Saratov JOURNAL of Medical and Scientific Research

Bolotova N.V.

Saratov State Medical University, Head of Department of Children Diseases Propaedeutics, Children Endocrinology and Diabetology, Doctor of Medical Science, Professor

Neuroendocrine mechanisms of regulation of eating behavior (review)

Year: 2020, volume 16 Issue: №3 Pages: 707-713
Heading: Endocrinology Article type: Review
Authors: Bolotova N.V., Kurdiyan M.S., Filina N.Yu.
Organization: Saratov State Medical University
Summary:

The review analyzes the published data on the role of various neurotransmitters, hormones involved in the formation and disturbance of eating behavior. To search for articles, the PubMed database was used, as well as the archives of the journals "Pediatrician", "Medicine: theory and practice" Environment and Energy Science", "Problems of Endocrinology", "Modern Technologies in Medicine", "Russian Journal of Cardiology", "Universum: Medicine and Pharmacology", "Questions of Children's Dietetics", Kursk Scientific and Practical Bulletin "Man and His Health". The literature review used 49 literature sources; articles were published in the period from 2004 to 2020.

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Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development

Year: 2010, volume 6 Issue: №1 Pages: 178-182
Heading: Urology Article type: Original article
Authors: N.V. Bolotova, D.A. Morozov, N.U. Raygorodskaya, D.A. Zharkov, M.M. Grigorjeva, E.N. Tsmokalyuk
Organization: Saratov State Medical University
Summary:

The number of patients with disorders of sexual development (DSD) has increased in 3.54 times during the last three years. The aim is to define the structure of intersexual disorders in children from Saratov, criteria of gender assignment and surgical approach. During the period of three years (from 2006 till 2008) 58 children with DSD aged 0 - 17 were examined. Assessment of external genitals, cytogenetic investigation, hormonal tests were performed. Imaging studies included ultrasonography, cystourethroscopy and laparoscopy with histological investigation. Considering the data DSD in children from Saratov compose sex chromosome DSD - 21,4 %, Gonadal dysgenesis - 26,2%, ovotesticular DSD - 2,3%, 46,ХХ testicular DSD - 2,3 %, complete androgen insensitivity syndrome - 4,7%. The criteria of gender assignment and surgical approach have been described in the article. The research concludes that the infants with intersexual genitels should be examined in special care centers by multispecialty team. It is nessesary to perform the karyotype test and ultrasonic study in newborns to detect the genetic and gonadal gender of the child

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NEW APPOROACHES TO THE TREATMENT OF OBESITY IN CHILDREN

Year: 2006, volume 2 Issue: №2 Pages: 7-13
Heading: Pediatrics Article type: Original article
Authors: N.V. Bolotova, A.P. Averianov, J.A. Zotova, N.J. Raigorovskaya, S.V. Lazebnicova
Organization: Saratov State Medical University
Summary:

Rehabilitation program for children with complicated obesity was present, including motivating training course, physiotherapy, metformin in children with insulinresistance. We compared effect of complex treatment including magnetic field transcaranialy application with placebo of physiotherapy and with traditional treatment in children at the age 10-15 with complicated obesity, hypothalamic syndrome. We proved the effect of complex treatment with magnetic therapy for decrease of body mass index, blood pressure, improvement lipid spectrum.

Keywords: obesity

THE PECULIARITIES OF AUTONOMOUS NERVOUS SYSTEM DISORDER IN CHILDREN WITH DIABETES MELLITUS TYPE I AND APPROACHES FOR ITS CORRECTION

Year: 2006, volume 2 Issue: №1 Pages: 14-18
Heading: Neurology Article type: Original article
Authors: N.V. Bolotova, A.P. Averyanov, V.Y. Manukyan
Organization: Saratov State Medical University
Summary:

The state of autonomous nervous system in children with diabetes mellitus type I was studied. Autonomous dysfunction was found in 86% of patients, regardless the duration and severeness of the disease. Cardiac autonomic neuropathy was revealed in 41% children. All of them had the deterioration of general condition, activity and mood. Usage of transcranial magnitotherapy has resulted in normalization of autonomous nervous system tone, reactivity, activity of subcortical nervous centers, increase of the number of children with stable regulation. Besides, there was the improvement of cardiac autonomic neuropathy indices, and normalization of psychological status of patients.

EFFICIENCY OF USADE OF MAGNETOTHERAPY IN TREATMENT DIABETIC POLYNEUROPATHY IN CHILDREN

Year: 2007, volume 3 Issue: №1 Pages: 88-91
Heading: Pediatrics Article type: Original article
Authors: N.V.Bolotova, S.V.Hudoshina, U. M. Raygorodskiy
Organization: Saratov State Medical University
Summary:

The clinical data on application of magnetotherapy in treatment of diabetic peripheral polyneuropathy in 75 children (40 girls, 35 boys) of 7 - 10,5 y.o. with diabetes mellitus I type. 30 patients got the correction ofglycemia level. 30 children received with correction of a carbohydrate exchange of therapy running pulse magnetic field in a pulse mode with an induction of a field 45mTI and frequency of 10-16 Hz, appointed to area of shins. The rest 15 children received effect placebo. The usage of magnetic field of the specified parameters, with direction of field along a neurovascular bunch, allowed to increase conductivity of peripheral nerves in 1,5-2 fold with compared start values during one course of magnetotherapy

Keywords: pediatrics

CORRECTION OF MICROCIRCULATORY ABNORMALITIES IN CHILDREN WITH DIABETES MELLITUS TYPE 1

Year: 2008, volume 4 Issue: №2 Pages: 100-104
Heading: Pediatrics Article type: Original article
Authors: N.V. Nikolaeva, N.V. Bolotova, V.F. Lukyanov, E.N. Tkacheva
Organization: Saratov State Medical University
Summary:

Article is devoted to investigation of microcilculatory abnormalities in children with diabetes mellitus type 1 and correction with the help of magnetotherapy.

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