Saratov JOURNAL of Medical and Scientific Research

Nikitina N.M.

Saratov State Medical University n.a. V.I. Razumovsky, Department of Hospital Therapy of Medical Faculty, Professor, Doctor of Medical Science

Rituximab treatment efficacy in a patient with systemic lupus erythematosus with severe thrombocytopenia

Year: 2018, volume 14 Issue: №3 Pages: 417-419
Heading: rheumatology Article type: Case report
Authors: Alexandrova O.L., Nikitina N.M., Magdeeva N.A., Shmelkova M.Yu., Grigoryeva S.N.
Organization: Saratov Regional Clinical Hospital, Saratov State Medical University
Summary:

The article presents a clinical case of systemic lupus erythematosus with severe thrombocytopenia in a 55 year old patient. The standard therapy of usage of high doses of glucocorticoids, cyclophosphamide and intravenous im-munoglobulin was not effective. Application of Rituximab improved the course of disease, decreased the severity of thrombocytopenia, led to disappearance of leucopenia and anemia.

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Clinical case of favourable outcome at a patient with eosinophilic granulomatosis with polyangiitis complicated by severe heart disease

Year: 2018, volume 14 Issue: №2 Pages: 207-209
Heading: Internal Diseases Article type: Case report
Authors: Alexandrova O.L., Skryabina E.N., Nikitina N.M., Romanova I.A., Alexandrova N.L.
Organization: Saratov State Medical University
Summary:

The aim of the article is to present a clinical case of rapid generalization of eosinophilic granulomatosis with polyangiitis. The course of disease with multiple organ lesions and the heart being affected the most is described. Remission is achieved by combined therapy with corticosteroids and cyclophosphamide.

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A clinical case of fast progression of amyloidosis of kidneys in rheumatoid arthritis

Year: 2017, volume 13 Issue: №4 Pages: 821-823
Heading: Internal Diseases Article type: Case report
Authors: Romanova I.A., Magdeeva N.A., Nikitina N.M.
Organization: Saratov State Medical University
Summary:

The article presents clinical case of unfavorable outcome of amyloidosis of kidneys in a patient with rheumatoid arthritis. The absence of basic treatment and persistent activity of disease leads to fast progression of nephrotic stage of secondary amyloidosis in a young woman.

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2017_04_821-823.pdf553.81 KB