Saratov JOURNAL of Medical and Scientific Research

risk factors

Clinical and instrumental risk factors for epileptic seizures in patients after traumatic brain injury

Year: 2016, volume 12 Issue: №3 Pages: 366-370
Heading: Neurology Article type: Original article
Authors: Zakharov A.V., Poverennova I.E., Kurov M.V., Khivintseva E.M.
Organization: Samara State Medical University
Summary:

The aim: analysis of factors influencing the risks of posttraumatic epilepsy (РТЕ). Materials and Methods. The study involved 71 patients with traumatic brain injury of moderate and severe with emerging after her epileptic seizures. Among the subjects was 56 (78.9%) males and 15 (21.1%) females. The average age of the subjects was 65.6±10,3 years. The control group was 25 (71.4%) male patients and 10 (28.6%) females. The average age of the patients was 54.4.±9.3 years. Analysis of factors influencing the risks of РТЕ use nonparametric Spearman correlation and multivari-ate analysis of variance. Results. Among the many factors to be statistically significant risk factors for РТЕ was alcohol intoxication at the time of trauma 27 (38,0%), relative to the control group 2 (5.7%) p

AttachmentSize
2016_03_366-370.pdf262.42 KB

Gender features of risk factors and clinical course of arterial hypertension

Year: 2015, volume 11 Issue: №4 Pages: 542-547
Heading: cardiac surgery Article type: Original article
Authors: Shkatova E.Yu., Bakshaev I.N., Korolkova G.S.
Organization: Igevsk State Medical Academy
Summary:

The aim of the article is to reveal the risk factors and features of the clinical course of hypertension in men and women. Material and Methods: A prospective study of 204 patients was carried out. The survey included a sociological survey, with the use of special socio-sanitary profiles, matters which concern lifestyle characteristics of respondents, hereditary risk factors, peculiarities of hypertension. Results: Men often have a hidden crisis-free for hypertension with a great number of complications; women have a longer duration of the disease, with a more severe clinical picture. Conclusion: The differences of social and health behavior with the existing risk factors and the clinical course of hypertension according to the gender of the patient have been revealed.

AttachmentSize
2015_04_542-547.pdf298.37 KB

Sclerotic disease, integrative diagnosis, chronic forms and treatment of diseases

Year: 2015, volume 11 Issue: №3 Pages: 268-274
Heading: Internal Diseases Article type: Review
Authors: Kats Ya.A., Parkhoniuk E.V., Skriptsova S.A.
Organization: Saratov State Medical University
Summary:

The aim of the article is to determine the importance of an integrative approach to identify and analyze the phases or stages of the example of chronic sclerotic disease (CSD). The proposed concept of CSD is to use the diagnostic methods before sclerotic period, based on an analysis of indicators of intensity of the functional systems responsible for collagen formation and collagen lysis taking into account the potential of genetically caused features of sclerosis. Thus, special attention is paid to pre-disease stage including the history and molecular genetic studies which predict the nature of the possible diseases and determine the risk of formation of CSD. The proposed methodology and techniques, as well as obtained with their help data define the possibility of risk groups identification, the direction and volume of the survey.

AttachmentSize
2015_03_268-274.pdf308.47 KB

Hospital registry in special department for patients with acute cerebrovascular disease

Year: 2014, volume 10 Issue: №4 Pages: 819-823
Heading: cardiac surgery Article type: Original article
Authors: Maslyuk О.А., Smolentseva I.G., Amosova N.A., Krivonos O.V., Shevchenko N.S., Milagina V.S.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Aim: organization and follow-up of a registry of patients with cerebrovascular disease in in special department. Materials and methods. In the period from January 2011 to December 2013 all cases of cerebrovascular disease in the special department were recorded. Each patient had an electronic case book and thematic record, developed on the basis of the materials of the National Stoke Association of "Registry of stroke." Results. 418 cases of cerebral stroke were registered. Male to female ratio was 3.7: 1. Patients with initial diagnosed cerebral stroke were 78%, secondary 22%. The average age of patients was 63. The big number of strokes was observed in men aged 56-57 years; in women aged 75-77 years. TOAST criteria for subtypes of ischemic stroke were distributed to: atherothrombotic (29,3%), cardioembolic (29,1 %), 22,4% lacunar ischemic stroke due to other established reasons (8,8%), crptogenic (10,4%). Hemorrhagic stroke was observed in 16.8% of cases. Parenchymal hemorrhage was observed in 10.7% of cases, nontraumatic subarachnoid hemorrhage (4,5%). Among the risk factors in patients with ischemic stroke identified: arterial hypertension (88,9%), coronary heart disease (43%), heart rhythm disorders (28,4%), diabetes (18,6%). The proportion of endovascular interventions performed for 3 years was 31.2%. Mortality rate was 3.74% (10 people) in 2011; 4.65% (14 people) in 2012; 2.48% (7 people) in 2013. Conclusion. Follow up the hospital stroke registry allowed to estimate the structure andcourse of cerebral stroke, found the risk factors to identify the most important factors of death.

