Saratov JOURNAL of Medical and Scientific Research

cataract

Comparative characteristics of melatonin content in lacrimal fluid and blood serum depending on the stage of senile cataract with age-related macular degeneration

Year: 2020, volume 16 Issue: №2 Pages: 673-678
Heading: Ophtalmology Article type: Original article
Authors: Khodzhaev N.S., Chuprov A.D., Smolyagin A.I., Kim S.M., Filippova Yu.V.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

The purpose of the study is to evaluate factors affecting concentration of melatonin in the tear and blood serum in patients with a non-exudative form of age-related macular degeneration (AMD). Material and Methods. 140 patients (140 eyes) were examined, of which 52% were women, 48% were men. The following groups of patients were formed: 1) patients with non-exudative AMD and senile cataract who took melatonin; 2) patients with non-exudative AMD and senile cataract who did not take melatonin; 3) without AMD and cataract; 4) patients with non-exudative AMD, not requiring surgical treatment of cataract; 5) patients with neovascular (exudative) form of AMD (nAMD). The melatonin content was determined using immunosorbent assay. Results. The content of melatonin in all examined patients' serum ranged from 0.001 to 0.161 ng/ml, the highest median of melatonin values was observed in healthy individuals (0.125 ng/ml), and the lowest in patients with nAMD (0.021 ng/ml). The level of melatonin in the tear varies from 0.067 to 0.477 ng/ml, while its highest median was found in group 1 patients: 0.324 ng/ml. In group 2 and reference groups (without cataract with AMD and with nAMD), the melatonin content in the tear was significantly reduced (p <0.05) compared with the level in the group of healthy individuals. Conclusion. The content of melatonin in the blood serum and lacrimal fluid depends on the following factors: age, arterial hypertension, body mass index (BMI), insomnia, smoking, hair and eye color, night shifts. Using melatonin in the treatment of patients with AMD helps to increase the concentration of melatonin in tear.

AttachmentSize
2020_02-1_673-678.pdf355.68 KB

Analysis of the results of implanting intraocular lens with low-addition power and asymmetric optics

Year: 2020, volume 16 Issue: №2 Pages: 628-632
Heading: Ophtalmology Article type: Original article
Authors: Nenasheva Yu.V., Fabrikantov O.L.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution, Tambov State University n. a. G.R. Derzhavin
Summary:

The purpose of the study is to analyze clinical and functional treatment outcomes and usefulness of visual rehabilitation in patients implanted with IOL Lentis Comfort. Material and Methods. 64 patients were examined. Patients of group one underwent cataract phacoemulsification with IOL Lentis Comfort implantation, patients of group two were implanted with IOL Acrysof Restor. Non-corrected and corrected distance visual acuity, for intermediate distance (70 sm) and near visual acuity (30-40 sm) were examined on the 2nd day, in a month and in 6 months postoperatively. In 6 months after surgery subjective assessment of patients' satisfaction with the quality of vision was conducted using a questionnaire. Results. High distance visual acuity was revealed in both groups, visual acuity for intermediate distance was significantly higher in patients of group one, near visual acuity was higher in patients of group two. According to the questionnaire results patients of both groups did not experience difficulties in working and driving during the day, at night, patients of group two were much more likely to report difficulties in driving a car and undesirable light phenomena. Conclusion. Implantation of IOL with low-addition power and asymmetric optics provides high quality vision at various distances. The low level of undesirable light phenomena contributes to rapid adaptation of patients in the postoperative period.

AttachmentSize
2020_02-1_628-632.pdf408.87 KB

Polymer micro-shunt Reper-NN in combined glaucoma and cataract surgery

Year: 2020, volume 16 Issue: №1 Pages: 223-227
Heading: Ophtalmology Article type: Original article
Authors: Kolpakova О.А., Fabrikantov O.L., Nikolashin S.I.
Organization: Tambov State University n. a. G.R. Derzhavin, S. Fedorov Eye Microsurgery Federal State Institution
Summary:

The purpose of the study is to estimate the efficacy of polymer micro-shunt Reper-NN in combined glaucoma and cataract surgery. Material and Methods. The examination group consisted of 34 patients (34 eyes) with cataract and glaucoma of different stages. All patients were divided into 2 groups: 1)16 patients underwent micro-shunt Reper-NN implantation with simultaneous phacoemulsification with IOL implantation; 2) 18 patients underwent micro-invasive non-penetrating deep sclerectomy with simultaneous phacoemulsification with IOL implantation. The diagnosis was made based on the anamnesis and data of objective and instrumental examinations. Preoperatively all patients underwent examination of visual acuity, intraocular pressure, perimetry, ophthalmometry, ultrasound scanning. Results. Intraocular pressure was normalized in all patients. Conclusion. Combined cataract and glaucoma surgery using polymer micro-shunt Reper-NN is an effective and safe method of treating open-angle glaucoma and cataract.

