Saratov JOURNAL of Medical and Scientific Research

Chuprov A.D.

S. Fedorov Eye Microsurgery Federal State Institution, Orenburg branch, Director, Professor, DSc

The effectiveness of subtotal vitrectomy with retinotomy in surgical treatment of severe forms of proliferative diabetic retinopathy with retinal detachment

Year: 2020, volume 16 Issue: №1 Pages: 315-317
Heading: Ophtalmology Article type: Original article
Authors: Chuprov A.D., Gorbunov A.A., Kazennov A.N., Kuvaitseva Yu.S.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

The purpose of the study is to increase the efficacy of surgical treatment of severe stages of proliferative diabetic retinopathy in combination with circular retinotomy. Material and Methods. The operations performed in 2016-2018 on patients with proliferative diabetic retinopathy in combination with traction retinal detachment (17 eyes). The patients' age ranged from 24 to 69 years. Tractional retinal detachment was diagnosed alongside with PDR3-4 in all eyes. In 10 (58.8%) previously operated eyes we diagnosed the relapse of retinal detachment. In 14 eyes (82.3%), vitrectomy was performed in combination with phacoemulsification, 3 eyes (17.6%) were already pseudophakic. Results. We obtained complete anatomical attachment of the retina in all 17 cases (100%). All patients we kept on 5700 cSt silicone tampon-ade. Circular retinotomy was performed on 10 (58.8%) eyes with a relapse. The period of keeping silicone oil 5700 cSt in the vitreous cavity after a circular retinotomy varied (from 1 to 3 years), emulsification of silicone oil occurred in none of the cases. Secondary glaucoma developed in 3 eyes. Conclusion. Circular retinotomy in combination with prolonged tamponade of the vitreous cavity with silicone oil provides stable anatomical effect.

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Application of multivariate statistical analysis for evaluation of management of ophthalmological care to the population of the Orenburg region

Year: 2019, volume 15 Issue: №2 Pages: 568-572
Heading: Ophtalmology Article type: Original article
Authors: Chuprov A.D., Lositsky A.O., Trubnikov V.A.
Organization: Orenburg branch of S. Fedorov Eye Microsurgery Federal State Institution
Summary:

The purpose of this study was to identify and study clusters (groups) of medical organizations of the Orenburg region with similar parameters, refecting the level of organization of ophthalmic care to the population. Material and Methods. The proposed method of evaluation is based on the use of the method of multivariate statistical analysis of the structure and activity of ophthalmological units of primary health care of the Russian Federation, with the allocation of groups of structures under research with similar evaluation characteristics and graphic representation of the results. Evaluation criteria are: availability of specialized ophthalmological care for the population, stafng level, overall and primary disease incidence, incidence on separate nosological groups, general and primary disability indicators. Results. Based on the data representative of the organization of ophthalmic care 50 medical organizations of the Orenburg region, providing primary health care were divided into 3 clusters. Indicators of the ophthalmic care management for each of the clusters were characterized. Conclusion. The results of the study allow us to identify groups of medical organizations that require diferent approaches in management decision-making in order to improve the ophthalmological service of an individual subject of the Russian Federation.

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Corneal endothelial cells condition after thermokeratocoagulation in a long-term period.

Year: 2019, volume 15 Issue: №2 Pages: 566-568
Heading: Ophtalmology Article type: Original article
Authors: Chuprov A.D., Kuznetsov I.V., Pasikova N.V., Kuznetsova V.I.
Organization: Orenburg branch of S. Fedorov Eye Microsurgery Federal State Institution
Summary:

The purpose of the research was to assess the quantitative and qualitative state of the corneal endothelium after thermokeratocoagulation in a long-term period. Material and Methods. The main group consisted of 18 patients (36 eyes) after thermokeratocoagulation, which was performed from 19 to 28 years ago. The control group consisted of 22 patients (44 eyes) aged from 45 to 58 years (middle age 51.3±3.2 years) from refraction and axial hypermetropy various degree without the previous surgical interventions. The research was performed on a non-contact mirror scanning microscope EM-3000 (Tomey, Japan). Results. The endothelial cells density in the main group averaged 2245.4±316.2 cells / mm2, in the control group 2661.7±169.2 cells / mm2 (p<0.05). The coefcient of endothelial cell size variability counted 0.34, in the control group 0.26 (p<0.05). The percentage of hexagonal corneal endothelial cells in patients after thermokeratocoagulation averaged 53.7±14.9 % in patients of the control group 74.3±6.5 % (p<0.05). Conclusion. In the long-term period patients showed a statistically signifcant decrease in the corneal endothelial cells density, a decrease in the percentage of hexagonality and an increase in the coefcient of cell size variability.

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Eyesight condition in frst-year pupils

Year: 2019, volume 15 Issue: №2 Pages: 563-565
Heading: Ophtalmology Article type: Original article
Authors: Chuprov A.D., Voronina A.E.
Organization: Orenburg branch of S. Fedorov Eye Microsurgery Federal State Institution
Summary:

Purpose: to determine the characteristics of eyesight in frst-year pupils. Material and Methods. Parents were initially interviewed to establish the presence and severity of symptoms of dry eye syndrome in their children. The second stage involved ophthalmologic examination which included non-contact autorefractometry on Plusoptix A09 device and checking visual acuity with and without correction. Results. Autorefractometry revealed emmetropia in the majority of cases (79.16 %), myopia was identifed in 3.34 %, accommodation disturbance — in 11.25 %, hypermetropia — in 3.75 %, astigmatism — in 2.5 %. Visual acuity test in the majority of children revealed the maximum acuity, while visual acuity of less than 0.5 was detected in 5.4 % of frst-year pupils. A survey for symptoms of dry eye syndrome showed minimal manifestations in frst-year pupils from 0 points for the majority, up to 8 points. The most frequent complaint among the respondents was hypersensitivity to light (33.75 %) and frequent eye infammation (23.3 %). Watching TV was the most frequently reported visual workload. Conclusion. The majority of frst-year pupils (78.3 %) had high visual acuity of 1.0; 3.34 % of the children had myopia; 11.25 % had accommodation disturbance.

Role of melatonin in pathogenesis of age-related macular degeneration

Year: 2019, volume 15 Issue: №2 Pages: 559-563
Heading: Ophtalmology Article type: Review
Authors: Khodzhaev N.S., Chuprov A.D., Kim S.M.
Organization: The S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people aged 50 years and older in the advanced world. The article deals with the epidemiology and pathogenesis of the disease. Special attention is given to a new approach to the prevention and treatment of AMD with the help of melatonin; modern management options and scientifc achievements are discussed. Many researchers have shown that melatonin is able to protect retinal epithelial cells from oxidative damage. Perhaps the physiological reduction of melatonin in the elderly may be an important factor in the dysfunction of the retinal pigment epithelium, which is the cause of AMD.

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