AttachmentSize
2014_04-01_819-823.pdf327.1 KB

Retinopathies in premature infants, incidence, risk factors, prevention and treatment

Year: 2014, volume 10 Issue: №4 Pages: 688-691
Heading: Proceedings of all-Russia week of science with international participants Article type: Original article
Authors: Chernenkov Yu.V., Nechaev V.N., Tereshenko V.A., Rodionova O.A.
Organization: Saratov State Medical University, Saratov Perinatal Centre
Summary:

Research Objective: Analysis of incidence and accompanying states, detection of risk factors of retinopathies in premature infants (RN), dynamic monitoring and improvement of medical actions. Material and Methods: 134 children have been surveyed in the group of risk on development of RN for the last 2 years. Results: From 134 surveyed infants with gestation from 22 to 37 weeks and body weight at birth from 750 to 2500 kg. At 56 children (41,8%) the retinopathy of various degree of expressiveness has been revealed. 38 children with RN of 1-2 stages (67,8%) from which at 22 (39,3%) —the disease ended with the induced regress after a course of «retinalamin», at 16 (28,6% of RN) — spontaneous regress. 4 children (7,1%) had RN 2-3 of the Art., 3-4 Art. at 12 (21,4%), and 5 Art. a cicatricial phase with retinal detachment — 2 (3,5%). In 12 cases the laser photocoagulation in the eye centers is carried out. Conclusion: The revealed relationship of cause and effect of risk factors of formation of RN with features of a current ofthe neonatal period at patients with RN, promoted development of the system of monitoring, implementation of the program of treatment and rehabilitation of prematurely born children suffering RN. Ophthalmologic screening of premature infants with the use of the ophthalmologic digital pediatric camera "Ret Cam 3" allows to diagnose a retinopathy at early stages, in due time to hold preventive an3 medical measures that allows to lower the invalidization of this group of children.

AttachmentSize
2014_04_688-691.pdf297.21 KB

Assessment of health state of newborns depending on duration of waterless interval and infectious process at mother

Year: 2014, volume 10 Issue: №3 Pages: 427-431
Heading: Pediatrics Article type: Original article
Authors: Chernenkov Yu.V., Nechaev V.N., Lisitsyna A.S.
Organization: Saratov State Medical University
Summary:

Objective: to reveal and estimate dependence between a long waterless interval, infectious process at mother and pathology of newborn children. Material and Methods: Supervision and research have been carried out in Perinatal Center of Saratov region for the last 2 years. 167 women and 173 newborns were included in the research. The big group was composed by prematurely born children. Women were divided into 2 groups depending on infectious process of patrimonial ways and on duration of a waterless interval. Children were divided on gestation term. Results: fetoplacental insufficiency and threatened miscarriage are the main factors of extremely immature children birth. Under these conditions, prolongation of pregnancy and preparing a fetus to labor act are important factors for improving the adaptive capacity of a premature baby. One of the important factors of insolvency is membranes infection. It is a distinct disease or a result of complications of pregnancy prolongation in women with PROM, is a precursor of systemic inflammatory response and in the majority of newborns was realized in infectious process. Conclusion. Women with infectious pathology of birth canal should be thoroughly sanitized, preventive treatment should be carried out, it would prevent the implementation of fetus infection, reduce posthypoxic disorders and incidence of preterm birth and IUGR. Long PSU without infectious support contributes to a lesser extent implementation of infection in fetus and less effect on a child's neurological status.

