Saratov JOURNAL of Medical and Scientific Research

Latypova E.A.

Bashkir State Medical University, Department of Ophthalmology with Postgraduate course, Associate Professor, PhD

Comorbidity of diseases of the cardiovascular system and primary open-angle glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 949-953
Heading: Ophtalmology Article type: Review
Authors: Zagidullina A.Sh., Latypova Е.А., Nugmanova A.R.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

This literature review examines the potential diagnostic contribution of syndromes and cardiovascular diseases: hypertension, atherosclerosis, vascular dystonia, and cerebrovascular pathology in the development of primary open-angle glaucoma (POAG). The study of relationships is relevant due to the commonality of some pathogenetic factors of POAG and these diseases and syndromes. It is necessary to take into account the effect of comorbid pathology in the early diagnosis of POAG, which will improve its quality, and the correction of associated disorders will contribute to the effectiveness of complex treatment of the disease.

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Bilateral acute generalized uveitis with Vogt-Koyanagi-Harada Syndrome

Year: 2018, volume 14 Issue: №4 Pages: 886-891
Heading: Ophtalmology Article type: Case report
Authors: Latypova Е.А.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

This study presents a case of bilateral generalized uveitis with exudative retinal detachment and Vogt- Koyanagi-Harada syndrome with a severe fulminant course in 27 year-old man with underlying neurological manifestations and hearing loss. The delayed diagnosis of the disease led to the rapid development of the late stage of uveitis with depigmentation of the fundus in the form of the "setting sun", persistent reduction of vision and complications with development of cataract, ophthalmic hypertension, epiretinal synechia and relapses. High-dose corticosteroids and immunosuppressive therapy allowed to achieve a positive effect and partially restore visual functions. Uveitis with a symmetrical lesion in both eyes is often an ophthalmological manifestation of systemic diseases. When it develops in individuals with darker skin pigmentation it is necessary to bear in mind the Vogt- Koyanagi-Harad syndrome.

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Aggressive posterior retinopathy of prematurity in a child conceived by in vitro fertilization

Year: 2018, volume 14 Issue: №4 Pages: 882-885
Heading: Ophtalmology Article type: Case report
Authors: Latypova E.A., Somova A.B., Matryuk D.I., Abdrakhmanova Yu.A.
Organization: Bashkir State Medical University of the Russian Health Care, «Republican Children's Clinical Hospital», Ufa
Summary:

Aggressive posterior retinopathy of prematurity (AP-ROP) is the most severe form ofretinopathy of prematurity (RP), characterized by early onset, fulminant course with absence of stagingand resistance to treatment. Today, the increase in AP-ROPincidence is associated with the changing standards for nursingof severely premature infants and wideprevalence of assisted reproductive technology — in vitro fertilization (IVF). The article presents a clinical case of aggressiveposterior retinopathy of prematurity in a girl with agestational ageof 25 weeks and a birth weightof about 860 grams who was conceived by IVF. Medical and high-tech laser treatment, fullycarried out in time, has lead toregression of this disease, which mayallowto preserve and develop visual function.

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Results of treatment of optic neuritis

Year: 2018, volume 14 Issue: №4 Pages: 875-879
Heading: Ophtalmology Article type: Original article
Authors: Latypova Е.А.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Purpose: to investigate the epidemiological and clinical features of optic neuritis, evaluate the effectiveness of treatment and underlying diseases. Material and Methods. 58 patients (60 eyes) with optic neuritis (ON) were observed. Among them, 54 adults (26 men, 28 women) aged 19-67 years (mean age 36±11.8 years) and 4 children (1 boy, 3 girls) 14-16 years. Along with the standard ophthalmologic examination, electrophysiological studies, visual evoked potentials and magnetic resonance imaging of the brain and orbit, and a consultation with a neurologist were conducted. The patients were divided into two groups. In the main group of 32 patients (34 eyes), the complex treatment is carried out according to the developed method, which includes daily administration of 1 % nicotinic acid solution in the age dose (from 1 ml to 6 ml per day) with pentoxifylline on the background of basic ON therapy. In the control group of 26 patients (26 eyes), along with basic therapy of 1% nicotinic acid, 1 ml intramuscularly is prescribed a course of 10-15 days. Results. The number of children of young working age (65.5%), including children (6.9%). In the overwhelming number of cases, intrabulbar neuritis was diagnosed (84.5%). In 8 of 9 patients, the precursor of retrobulbar neuritis (PN) was multiple sclerosis (MS). Among other etiological causes of ON viral infection prevailed (37.9%). In patients prolonged by the proposed method, an improvement in visual functions (increased visual acuity, expansion of the general boundaries of the visual field) was achieved in 91% of cases, including high vision (0.5-1.0) in 65% of cases; in patients of the control group, these indicators correspond to 54% and 23%. Conclusion. The use of nicotinic acid intravenously in age dosage with pentoxifyllone in complexes with basic therapy allows the use of methods of treatment of optical neuritis using etiology and can be recommended for widespread use in practical ophthalmology.

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Central retinal vein thrombosis in a patient with newly diagnosed congenital thrombophilia

Year: 2018, volume 14 Issue: №4 Pages: 872-875
Heading: Ophtalmology Article type: Case report
Authors: Latypova E.A., Zagidullina A.Sh., Yamlikhanov A.G., Arslanova A.l., Nugmanova A.R.
Organization: Bashkir State Medical University of the Russian Health Care, City clinical hospital 10 Ufa
Summary:

To date the etiology and pathogenesis of retinal vein thrombosis have not been fully studied despite a large body of scientific research. The article describes a rare clinical case of central retinal vein thrombosis in a 52-year-old man with newly diagnosed congenital thrombophilia.

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