Saratov JOURNAL of Medical and Scientific Research

botulinum toxin therapy

Strategy and tactics for cervical dystonia rehabilitation

Year: 2019, volume 15 Issue: №4 Pages: 968-970
Heading: Тhematic supplement Article type: Author's opinion
Authors: Anikina M.A., Bril Е.V., Zimnyakova O.S., Abbasov F.A.
Organization: State Research Center— Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Rehabilitation of patients with cervical dystonia is not limited to muscle relaxation, but includes comprehensive measures to correct motor and non-motor symptoms to achieve higher level of social adaptation. The article discusses the most effective rehabilitation techniques from the point of view of pathogenesis of dystonia, and highlights the problems related to the use of rehabilitation programs from the point of view of real clinical practice.

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EEG indicators of the central nervous system in individuals with different levels of psychophysiological adaptation

Year: 2019, volume 15 Issue: №4 Pages: 965-967
Heading: Brief Reviews Article type: Short message
Authors: Torubarov F.S., Zvereva Z.F., Lukyanova S.N.
Organization: State Research Center— Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The purpose of the study is to assess functional activity of the brain, individual structural and functional formations of the central nervous system at different levels of psychophysiological adaptation (PFA) and to identify their contribution to the formation of low PFA level. Material and Methods. Using psychological and visual-motor tests, methods of heart rate variability, functional state of structural and functional formations of the central nervous system: "cortex", "cortical-subcortical interaction", "central regulation of the cardiovascular system" was evaluated; the integral PFA level was determined using the evaluation results. EEG was used to evaluate brain functional activity and the listed CNS formations. Results. As the level of PFA in the EEG decreased, indicators regarded as the anomalous ones increased: type IV EEG; unstable EEG dynamics; high index of (31 activity; flashes of bilateral synchronous waves. The maximum number of abnormal EEG parameters was revealed at low FS of structural and functional formation "central regulation of the cardiovascular system" in persons with low PFA level. Conclusion. Identification of the maximum number of abnormal EEG indicators at low FS of structural and functional formation of the central nervous system "central regulation of the cardiovascular system" in persons with low PFA level testified to its main contribution to the formation of a low integral level of PFA.

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The effect of botulinum toxin type A injections on production of sebum in seborrhea

Year: 2018, volume 14 Issue: №4 Pages: 740-744
Heading: Dermatovenerology Article type: Original article
Authors: Kondrateva А.А., Galkina Е.М., Karakaeva A.V., Morrison A.V., Morrison V.V.
Organization: Saratov State Medical University
Summary:

 Aim: assessment of sebum production dynamics in patients who received treatment for mimic and static wrinkles in glabella and forehead regions with phase of a menstrual cycle taken into account. Material and Methods. We observed 15 female patients aged 24-38 years who received botulinum toxin therapy. Each BTX-Avial contained 100 units of lyophilized preparation. The solution of BTX-Awas prepared by mixing it with 2 ml of sterile saline. Five intramuscular injections with 2 U of BTX-A per point were made across the forehead, while 3 U injections were done in the glabellar area. The total amount of botulinum toxin used was 19 U per patient. Results. Maximum decrease in sebum production was observed 4 weeks after botulinum toxin injections, and return to baseline was observed at 16 weeks of follow-up. Conclusion. According to the obtained data, it may be stated that botulinum toxin injections affect sebum production with a maximum decrease observed at 4 weeks after botulinum toxin therapy.

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