dysplastic coxarthrosis of varying severity, passing treatment on the basis of Federal State Budget Institution of Saratov Scientific Research Institute of Traumatology and Orthopedics from 2005 to 2014 applying methods X, KT-, MRT-metry variation and statistical methods. Results: According to anatomic features of a hip joint at dysplastic coxarthrosis of various types algorithms of choice of acetabularand femoral components of endoprosthesis, and also tactics of total endoprosthesis replacement in groups of research are developed. Conclusion. The choice of a standard size of an endoprosthesis of a hip joint needs to be carried out taking into account X-ray anatomic features of a hip joint and degree of expressiveness of the dysplastic changes. At dysplastic coxarthrosis of the l-ll types it is necessary to carry out standard total endoprosthesis replacement; at coxarthrosis of the III type —total endoprosthesis replacement in combination with plasticity of a roof of acetabular hollow; at coxarthrosis of the IV type — total endoprosthesis replacement in a combination from the shortening femur osteotomy.

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Nerve tissue growth factors as markers of evaluation of neuro-genesis processes in traumatic spinal cord disease

Year: 2014, volume 10 Issue: №3 Pages: 446-449
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Uljanov V.Yu., Norkin I.A., Drozdova G.A., Konjuchenko E.A.
Organization:
Summary:

Objective: immunological differentiation effects regeneration of nerve tissue in the acute and early periods of traumatic spinal cord disease on the basis of assessment of the dynamics of content neurospecific proteins in serum affected. Material and Methods. Content of neurospecific proteins in the blood serum has been studied by enzyme immunoassay in 40 patients with spinal cord injuries. Results. Dynamics and quantitative changes in the content of chronometric neurospecific proteins in serum of patients in acute and early periods of traumatic spinal cord disease is characterized by two-phase increase in the concentration CNTF; monotonic increase in the content of NT-3 in all periods of observation; biphasic increase in the levels of NT-4 to 1-4th and 14-th day from the date of injury. Conclusion. Complex research of neurospecific levels of proteins in the serum allows one to evaluate selectively the individual components of the process of regeneration of nerve tissue in acute and early periods of traumatic spinal cord disease.

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Correction of immune disorders in patients with malignant tumors at level of craniovertebral junction and upper cervical spine

Year: 2013, volume 9 Issue: №2 Pages: 295-301
Heading: Oncology Article type: Original article
Authors: Bazhanov S.P., Uljanov V.Yu., Norkin I.A., Gulyaev D.A.
Organization: Russian Scientific Research Institute of Neurosurgery n.a. Professor A. L. Polenov
Summary:

Objective: To study the cellular and humoral immunity in patients with malignant tumors of the upper cervical spine. Material and methods: The study included 22 patients with malignant tumors of the craniovertebral junction and upper cervical spine. To assess the function of the immune system the methods of population and subpopulation immuno-phenotyping of peripheral blood lymphocytes have been applied. Cytokine parameters and functional status (cytotoxic) activity of NK-cells have been studied using immunofermental methods. The indices have been presented in absolute and relative terms. All the patients have been subjected to the adjuvant therapy. Results: Correction of cellular immunity has led to significant increase in CD3 + (T-lymphocytes) and CD3 + CD8 + (T-killers). Cytokine levels in the groups studied in the dynamics have not been significantly altered. The changes of cytotoxic (functional) activity of NK-cells in the first group after the combined treatment have been considered to be higher than before the treatment. Cytotoxic index of (functional) activity of NK-cells in the second group under the study after the combined treatment has been determined to be lower than before the treatment. Conclusion: It has been found out that the application of complex treatment accompanied by immunotropic therapy may positively influence the immune status.

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Modern techniques in treatment of chest and extremity polytraumas

Year: 2012, volume 8 Issue: №4 Pages: 982-988
Heading: Traumatology and Orthopedics Article type: Review
Authors: Khmara A.D., Norkin I.A., Khmara Т.G.
Organization: Saratov State Medical University
Summary:

The article presents a review of Russian and foreign literature on polytrauma. It touches upon the following points: statistic data of the pathology occurrence, mortality and disability from injuries, classification and methods of diagnostics and treatment of multiple traumas and polytraumas.