AttachmentSize
2014_03_427-431.pdf352.38 KB

Assessment of health state of newborns depending on duration of waterless interval and infectious process at mother

Year: 2014, volume 10 Issue: №3 Pages: 427-431
Heading: Pediatrics Article type: Original article
Authors: Chernenkov Yu.V., Nechaev V.N., Lisitsyna A.S.
Organization: Saratov State Medical University
Summary:

Objective: to reveal and estimate dependence between a long waterless interval, infectious process at mother and pathology of newborn children. Material and Methods: Supervision and research have been carried out in Perinatal Center of Saratov region for the last 2 years. 167 women and 173 newborns were included in the research. The big group was composed by prematurely born children. Women were divided into 2 groups depending on infectious process of patrimonial ways and on duration of a waterless interval. Children were divided on gestation term. Results: fetoplacental insufficiency and threatened miscarriage are the main factors of extremely immature children birth. Under these conditions, prolongation of pregnancy and preparing a fetus to labor act are important factors for improving the adaptive capacity of a premature baby. One of the important factors of insolvency is membranes infection. It is a distinct disease or a result of complications of pregnancy prolongation in women with PROM, is a precursor of systemic inflammatory response and in the majority of newborns was realized in infectious process. Conclusion. Women with infectious pathology of birth canal should be thoroughly sanitized, preventive treatment should be carried out, it would prevent the implementation of fetus infection, reduce posthypoxic disorders and incidence of preterm birth and IUGR. Long PSU without infectious support contributes to a lesser extent implementation of infection in fetus and less effect on a child's neurological status.

AttachmentSize
2014_03_427-431.pdf352.38 KB

Scientific substantiation for the analysis of medical and social aspects of a healthy lifestyle as a basis of the effectiveness of rehabilitation in the modern conditions

Summary:

Efficiency of performed rehabilitation events in many respects depends on a state of health of the person which, in turn, directly depends on his/her medico-social activity. Aims: analysis of medico-social aspects of a healthy lifestyle of medical workers and patients of the center of recovery medicine and rehabilitation. Material and Methods. According to specially developed anonymous questionnaires there had been the research of the personnel (410 questionnaires) and patients (300 questionnaires) of the Center of recovery medicine and rehabilitation of Federal State Budgetary Institution Medical and Rehabilitation Center of Ministry of Health of Russia (TsVMR). Results. It is shown that the majority of participants regardless of professional functions and responsibilities understand an important role of healthy food and try to observe the correct diet, however, medical workers take this component of a healthy lifestyle more seriously. Thus the most part of citizens not having a direct bearing on health system are reluctant to care abot questions of healthy food, this emphasizes insufficiency of sanitary and hygienic education. Conclusion. Results of research can be used for development of scientific bases of increase of the efficiency of rehabilitation and recovery treatment in modern conditions.

AttachmentSize
2013_04-01_1009-1012.pdf263.45 KB

Colon polyps: epidemiology, risk factors, diagnostic criteria and courses of treatment

Year: 2013, volume 9 Issue: №2 Pages: 252-259
Heading: Internal Diseases Article type: Review
Authors: Lapteva Е.А., Kozlova I.V., Myalina J.N., Pakhomova A.N.
Organization: Saratov State Medical University
Summary:

Article focuses on the intestinal polyps. Intestinal polyps are considered to be obligatory precancerous diseases of the colon. Risk factors, epidemiology, clinical manifestations and diagnostic methods of polyps have been analyzed. The courses of treatment of colon polyps have been revealed.

AttachmentSize
2013-02_252-259.pdf287.99 KB

Evaluation of risk factors of infantile cerebral paralysis development in disabled children

Year: 2011, volume 7 Issue: №2 Pages: 446-450
Heading: Neurology Article type: Original article
Authors: Alekseeva G.Yu., Sholomov I.I.
Organization: Saratov State Medical University
Summary:

Research object: to detect the influence of qualitative and quantitative factors involved into ICP formation. Material: the research is based on the clinical observation, instrumental diagnostics and 147 disabled children with ICP aged under 4 rehabilitation campaign results analysis. Comparison group was composed from 39 children of similar age who were registered for observation by pediatric polyclinics neurologists and were rehabilitated. Results: 2 algorithms formed as decision trees, that were built using multivariate analysis methods were suggested and can be used in pediatric polyclinics for children with ICP formation threatening detection. Conclusion: the ICP formation can be forecasted in 93% of cases wrt prematurely born children with convulsive and hypertensive-hydrocephalic syndromes in aggregate with periventricular leukomalacia

AttachmentSize
201102_446-450.pdf737.28 KB