AttachmentSize
2020_01-2_223-227.pdf330.82 KB

Diagnosis of retinocytoma in the eye with swelling mature cataract (clinical case)

Year: 2020, volume 16 Issue: №1 Pages: 31-33
Heading: Ophtalmology Article type: Case report
Authors: Krasyuk E.Yu., Ovchinnikov V.I.
Organization: Tambov Ophthalmological Clinical Hospital
Summary:

A clinical case of a rare retinocytoma tumor in a patient with swelling cataract and phacomorphic glaucoma is presented. A comprehensive examination of the patient using various diagnostic methods allowed to make the correct diagnosis and conduct timely surgical treatment with predictable results.

AttachmentSize
2020_01_031-033.pdf593.9 KB

Clinical and functional results of bifocal and trifocal intraocular lenses implantation: a comparative analysis

Year: 2019, volume 15 Issue: №2 Pages: 518-524
Heading: Ophtalmology Article type: Original article
Authors: Pershin K.B., Pashinova N.F., Konovalova M.M., Tsygankov A.Yu., Konovalov M.E.
Organization: Konovalov Eye Center, Ophthalmological clinics «Eximer»
Summary:

Purpose: comparative analysis of the results of implantation of bifocal refractive-difractive IOLs and new trifocal single-piece aspherical difractive IOLs. Material and Methods. A prospective open study included 193 patients (291 eyes) with presbyopia. The average age of patients was 58.4±11.3 years. Group I consisted of 71 patients (108 eyes) with implantation of the AcrySof PanOptix trifocal IOL; Group II — 122 patients (183 eyes) with the AcriSof Restor bifocal IOL with addidation 3 Dioptr. Results. After 6 months of follow-up in group I, an increase in UCNVA from 0.2±0.09 to 0.85±0.17, an UCFVA from 0.2±0.07 to 0.78±0.13, and a UCIVA from 0.3±0.1 to 0.84±0.2, BCNVA from 0.58±0.24 to 0.98±0.21, BCFVA from 0.68±0.26 to 1±0.1 and BCIVA with 0.59±0.28 to 0.95±0.18 (p<0.05 in all cases). In group II, signifcantly lower values of UCNVA (0.62±0.09), UCIVA (0.31±0.14) and BCIVA (0.6±0.19) were observed when compared with group I (p<0.05). In all groups, a decrease in the spherical and cylindrical component of refraction was observed. Level of contrast sensitivity after implantation of the AcrySof Restor was higher for all frequencies. According to the results of the survey on a scale of VF-14 in group I, the average value was 97.9±1.2 points, and in group II — 80.1±6.4 (p<0.05). Conclusion. In this paper an advantage of a new trifocal IOL for vision correction at an average distance under various lighting conditions is shown, as well as the best indicators of vision quality on the VF-14 scale.

AttachmentSize
2019_02-1_518-524.pdf865.31 KB

Effect of cataract phacoemulsification on the dynamics of intraocular pressure in patients with primary open-angle glaucoma

Year: 2018, volume 14 Issue: №4 Pages: 837-841
Heading: Ophtalmology Article type: Original article
Authors: Kolesnikov A.V., Kolesnikova M.A., Mironenko L.V., Baranova O.V., Tarasova N.S.
Organization: Ryazan State Medical University n.a. I.L.Pavlov, Regional Clinical Hospital n.a. N.A. Semashko
Summary:

Purpose: to assess the dynamics of intraocular pressure (IOP) after cataract phacoemulsification (CFE) with intraocular lens (IOL) implantation in patients with cataract in combination with primary open-angle glaucoma (POAG). Material and Methods. The subject of this study was the analysis of IOP after CFE in 65 patients (89 eyes) with cataract in combination with POAG. Among the examined patients, the initial stage of glaucoma was noted in 14.6% cases; developed stage in 55.1 % cases, far-reaching stage in 30.3% cases. IOP was compensated in 84.5% cases, and sub-compensated in hypotensive mode in 15.5% cases. The observation period was from 1 month up to 2 years. Results. In dependence of IOP after surgery, patients were divided into three groups: IOP exactly like in preoperative level, below and above the initial IOP In most cases, at all times IOP corresponded to the preoperative level and after 2 years it was noted in 77.4%. The number of patients with ophthalmotonus below the baseline (1-8 mm) decreased from 63.2% in 1-3 months after surgery to 16.1 % in two years. An increase in ophthalmotonus (by 3-4 mm) was noted in 27% of cases, however, a persistent increase in IOP, which required correction, was 7.9% at stage III of glaucoma, and in the rest of the eyes IOP normalized by itself. Conclusion. According to the results of the study, it can be concluded that there is an ambiguous effect of CFE with IOL implantation on IOP in patients with cataract in combination with POAG, which necessitates further study.

