Saratov JOURNAL of Medical and Scientific Research

antiepileptic drugs

Issues of epidemiology of epilepsy in the Republic of Bashkortostan

Year: 2019, volume 15 Issue: №1 Pages: 163-166
Heading: Neurology Article type: Original article
Authors: Novikova L.B., Akopyan А.Р., Sharapova K.M.
Organization: Bashkir State Medical University of the Russian Health Care

Objective: to analyze the prevalence of epilepsy among adult population and the use of antiepileptic drugs (AED) in the Republic of Bashkortostan (RB) in 2013-2017. Material and Methods. Analysis of prevalence of etiological forms of epilepsy and used AEDs was carried out by analyzing data from annual reports of the neurological service of outpatient and inpatient medical institutions in cities and regions of the Republic of Bashkortostan, data of clinical examination of patients with a reliable diagnosis of epilepsy, as well as data from the Medical Information and Analytical Center (MIAC). Results. The prevalence of epilepsy in the Republic of Bashkortostan for the study period was 291.7- 325.8 case per 100 thousand population, which were most often recorded in central and eastern regions of the republic. The average age of patients ranged from 30.5±1.3to 41.8±0.2year. The ratio of men to women was approximately similar: 1.1:1.0. Cases of symptomatic epilepsy ranged from 82.6 to 46.5%. Among AEDs, carbamazepine was mainly used with a frequency of up to 47.4% and valproic acid with a frequency up to 32.9%. New generation drugs (parampanel) were rarely used (2.4%). Conclusion. The study of clinical and epidemiological characteristics of epilepsy is important for systemic organization of specific therapeutic and diagnostic measures and the creation of a specialized service to improve the quality of life of patients with epilepsy.

2019_01-1_163-166.pdf529.8 KB