Saratov JOURNAL of Medical and Scientific Research

Postgraduate Institute for Public Health Workers

The vascular- platelet and coagulation hemostasis in preeclampsia and gestational arterial hypertension in the third trimester of pregnancy

Year: 2019, volume 15 Issue: №2 Pages: 501-506
Heading: Ophtalmology Article type: Original article
Authors: Kolenko O.V., Chizhova G.V., Sorokin E.L., Fil A.A., Khodzhaev N.S., Pomytkina N.V.
Organization: Postgraduate Institute for Public Health Workers, The Khabarovsk branch of the S. Fedorov Eye Microsurgery Federal State Institution
Summary:

Purpose: to conduct a retrospective analysis of the initial state of the indicators of systemic hemostasis in women during a complicated pregnancy, to determine its likely relationship with the formation of vascular retinal pathology in the long-term period after childbirth. Material and Methods. The 1st main group consisted of 47 women whose pregnancy proceeded against the background of gestational hypertension. The 2nd main group is represented by 48 women, whose pregnancy was complicated by pre-eclampsia. The control group was formed by 50 women with normal ongoing pregnancy. In women of all groups, the initial state of hemostasis was assessed in the third trimester of pregnancy, according to medical records. Results. It turned out that in women with hypertensive disorders in the third

AttachmentSize
2019_02-1_501-506.pdf311.78 KB

Clinical and etiological and hemostasiological features of isolated optic disk vasculitis

Year: 2019, volume 15 Issue: №2 Pages: 465-469
Heading: Ophtalmology Article type: Original article
Authors: Emanova L.P., Egorov V.V., Smoliakova G.P., Danilova L.P., Povalyaeva D.A., Zhajvoronok N.S.
Organization: Postgraduate Institute for Public Health Workers, The Khabarovsk branch of the S. Fedorov Eye Microsurgery Federal State Institution
Summary:

 Purpose: the study clinical, etiological and intravascular hemostasiological features of isolated optic disk vasculitis (IODV). Material and Methods. 27 patients with IODV. Duration of the disease at the time of initial appeal ranged from 5–7 days to 12 weeks. The criterion for inclusion in the study was the absence in patients systemic vasculitis, severe cardio and cerebrovascular diseases and systemic immunopathological diseases. One of the main places in the study was devoted to laboratory diagnosticmethods — enzyme-linked immunosorbent assay using set of reagents (test system «Bioservice», Russia) for detection of specifc antibodies to various infections in blood serum. The average period of study patients was 12 months. Results. The exudative type of infammation (67 %), moderate hemorrhagic activity and high risk of macular lesions are typical for IODV; in etiological structure of IODV prevail herpes viral infection and foci of chronic bacterial infections. High average infectious index (2.0±0.1) indicates predominance of mixed infections in patients. The results of laboratory studies have established that pathogenetic mechanisms of development of IODV are associated with activation of the vascular-platelet and coagulation hemostasis and depression of fbrinolysis. Conclusion. Close relationship established between changes in intravascular hemostasis and the clinical activity of disease, which necessitates inclusion in program of complex treatment patients with IODV, along with basic corticosteroid therapy and sanitation of infection foci, medications that normalize hemostasis.

AttachmentSize
2019_02-1_465-469_1.pdf297.13 KB

New approach to amnioplasty in surgical treatment of primary progressing pterygium

Year: 2019, volume 15 Issue: №2 Pages: 428-433
Heading: Ophtalmology Article type: Original article
Authors: Bochkareva A.N., Egorov V.V., Smoliakova G.P., Banshchikov P.A., Belous A.V.
Organization: Postgraduate Institute for Public Health Workers, Regional Clinical Oncological Center, The Khabarovsk branch of the S. Fedorov Eye Microsurgery Federal State Institution
Summary:

Purpose: to improve the efcacy of surgical treatment of primary progressing pterygium by developing a new method of amnioplasty. Material and Methods. 85 patients were divided into two groups based on topographical features of amnioplasty site. The main group included 42 subjects who underwent amnioplasty using a technique which was proposed by us (after surgical removal of primary progressive pterygium at the initial site); the control group included 43 subjects in whom amnioplasty at the zone of limbus was performed after removing the pterygium. The criteria for evaluating treatment efcacy were time to disappearance of symptoms of postoperative infammation, time to complete corneal epithelialization and vitalization of the amnion, visual acuity in the frst year after surgery, reduction of corneal astigmatism, recurrence rate. Results. Amnioplasty technique proposed by us showed high efcacy: time of postoperative ocular surface infammation decreased, which led to an increase in corneal epithelization rate by 1.7 times and in amnion vitalization rate by 1.2 times; reduction of astigmatism by 3 times and an increase in visual acuity by 3.9 times when compared to the control group. Conclusion.

AttachmentSize
2019_02-1_428-433.pdf552.22 KB