Khmilevskaya S.A.

The review presents literature data on the catamnesis of children born with extremely low and very low weight, identification of the most common pathological conditions, of the incidence rate and the main causes of disability in childhood, the rationale for the need for early initiation of rehabilitation actions aimed at preventing and correction of these conditions. The article highlights difficulties in assessment of physical and neuropsychological development of deeply premature babies, related to the heterogeneity of contingent of the children being surveyed and the difference in the tests used to determine these parameters. It was noted that for a comprehensive assessment of their health they also need to determine quality of life using the developed scales. The author substantiated the need to improve the system of medical support for such children at all phases of nursing and rehabilitation process and perforce to introduce a personal approach with differentiated programs of medical examination and rehabilitation in the wide practice.

The article reviews the results of observation of 439 patients between 1 and 18 years of age with EBV mononucleosis. The detailed analysis of clinical laboratory peculiarities of primary infection and its reactivation in patients of different age is also supplemented by the overall evaluation of the rehabilitation period in dependence on age and type of infection.

The research presents the results of medical observation of 439 patients aged 1-18 with mononucleosis of Epstein-Barr Virus etiology. By means of instrumental and clinical laboratory methods of investigation the peculiarities of liver condition have been revealed in children of different age. The intensity of autosensibilization processes to the tissues of the organ has also been estimated. The results obtained demonstrate the interrelation of clinical, biochemical and instrumental signs of liver damage, as well as contribution of autoimmune processes to the development of organopa-thology at Epstein-Barr Virus infection

The research results are presented in the work. 100 patients aged 1–18 with different Epstein-Barr viral infection course variations have been observed. Clinical features of infectious mononucleosis in case of primary infection and its revivification have been revealed. The evaluation of intensity of autosensibilization processes has been performed. The interrelation of autoimmune and cytokine reactions and their participation in formation of organopathology in case of Epstein-Barr viral infection are demonstrated.