Saratov JOURNAL of Medical and Scientific Research

preperimetric glaucoma

Comparative analysis of morphometric parameters of the optic disc in glau-comatous eyes with discs of average and large size

Year: 2019, volume 15 Issue: №2 Pages: 510-514
Heading: Ophtalmology Article type: Original article
Authors: L'vov V.A., Machekhin V.A., Fabrikantov O.L.
Organization: S. Fedorov Eye Microsurgery Federal State Institution, Tambov State University, Medical Institute

Purpose: using HRT and OCT to compare the outcomes of the examination of optic disc parameters in normal eyes and glaucomatous eyes with discs of standard (average) and large size. Material and Methods. 306 eyes of 160 patients (71 male, 89 female) aged 61.1±10.0 years old were analyzed retrospectively. All eyes were divided into 2 groups: group I included 162 eyes with the disc area of 1.63–2.43 mm2; group II — 144 eyes with the disc area of 2.44– 3.5 mm2. Both groups were divided into fve subgroups (healthy eyes, eyes with preperimetric glaucoma and with different stages of glaucoma). Disc parameters were analyzed using HRT 3 and RTVue-100 simultaneously in the same eyes. Results. In the group of eyes with average discs both methods (HRT and OCT) revealed the same examination outcomes of all disc parameters indicating high statistical signifcance of the diference between groups of healthy eyes and eyes with preperimetric glaucoma. In the group with large discs the parameters of peripapillar retina (RNFL) play a signifcant role. Conclusion. Preperimetric glaucoma is a valuable indicator to detect early glaucoma in the group of eyes with average discs. However, in large discs according to either HRT or OCT data peripapillar retinal parameters are the most sensitive, whereas the alterations of the internal structure of the disc itself appear later.

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