Saratov JOURNAL of Medical and Scientific Research

Makarov N.S.

Saratov State Medical University, Department of Neurology of Raising Skills Faculty, Assistant, Candidate of Medical Science

Clinical case of the manifestation of Parkinson's disease in a patient with neuro-leptic-induced parkinsonism

Year: 2019, volume 15 Issue: №1 Pages: 199-202
Heading: Neurology Article type: Case report
Authors: Yudina V.V., Makarov N.S., Yudina G.K.
Organization: Saratov State Medical University
Summary:

The article presents data on the mechanisms of development of drug-induced parkinsonism in patients taking neu-roleptic drugs, as well as on specifics of the development of Parkinson's disease in these patients. A clinical case of Parkinson's disease development in a patient with drug-induced parkinsonism who has been taken antipsychotics for a long time is described.

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"Benign" multiple sclerosis: a variant of favorable disease course and the result of effective treatment

Year: 2018, volume 14 Issue: №1 Pages: 153-156
Heading: Neurology Article type: Review
Authors: Makarov N.S., Kolokolov O.V.
Organization: Saratov State Medical University
Summary:

The article provides an overview of data on isolated demyelination syndromes that may precede multiple sclerosis, and on the peculiarities of the so-called "benign" form of multiple sclerosis. Clinical and anamnestic criteria for establishing the fact of a "benign" form of multiple sclerosis are presented, as well as trends in the number of these patients in the general population of patients with multiple sclerosis, including in connection with the improvement of treatment methods for this disease.

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Differential diagnosis of optic-spinal multiple sclerosis variant and Devic's disease among Mongoloid race representatives

Year: 2017, volume 13 Issue: №1 Pages: 155-157
Heading: Neurology Article type: Case report
Authors: Makarov N.S.
Organization: Saratov State Medical University
Summary:

The article provides an overview of the information on the racial peculiarities of some demyelinating diseases of the representatives of Asian nationalities and related methodological difficulties of differential diagnosis. Pay attention to a clinical example of a diagnostic situation.

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Nervous system diseases comorbid to psoriasis

Year: 2016, volume 12 Issue: №2 Pages: 300-303
Heading: Neurology Article type: Review
Authors: Fisun A.V., Kolokolov O.V., Bakulev A.L., Makarov N.S., Kravchenya S.S., Schabogina A.A., Popova O.V.
Organization: Saratov State Medical University
Summary:

The information about the cormorbid pathology in patients with skin and nervous systems diseases is summarized on the base of Russian and foreign scientific literature. The main attention is devoted to the combination of nervous system pathology with psoriasis and psoriatic arthritis. The high risk of cerebrovascular diseases development is pointed in psoriasis. Material concerning neuropathy caused by the cytostatics usage is represented in patients with psoriasis.

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Rare forms neurological disorders in an HIV-infected patient

Year: 2016, volume 12 Issue: №2 Pages: 296-299
Heading: Neurology Article type: Case report
Authors: Sotskova V.A., Kolokolov O.V., Shuldyakov А.А., Makarov N.S.
Organization: Saratov State Medical University
Summary:

The study aims paying the attention of specialists in rare cases of pathology of the nervous system in HIV-infected patients. The clinical case of brain abscess in a 32 year-old HIV-positive patient. Against the background of the surgical and antiretroviral treatment of brain abscess in HIV-positive patients it managed to achieve a virologic response and regression of neurological symptoms. Presented clinical case can be useful for specialists in determining the tactics of treatment of brain abscess in HIV-infected patients.

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Headache features in persons with anxiety disorders

Year: 2016, volume 12 Issue: №2 Pages: 270-273
Heading: Neurology Article type: Original article
Authors: Lukina E.V., Rusanova A.M., Makarov N.S.
Organization: Saratov State Medical University
Summary:

The aim of the article is to estimate the impact of anxiety on personality characteristics of headache in young adults studying full-time. Material and Methods. We observed 92 people aged from 15 to 25 years old, socially adapted, students in schools, colleges and universities on a full-time offices. Results. The perception of headache strongly depends on the emotional state of the individual, so it is very important to take this into account in the analysis of complaints and anamnesis of patients. Conclusion. Anxiety personality disorders hinder objectifying cephalgia, leading to misdiagnosis and incorrect treatment tactically with the possible development of abuse headaches. Therefore, it is necessary to convey to the patient the importance of reducing the impact of modifiable risk factors to explain the relationship of his condition with these factors and create a positive attitude to treatment.

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Clinical aspects and characteristics of the course of Parkinson’s disease with chronic cerebral ischemia

Year: 2012, volume 8 Issue: №2 Pages: 491-494
Heading: Neurology Article type: Original article
Authors: Makarov N.S., Spiridonova S.V., Voskresenskaya O.N.
Organization: Clinical hospital n.a. S. R. Mirotvortsev SSMU, First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The article is devoted characteristics current of Parkinson’s disease with chronic cerebral ischemia. Objective: to study the clinical presentation and features of PD against cerebral ischemia. Methods. A total of 44 patients with a diagnosis of “Parkinson’s disease”, 20 of which were determined by accurate clinical and instrumental signs of chronic cerebral ischemia. Comparative characteristics of the neurological status, cognitive functions, some laboratory and instrumental data in the two groups of patients: Parkinson’s disease with a background of chronic ischemia of the brain and without it. Results. Statistically signifcant differences between groups are observed on the following variables: duration of illness, severity of depression, the concentration of glucose in the blood. Formed groups of signifcant difference in the severity of atherosclerosis of cerebral vessels. Conclusion. The data of the acceleration of the progression of Parkinson’s disease with chronic cerebral ischemia, as well as the more frequent occurrence of depression in this patient group.

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Ninetieth Anniversary of Parkinson’s Disease «Substantia Nigra» Theory

Year: 2009, volume 5 Issue: №2 Pages: 279-282
Heading: History of Medicine. Anniversary Dates Article type: Review
Authors: V.V. Yudina, N.S. Makarov, G.K. Yudina, L.A. Kabanova, O.N. Voskresenskaya
Organization: Saratov State Medical University
Summary:

Article is devoted to the Ninetieth Anniversary of Creation of the «substantia nigra» theory of Parkinson’s disease by famous Saratov scientist K. N. Tretjakov.

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