Saratov JOURNAL of Medical and Scientific Research

autonomic dysfunction

Autonomic cardiac support in young males with arterial hypertension syndrome according to the type of hemodynamic response to physical exercise

Year: 2020, volume 16 Issue: №3 Pages: 728-736
Heading: Cardiology Article type: Original article
Authors: Zayats A.N., Shyshko V.I.
Organization: Grodno State Medical University

Objective: To evaluate the clinical and instrumental signs of autonomic dysfunction in young men with arterial hypertension (AH) syndrome depending on the type of hemodynamic response (TGR) to dosed physical activity. Material and Methods. Veloergometry (VEM) and cardiovascular testing (CVT) were performed in 208 men aged 18-29 years: 22 men in the control group, 34 men with physiological TGR, 52 men with hyperreactive TGR, 53 men with hypertensive TGR, 45 men with hyperdynamicTGO (HDTGR). Results: Clinical manifestation of autonomic dysfunction was present in less than 1/3 of patients regardless of TGR. In the HDTGR group SDNN was 36 (30; 54) ms, LF —605(363; 1073) ms2/Hz, HF — 322(160; 947) ms2/Hz and were significantly less than in other groups. According to the CVTdata, there was a paradoxical SDNN 1.2 times increase, the absence of HF and %VLF dynamics. Conclusion: Autonomic support is mostly disturbed in HDTGR, and is accompanied by a significant strain of the regulatory systems, hyporeactivity of the central regulatory mechanism and vagal unresponsiveness with a paradoxical SDNN increase.

2020_03_728-736.pdf560.03 KB

Autonomic dysfunction in patients with chronic cerebral ischemia

Year: 2019, volume 15 Issue: №1 Pages: 167-172
Heading: Neurology Article type: Original article
Authors: Poverennova I.E., Khivintseva E.V., Zakharov A.V., Vasemazova E.N., Ananyeva S.A.
Organization: Samara State Medical University

Various autonomic nervous system (ANS) disorders exist in 25-80% of the general population. Seniors affected by chronic cerebral ischemia (CCI) are subject to the development of autonomic disorders. Purpose: to carry out the analysis of autonomic dysfunction in subjects with CCI. Material and Methods. Autonomic status was evaluated using autonomic function tests. All patients underwent cardiointervalography. Heart rhythm variability was estimated by mode, amplitude, variation range, power of waves of various frequency, coefficient of vagosympathetic balance etc. as measured by "Rhythm-MET" system. One hundred fifty one patients aged 48-93 years were examined and distributed to three groups depending on the degree of severity of CCI. Results were statistically processed using Statistica 6 software. Results. Patients with CCI had differences in autonomic function parameters which had multidirectional character and were dependent on sympathetic-parasympathetic balance and CCI stage. The obtained data demonstrate that prevalence of sympathetic influence was observed in 52.8% patients with I grade CCI, in 64.8% patients with II grade CCI and prevalence of parasympathetic

2019_01-1_167-172.pdf254.8 KB