AttachmentSize
2018_4-2_837-841.pdf279.08 KB

Lens densitometry in ultrasonic cataract phacoemulsification

Year: 2018, volume 14 Issue: №4 Pages: 815-817
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Dibaev T.l., Munasypova V/V., Khamidov U.B., Mukhamadeeva O.R.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Purpose: to evaluate the effectiveness of using Pentacam HR sheimpflug camera for objective determination of cataract density. Material and Methods. The subject of the study was the method of determining the density of the lens (densitometry) by the Pentacam HR sheimpflug-camera. The object of the study were patients with age-related cataracts (147 eyes). All patients underwent ultrasound phacoemulsification with implantation of various types of intraocular lenses (IOL). Before treatment, the density of the lens was determined by non-contact method using PNS (Pentacam Nucleus Staging). During the surgery, the density of the lens was determined by the surgeon on a set of factors: the color of the nucleus, the mechanical density, the emulsification easiness. The equivalent ultrasound time and the fact of compliance or discrepancy in the degree of density of the lens with two methods of its determination were recorded for each patient. Results. It was found that the density of the lens recorded by the Pentacam HR is in a direct strong correlation with the equivalent ultrasound time. It was shown that the discrepancy between the PNS method and the contact method performed by the surgeon significantly lengthens the surgery time. Conclusion. The Pentacam HR sheimpflug-camera is an accurate method of determining the density of the cataract before the surgery. The advantage of this method is that it is non-contact, quick and relatively easy-to-perform with the possibility of objective assessment.

AttachmentSize
2018_4-2_815-817.pdf242.74 KB

Clinical performance of system for ultrasonic cortex aspiration during phacoemulsification

Year: 2018, volume 14 Issue: №4 Pages: 811-815
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Dibaev T.I., Mukhamadeev T.R., Idrisova G.M.
Organization: Bashkir State Medical University of the Russian Health Care, ZAO Optimedservis
Summary:

Purpose: to study the performance and safety of the use of system for cortex aspiration with the possibility of additional dosed low power ultrasound during phacoemulsification. Material and Methods. The comparative evaluation of developed system for cortex aspiration with the possibility of additional dosed low power ultrasound (main group, n=36, ophthalmological surgical platform Optimed Profi) and the traditional system for cortex aspiration (control group, n=40, ophthalmological surgical platform Centurion Vision System) were performed. Results. Using the system for cortex aspiration decreases mean time of cortex aspiration. In the main group the mean time of cortex aspiration was 72.6±24.3 s, in the control group 93.9±48.0 s (p<0.05). Intraoperative complications were not observed in the main group. Posterior capsule rupture was detected during the cortex aspiration in 1 patient (2.5%) in the control group. Conclusion. The system for cortex aspiration with the possibility of additional dosed low power ultrasound allows decrease the time of cortex aspiration, to create conditions for a safer removal of cortex, compared with traditional technology.

AttachmentSize
2018_4-2_811-815.pdf636.91 KB

Analysis of incidence of eye and adnexa diseases in the Central Black Earth region

Year: 2018, volume 14 Issue: №4 Pages: 670-676
Heading: Ophtalmology Article type: Original article
Authors: Osmanov RE, Zhabina UV, Manyakov RR, Osmanov EM.
Organization: S. Fedorov Eye Microsurgery Federal State Institution, Tambov State University n. a. G.R. Derzhavin
Summary:

The purpose is to study the dynamics of general and primary incidence of eye diseases and accessory apparatus among the population of the Central Black Earth region for the period 2008-2017, in comparison with similar indicators in the Russian Federation. Material and Methods. The article presents the data on the dynamics of general and primary incidence of eye diseases as a whole, as well as myopia and cataracts in comparison with Russia and the five regions of the Central Black Earth region (Belgorod, Voronezh, Kursk, Lipetsk, Tambov) from 2008 till 2017 Results. A comparative analysis of morbidity indicators allowed us to identify regions that are unfavorable for ocular morbidity in general and for cataracts and myopia in particular. Conclusion. The total incidence of eye diseases among the population of Russia in 2008 accounted 10994,0±2,6 cases, over ten years there was a decrease to 10370,9±2,5 cases per 100000 persons. The primary incidence rate of eye diseases among the population of Russia in 2008 accounted 3422±1,5 cases, over a ten-year period there was a decrease to 3161,1±1,4 cases per 100000 persons. Among the regions of the Central Black Earth region in the Belgorod region, the indicators studied are higher than the average in Russia. The incidence of eye diseases, in particular, cataracts and myopia tends to decrease. However, its level remains significantly high, which requires the improvement of organization of eye care and the development of measures aimed at preventing the development of eye pathology.

AttachmentSize
2018_4_670-676.pdf1.67 MB