Saratov JOURNAL of Medical and Scientific Research

Kirov State Medical University

Informativeness of optical coherence tomography in differential diagnosis of central chorioretinitis and age-related macular degeneration

Year: 2019, volume 15 Issue: №2 Pages: 524-528
Heading: Ophtalmology Article type: Original article
Authors: Popova L.I., Kudryavtseva Yu.V., Demakova L.V., Obsekova K.S.
Organization: Kirov State Medical University
Summary:

Purpose: the analysis of the informativeness of optical coherence tomography as an additional method in the diferential diagnosis of central chorioretinitis and age-related macular degeneration. Material and Methods. Studies conducted in 44 patients. The frst group included 20 patients with central chorioretinitis. The second group consisted of 24 patients with diferent forms of age-related macular degeneration. The informativeness of optical coherence tomography was analyzed in the diferential diagnosis of central chorioretinitis and AMD. Results. Uncomplicated forms of AMD and central chorioretinitis have a diferent tomographic picture. Using the OCT method it is possible to judge the change in the thickness of the choroid which increases in the acute phase of chorioretinitis. In the atrophic form of AMD, the thinning of the choroid extends over a considerable distance. OCT provides additional information on the localization of the infammatory focus. Conclusion. OCT-diferences were found at the level of the pigment epithelium, retinal photoreceptors and choroid in infammatory processes and degenerative diseases, which can help in difcult cases of diferential diagnosis. However, secondary choroidal neovascularization does not have specifc OCT signs in various diseases, since it is a complication of the main process.

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To the question of diferential diagnostics of secondary phacogenic glaucomas with a small anterior chamber

Year: 2019, volume 15 Issue: №2 Pages: 474-477
Heading: Ophtalmology Article type: Original article
Authors: Zamyrov A.A., Gavrilova I.A., Demakova L.V.
Organization: Kirov State Medical University, Kirov State Ophthalmology Hospital, «Sozvezdie» Ophtalmology Clinic
Summary:

Purpose: to determine diferential diagnostic criteria and surgical tactics in the treatment of swelling cataract and cataract in combination with subclinical lens subluxation associated with phacogenic glaucoma with a small anterior chamber. Material and Methods. Clinical traits and surgical treatment of 54 patients (54 eyes) were analyzed. Patients were divided in two groups. In patients of the frst group (32 eyes) the lens thickness did not difer from the paired eye. In patients of the second group (22 eyes) the diference was 1.1±0.3 mm. Results. In the frst group the mobility of the lens associated with a defect in the ligamentous apparatus was detected. In this case the methods of capsular bag stabilization were used. In the second group decrease in intraocular pressure and a deepening of the anterior chamber were noted after the opening of anterior lens chamber and evacuation of a part of cortical masses. Conclusion. In the diferential diagnosis of swelling cataract and cataract with subclinical lens subluxation the main criterion is signifcant between-eyes diference in the anteroposterior size of the lense according to the results of ultrasound biomicroscopy. Preoperative diferential diagnosis of swelling cataract and subclinical subluxation of the lens allows selecting the optimal surgical technique of cataract extraction and minimizing the possible complications. The method of simultaneous vitrectomy with transciliary access and cataract phacoemulsifcation is efective in treating of swelling cataract and cataract with subclinical subluxation of the lens associated with phacogenic glaucoma with small anterior chamber.

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Correction of the dry eye syndrome of professional etiology using a complex of mitochondrial substrates and co-factors

Year: 2018, volume 14 Issue: №4 Pages: 799-804
Heading: Ophtalmology Article type: Original article
Authors: Anisimova S.G., Mazina N.K., Abramova T.V.
Organization: Kirov Regional Clinical Hospital, Kirov State Medical University
Summary:

Aim: to evaluate the effect of the drug Cytoflavin (CFL), containing mitochondrial substrates and co- factors, on tear production in arc welders, gas welders and office workers with dry eye syndrome (DES). Material and Methods. 124 patients (248 eyes) with DES of professional etiology were enrolled in this study. Patients of the experimental group (CFL) took three 25-day courses of cytoflavin separated by 1 month intervals, while the control group received placebo. Results. Reception of CFL over 3-month cycles with intervals of 30 days contributed to an increase in visual acuity (VA) by 29,0-34,0%, Schirmer's test (ST) by 27.0-51.0%, and Norn's test (NT) by 7.5-11.0%, meniscus measurements (MM) by 32.0-37.0% and lower indices of intraocular pressure (IOP) by 3-5% in both occupational groups. Conclusion. The resulting increase in values of parameters characterizing the functional activity of the lacrimal gland under the action of the CFL suggest that pharmacological energy protection contributes to the improvement of tear production and eye hydrodynamics in welders and office workers.

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