Saratov JOURNAL of Medical and Scientific Research

corneal burn

Oxidative stress and methods of its correction in corneal burns (review)

Year: 2020, volume 16 Issue: №2 Pages: 459-463
Heading: Ophtalmology Article type: Review
Authors: Kolesnikov A.V., Kirsanova I.V., Sokolova A.I., Ban E.M.
Organization: Ryazan State Medical University n.a. I.L.Pavlov

The article presents actual ideas about the role of oxidative stress in the pathogenesis of corneal burns and methods of its correction. Corneal burns are rather common ophthalmic pathology. Corneal burns are difficult to treat, so they often lead to a decrease in visual acuity and, as a result, disability of young people. Despite the high antioxidant protection of the eye structures, under the influence of damaging environmental factors on the cornea (ultraviolet, chemicals, high temperatures, etc.), there is an increase in the concentration of free radicals with a decrease in the level of antioxidants — oxidative stress develops, aggravating damage to the cornea. Medicaments with antioxidant properties have shown their efficacy in the treatment of corneal burns.

2020_02_459-463.pdf341.36 KB

The thermal safety of system for ultrasonic aspiration of lens cortex

Year: 2018, volume 14 Issue: №4 Pages: 919-922
Heading: Ophtalmology Article type: Original article
Authors: Idrisova G.M.
Organization: Bashkir State Medical University of the Russian Health Care

The purpose of work is an experimental evaluation of the thermal safety of system for aspiration of lens cortex with the possibility of additional dosed low power ultrasonic. Material and Methods. The system for aspiration of cortex with the possibility of additional dosed low power ultrasonic consists of a specially designed ultrasonic instrument with a 21G tip and irrigation instrument with a 21G tip. Remote infrared thermometry (thermal imager Testo 882, Germany) was performed. In experiments a pig eyes were used (n=10). The eye was fixed in a titanium eye-holder, the tip of the ultrasonic instrument was inserted up through a 1.1 mm paracentesis on the meridian for 9 hours, the irrigation tip on the meridian for 3 hours. The initial temperature was recorded after irrigation and aspiration activation. Then ultrasound was activated (power 30%, activation time 10 s) and the final temperature was recorded. The rise in temperature was estimated as the difference between the final and initial temperatures. The software Testo IRSoft version 4.3 was used to process the images. Results. The average temperature rise in all experiment was 5.1±1.4°C. The maximum recorded temperature in the experiments were 33.5°C. Conclusion. Critical level of temperature for corneal burns was not reached in all of experiments. Conducted thermometric studies allow to conclude that the developed system for aspiration of lens cortex with the possibility of additional dosed low power ultrasonic is thermally safe.

2018_4-2_919-922.pdf732.86 KB