Saratov JOURNAL of Medical and Scientific Research

Fomina T.V.

State Research Center — Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Institute of Postgraduate Professional Education, Engineer researcher of the Laboratory of Non-ionizing Radiation

Experimental study of the bioeffects of micropolarization current as a result of the use of metallic conductors in irradiating a rabbit's head with electromagnetic field of non-thermal intensity

Year: 2019, volume 15 Issue: №4 Pages: 994-998
Heading: Тhematic supplement Article type: Original article
Authors: Lukyanova S.N., Fomina T.V., Veselovskiy I.A.
Organization: State Research Center— Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The purpose of the study is to experimentally evaluate the impact of metal electrodes and wires on the brain bioelectric activity indicators as a result of rabbit head irradiation with electromagnetic field (EMF) of non-thermal intensity. Material and Methods. Studies conducted on rabbits. Electromagnetic field: 10 GHz, continuous mode, PPS 200 mW/cm2, created by the high-frequency signal generator G4-121 with repeated exposures with different durations. Results. The probability of the development of the effects of current micropolarization is shown when using metallic conductors, which changes the result of the EMF action. It depends on the number of electrodes and the location of wires relative to the field lines. Conclusion. We substantiated the possibility of the influence of metal electrodes on the bioelectrical activity of the brain by inducing a micropolar current under conditions of irradiation of the head with an electromagnetic field in the course of experiments on rabbits.

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Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats

Year: 2017, volume 13 Issue: №4 Pages: 901-907
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Datsenko A.V., Fomina T.V., Dyoshin I.A., Kazmin V.I.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Purpose: to determine the quantitative patterns and gradations of the degree of manifestation of changes in IRT indicators, depending on LDF data, corresponding to different conditions and peripheral blood flow disorders in the skin of laboratory rats. Material and Methods. Microcirculation of blood in bio-objects in background studies and immediately after the experimental modeling of hypobaric hypoxia was determined with the help of LDF, while simultaneously performing remote dynamic infrared thermography of the rats'tail skin. A comparison of LDF and IRT data was carried out using statistical methods of correlation-regression analysis. Results. The decrease in tissue blood flow was accompanied by a decrease in temperature, with an increase in perfusion of blood along the microcirculation pathways, the temperature of the skin surface increased. The quantitative criteria of experimental diagnostics in the form of boundary values and ranges of temperature indicators for an estimation of a different degree of severity of violations of the microcirculation of blood (peripheral hemodynamics) are determined. With a decrease or increase in tissue blood flow to 10, 10-25, 25-40 and more than 40% of the baseline (background control), the negative or positive skin surface temperature increase was up to 0.6, 0.6-1.2, 1.2-1.8 and more than 1.8°C respectively. Conclusion. Results of thermal imaging can be used as a criterion for predictive assessment of the state and changes in cutaneous peripheral blood flow in laboratory rats.

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