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Organization and development of surgical rehabilitation of patients with traumas and their effects

Year: 2012, volume 8 Issue: №2 Pages: 313-317
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Norkin I.A., Chernyshov V.V., Barabash А.P.
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

Objective: To improve the efficiency of surgical rehabilitation of patients with traumas, their effects. Materials and methods: Short-term and follow-up results of the surgical treatment of patients with traumas and their effects have been analyzed. Statistical research methods have been used. Results: the efficiency of medical technologies during the early rehabilitation of patients has been demonstrated. Conclusion: Adoption of the most efficient medical technologies of general surgical treatment and postoperative rehabilitation of patients with traumas and their effects in daily practice provides high-grade restoration of the extremity's function, shortening of treatment period, decrease in number of complications and invalidism

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Topographic and anatomic features of transverse foramen of cervical vertebra in age and sex aspect

Year: 2012, volume 8 Issue: №2 Pages: 177-181
Heading: Macro- and Micromorphology Article type: Original article
Authors: Anisimov D.I., Norkin I.A., Nikolenko V.N., Anisimova E.A., Aleshkina О.Yu., Ostrovsky V.V.
Organization: Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

Purpose: to reveal regularities of variability of morphometric parameters of foramen of transverse process of cervical vertebra. Materials and Methods. Method of osteometry was used to determine size of transverse process of cervical vertebra at 112 adult skeletons. Results. Sexual dimorphism of size of transverse process of cervical vertebra, topographic variability of size, form and foramen orientations were revealed. Conclusion. Foramen size prevail at men over women by 0,5-1,5 mm and has characteristic of fluctuating dissymmetry

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Modern conceptions about mechanisms of progression process of hip dysplasia in children (review)

Year: 2011, volume 7 Issue: №3 Pages: 704-710
Heading: Traumatology and Orthopedics Article type: Review
Authors: Sertakova А.V., Morozova O.L., Norkin I.A., Anisimov D.I.
Organization: Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

In the literature review of modern data concerning mechanisms of formation and progression process of hip dysplasia in children is represented. The questions concerning classification, processes of morphological and functional (biochemical) change of osteocartilaginous components of hip in children with connective tissue dysplasia, changes of content of remodeling and skeletal system degradation markers, angiogenesis in the process of progression of pathological changes in joint are taken up

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Cytological evaluation and prediction of progression of acute erosive ulcered lesions of upper parts of gastrointestinal tract in acute and early periods of cerebrospinal trauma

Year: 2010, volume 6 Issue: №3 Pages: 701-703
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Norkin I.A., Ulyanov V.Yu., Konyuchenko E.A.
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

80 cytological preparations derived by fibrogastroduodenoscopy from 20 patients with cerebrospinal trauma at cervical part level served as the research subject. Dynamics of the progression of acute erosive ulcered lesions of mucous membrane of the upper parts of the gastrointestinal tract was studied on the basis of the cytological analyses of mucous membrane biopsy materials. In the course of our work we used endoscopic (fibrogastroduodenoscopy) and cytological research methods. Cytological analyses of mucous membrane biopsy materials were carried out on the 7th, 14th, 21st and 28th day. Biopsy material cellular composition was evaluated on the grounds of the calculation of neutrophilic leukocytes and epithelial cells with the use of an immersion objective. In so doing we registered neutrophilic leukocyte number for 100 cells and determined neutrophilic and epithelial index. Monitoring of neutrophilic leukocyte number enables to determine presence or absence of inflammatory changes in stomach mucous membrane and duodenum in different periods of cerebrospinal trauma

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Spinal Hemangiomas

Year: 2010, volume 6 Issue: №2 Pages: 428-432
Heading: Traumatology and Orthopedics Article type: Review
Authors: I.A. Norkin, S.V. Likhachev, A.Yu. Chomartov, A.I. Norkin, D.M. Puchinian
Organization: Saratov Scientific Research Institute of Traumatology and Orthopedics
Summary:

The given article considers the modern view on etiology, pathogenesis, classifications, clinical picture, diagnosis and treatment of spinal hemangiomas. Advantages of vertebroplasty over the other techniques of treatment of studied pathology are presented

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Using of computer simulation in surgical treatment of patients with fractures of proximal femur

Year: 2010, volume 6 Issue: №2 Pages: 419-421
Heading: Traumatology and Orthopedics Article type: Original article
Authors: I.A. Norkin, A.A. Svistunov, D.A. Markov, O.A. Kautz, S.P. Shpinyak A.G. Khachatryan, V.N. Belonogov
Organization: Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

In this article questions of femur computer models base making for future it using in free patients medicine are discussed. Last allows possibility for educate doctors using computer models, increase their professional level and makes complications decrease. Comparing of fixation properties of DHS and PFN-A was performed

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